Phosphoramidites and solid supports based on N-substituted 2,4-dihydroxybutyramides: universal reagents for synthesis of modified oligonucleotides
Keywords: Modified oligonucleotides; Phosphoramidites; 2,4-Dihydroxybutyramides; Imidazole; Pyrene; DIC; 1,3-diisopropylcarbodiimide; DMAP; 4-dimethylaminopyridine; Dmt; 4,4â²-dimethoxytrityl; Fmoc; 9-fluorenylmethoxycarbonyl; FmocOSu; 9-fluorenylmethyl N-succinim