دانلود مقالات ISI درباره آگونیست گیرنده 5-HT4 + ترجمه فارسی

The in vitro pharmacology and non-clinical cardiovascular safety studies of a novel 5-HT4 receptor agonist, DSP-6952

Keywords: آگونیست گیرنده 5-HT4; 5-HT4 receptor agonist; Gastrointestinal prokinetic agent; Cardiovascular safety; QT prolongation; Cardiac ischemia;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

DSP-6952, a novel 5-HT4 receptor partial agonist, inhibits visceral hypersensitivity and ameliorates gastrointestinal dysfunction in experimental animals

Keywords: آگونیست گیرنده 5-HT4; 5-HT4 receptor agonist; Gastrointestinal motility; Visceral hypersensitivity; Gastroprokinetic; Irritable bowel syndrome; Constipation;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Combination of exogenous cell transplantation and 5-HT4 receptor agonism induce endogenous enteric neural crest-derived cells in a rat hypoganglionosis model

Keywords: آگونیست گیرنده 5-HT4; Enteric neural crest-derived cell; 5-HT4 receptor agonist; Cell transplantation; Enteric nervous system;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Chronic treatments with a 5-HT4 receptor agonist decrease amyloid pathology in the entorhinal cortex and learning and memory deficits in the 5xFAD mouse model of Alzheimer's disease

Keywords: آگونیست گیرنده 5-HT4; 5-HT4 receptor agonist; Alzheimer's disease; Memory impairments; Olfactory tubing maze; Transgenic mouse model; Pharmacotherapy; 5-HT4R; 5-Hydroxytryptamine type 4 receptor; Aβ; Amyloid beta peptide; AD; Alzheimer's Disease; ApoE; Apolipoprotein E; APP;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperChronic 5-HT4 receptor agonist treatment restores learning and memory deficits in a neuroendocrine mouse model of anxiety/depression

Keywords: آگونیست گیرنده 5-HT4; Cognitive deficits; Animal models of anxiety-depression; Fluoxetine; 5-HT4 receptor agonist;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Delivery of enteric neural progenitors with 5-HT4 agonist-loaded nanoparticles and thermosensitive hydrogel enhances cell proliferation and differentiation following transplantation in vivo

Keywords: آگونیست گیرنده 5-HT4; Enteric neuropathies; Cell therapy; Serotonin; 5-HT4 receptor agonist; Liposomal nanoparticles; Thermosensitive hydrogel;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Mosapride, a selective serotonin 5-HT4 receptor agonist, and alogliptin, a selective dipeptidyl peptidase-4 inhibitor, exert synergic effects on plasma active GLP-1 levels and glucose tolerance in mice

Keywords: آگونیست گیرنده 5-HT4; Mosapride; 5-HT4 receptor agonist; Alogliptin; DPP-4 inhibitor; GLP-1; Glucose tolerance

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Pharmacological profile of DA-6886, a novel 5-HT4 receptor agonist to accelerate colonic motor activity in mice

Keywords: آگونیست گیرنده 5-HT4; Irritable bowel syndrome; Constipation; 5-HT4 receptor agonist; Colonic transit;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Acute and subchronic toxicities of QX100626, a 5-HT4 receptor agonist, in rodents and Beagle dogs

Keywords: آگونیست گیرنده 5-HT4; 5-HT4 receptor agonist; QX100626; Safety assessment; GERT; Dyspepsia;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Discovery, oral pharmacokinetics and in vivo efficacy of a highly selective 5-HT4 receptor agonist: Clinical compound TD-2749

Keywords: آگونیست گیرنده 5-HT4; 5-HT4 receptor agonist; Multivalent approach; TD-2749; GI motility; Alzheimer’s

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Discovery, oral pharmacokinetics and in vivo efficacy of velusetrag, a highly selective 5-HT4 receptor agonist that has achieved proof-of-concept in patients with chronic idiopathic constipation

Keywords: آگونیست گیرنده 5-HT4; 5-HT4 receptor agonist; Multivalent approach; Velusetrag; TD-5108; GI motility; Alzheimer's;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Gastrokinetic activity of Morinda citrifolia aqueous fruit extract and its possible mechanism of action in human and rat models

Keywords: آگونیست گیرنده 5-HT4; Morinda citrifolia (L.); Aqueous noni fruit extract; Bioavailability; Gastrokinetic; Gastric emptying; 5-HT4 receptor agonist;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

5-HT4 receptor agonist mediated enhancement of cognitive function in vivo and amyloid precursor protein processing in vitro: A pharmacodynamic and pharmacokinetic assessment

Keywords: آگونیست گیرنده 5-HT4; 5-HT4 receptor agonist; sAPPα; Cholinesterase; Morris water maze; Receptor occupancy; VelusetragAD, Alzheimer's disease; ACh, acetylcholine; AChEi, acetylcholine esterase inhibitor; APP, amyloid precursor protein; sAPPα, soluble amyloid precursor protein

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Excitability of small-diameter trigeminal ganglion neurons by 5-HT is mediated by enhancement of the tetrodotoxin-resistant sodium current due to the activation of 5-HT4 receptors and/or by the inhibition of the transient potassium current

Keywords: آگونیست گیرنده 5-HT4; 5-HT3 receptor agonist; 5-HT4 receptor agonist; voltage-clamp; current-clamp; IA; action potential; DRG; dorsal root ganglion; G-V; conductance-voltage; IA; transient K+ current; IK; sustained K+ current; INaR; tetrodotoxin-resistant Na+ current; IT; to

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه