New 4-[(5-arylidene-2-arylimino-4-oxo-3-thiazolidinyl)methyl]benzoic acids active as protein tyrosine phosphatase inhibitors endowed with insulinomimetic effect on mouse C2C12 skeletal muscle cells
Keywords: Enzyme inhibitor; Diabetes mellitus; Obesity; Protein tyrosine phosphatase; Insulinomimetic agent; Molecular dockingDM2, type 2 diabetes mellitus; 2-DOG, 2-deoxyglucose; IR, insulin receptor; IRS, insulin receptor substrate; JAK, Janus kinase; LMW-PTP, lo