
Research ReportDose-dependent inhibition of GCPII to prevent and treat cognitive impairment in the EAE model of multiple sclerosis
Keywords: 2-PMPA; 2-(phosphonomethyl)pentanedioic acid; DMTs; disease-modifying therapies; EAE; experimental autoimmune encephalomyelitis; GCPII; glutamate carboxypeptidase II; NAA; N-acetylaspartate; NAAG; N-acetylaspartylglutamate; MS; multiple sclerosis; TGF; tr