دانلود مقالات ISI درباره 3Clpro + ترجمه فارسی

Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein

Keywords: Ubiquitin-like domain; Papain-like protease; Macrodomain; Nucleic-acid binding domain; Innate immunity; Structural biology; 3CLpro; 3C-like protease; 3Ecto; Nsp3 ectodomain; ADPr; ADP-ribose; ADRP; ADP-ribose-1″-phosphate phosphatase; ARTD; ADP-ribosylt

دانلود رایگان متن کامل مقاله ISI 87 صفحه سال انتشار : 2018 سفارش ترجمه

Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors

Keywords: MERS-CoV; SARS-Cov; 3CLpro; Coronavirus; Pyrazolone

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

X-ray structure and inhibition of the feline infectious peritonitis virus 3C-like protease: Structural implications for drug design

Keywords: Coronavirus; 3CLpro; Feline infectious peritonitis; Structure-based drug design; Peptidomimetics;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings

Keywords: SARS-CoV; Severe Acute Respiratory Syndrome coronavirus; 3CLpro; 3 Chymotrypsin-like cysteine protease; MD; molecular dynamics; VS; virtual screening; CSM; computational solvent mapping; ROC; receiver operating characteristic; RMSD; root mean square devia

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding

Keywords: 3CLpro; Severe acute respiratory syndrome; SARS; MERS; Coronavirus

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases

Keywords: IC50; the inhibitor concentration leading to 50% activity loss; Ki; inhibition constant; Kiapp; apparent Ki; k; rate constant; Vmax; maximum velocity; Km; Michaelis-Menten constant; kobs; apparent first-order rate constant for the transition from vi to vs

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

SARS-CoV 3CLpro inhibitory effects of quinone-methide triterpenes from Tripterygium regelii

Keywords: IC50, the inhibitor concentration leading to 50% activity loss; Ki, inhibition constant; Km, Michaelis–Menten constant; Vmax, maximum velocity; NMR, nuclear magnetic resonanceSARS-CoV; 3CLpro; Tripterygium regelii; Quinone-methide; Celastrol; Iguesterin

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Studies on the interactions of Ti-containing polyoxometalates (POMs) with SARS-CoV 3CLpro by molecular modeling

Keywords: SARS; 3CLpro; Molecular dynamics; Docking; Polyoxometalates (POMs)

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Binding interaction of SARS coronavirus 3CLpro protease with vacuolar-H+ ATPase G1 subunit

Keywords: SARS-coronavirus; 3CLpro; Vacuolar-H+ ATPase G1; Phage display; Human lung cDNA libraries

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه