Keywords: 4-Methylpyrazole; Ethylene glycol; Kidney; Oxidative stress;
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Keywords: 4-MP; 4-methylpyrazole; ADH; alcohol dehydrogenase; ALD; alcoholic liver disease; BHMT; betaine-homocysteine methyltransferase; CYP 2E1; cytochrome P 450 2E1; DMG; dimethylglycine; SAH; S-adenosylhomocysteine; TEER; transepithelial electric resistance; TJ
1,2-Dichloropropane generates phosphorylated histone H2AX via cytochrome P450 2E1-mediated metabolism
Keywords: 1,2-DCP; 1,2-dichloropropane; 4MP; 4-methylpyrazole; ABT; 1-aminobenzotriazole; BSA; bovine serum albumin; BSFGE; biased sinusoidal field gel; CYP2E1; electrophoresis; DAPI; 4â²,6-diamidino-2-phenylindole; DCFH-DA; 6-carboxy-2,7â²-diclorodihydrofluoresc
Is catalase involved in the effects of systemic and pVTA administration of 4-methylpyrazole on ethanol self-administration?
Keywords: Ethanol; Acetaldehyde; Oral operant self-administration; 4-Methylpyrazole; Catalase-H2O2 activity; Compound I; pVTA (posterior Ventral Tegmental Area); Wistar rats;
Challenges in assignment of allosteric effects in cytochrome P450-catalyzed substrate oxidations to structural dynamics in the hemoprotein architecture
Keywords: Cytochrome P450; Allosteric effects; Cooperativity; Key determinants; Molecular modeling; 1PB; 1-pyrenebutanol; 4MP; 4-methylpyrazole; 7BQ; 7-benzyloxyquinoline; 7EC; 7-ethoxycoumarin; 7EFC; 7-ethoxy-4-trifluoromethylcoumarin; 9AP; 9-aminophenanthrene; 9E
Cellular steatosis in ethanol oxidizing-HepG2 cells is partially controlled by the transcription factor, early growth response-1
Keywords: ADH; alcohol dehydrogenase; CYP2E1; cytochrome P450 2E1; Egr-1; early growth response-1 protein; 4-MP; 4-methylpyrazole; DMEM; Dulbecco's modified Eagle's medium; CMZ; chlormethiazole; Suc-LLVY-AMC; succinyl-leucyl-leucyl-7-amido-4-methyl-coumarin; trolox
Effect of 4-methylpyrazole on antioxidant enzyme status and lipid peroxidation in the liver of rats after exposure to ethylene glycol and ethyl alcohol
Keywords: 4-methylpyrazole; rat; liver; oxidative stress; ethylene glycol; ethyl alcohol
Piecing together the puzzle of acetaldehyde as a neuroactive agent
Keywords: 4MP; 4-methylpyrazole; AA; Alko alcohol; Acb; nucleus accumbens; AcbSh; nucleus accumbens shell; AcbC; nucleus accumbens core; aCSF; artificial cerebrospinal fluid; ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; ANA; alko non-alcohol; ANT; alco
Stabilization of superoxide dismutase by acetyl-l-carnitine in human brain endothelium during alcohol exposure: Novel protective approach
Keywords: BBB; blood-brain barrier; EtOH; ethanol; 4MP; 4-methylpyrazole; Ach; acetaldehyde; ALC; acetyl-l-carnitine; Rosi; rosiglitazone; AP; allopurinol; APC; apocyanin; DDC; diethyldithiocarbamate; Antioxidant; Brain endothelium; Reactive oxygen species; Super
Research ArticleTGF-β enhances alcohol dependent hepatocyte damage via down-regulation of alcohol dehydrogenase I
Keywords: ALD; alcoholic liver disease; CLD; chronic liver disease; TGF-β1; transforming growth factor-β1; 4-MP; 4-methylpyrazole; HSC; hepatic stellate cell; ECM; extracellular matrix; ADH; alcohol dehydrogenase; MEOS; microsomal ethanol oxidizing system; FAEE;
Involvement of alcohol and aldehyde dehydrogenase activities on hepatic retinoid metabolism and its possible participation in the progression of rat liver regeneration
Keywords: Liver proliferation; Retinol; Cellular retinal-binding protein (CRBP); 4-Methylpyrazole; Retinol/retinal ratio
Oxidative stress pathways in the potentiation of noise-induced hearing loss by acrylonitrile
Keywords: NIHL; noise-induced hearing loss; STS; sodium thiosulfate; 4MP; 4-methylpyrazole; l-NAC; l-N-acetylcysteine; ACN; acrylonitrile; OHCs; outer hair cells; GSH; glutathione; ROS; reactive oxygen species; CYP2E1; cytochrome P450 2E1; SOD; superoxide dismutase
The total antioxidant status in the brain after ethanol or 4-methylpyrazole administration to rats intoxicated with methanol
Keywords: Methanol; Ethanol; 4-methylpyrazole; Antioxidant status; Rat brain; N2O/O2;
Intérêt du traitement par 4-méthylpyrazole lors d'un syndrome antabuse avec critères de gravité
Keywords: Disulfiram; Effet antabuse; 4-méthylpyrazole; Alcool éthylique; Antabuse effect (disulfiram-ethanol reaction); Disulfiram; Ethyl alcohol; 4-methylpyrazole;
The role of acetaldehyde in the neurobehavioral effects of ethanol: A comprehensive review of animal studies
Keywords: 4-MP; 4-methylpyrazole; ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; AT; 3-amino-1,2,4-triazole; BBB; blood-brain barrier; CTA; conditioned taste aversion; CYP2E1; cytochrome P4502E1; H2O2; hydrogen peroxide; LTP; long term potentiation; TH