
Reactive oxygen species mediate hepatotoxicity induced by the Hsp90 inhibitor geldanamycin and its analogs
Keywords: 17-AAG, 17-(allylamino)-17-demethoxygeldanamycin; CDCFH2, 5-(and-6)-carboxy-2’,7’-dichlorodihydrofluorescein diacetate; DEMPO, 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline N-oxide; 17-DMAG, 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin; DMPO, 5,5-D