Edaravone, a free radical scavenger, protects neuronal cells' mitochondria from ischemia by inactivating another new critical factor of the 5-lipoxygenase pathway affecting the arachidonic acid metabolism
Keywords: 5-LOX; 5-lipoxygenase; MCAO; middle cerebral artery occlusion; OGD; oxygen glucose deprivation; OGD-R; OGD-reperfusion; CysLTs; cysteinyl leukotrienes; MTT; 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide; ROS; reactive oxygen species; E