A soluble phosphodiesterase in Leishmania donovani negatively regulates cAMP signaling by inhibiting protein kinase A through a two way process involving catalytic as well as non-catalytic sites
Keywords: L. donovani; Phosphodiesterase; Psudosubstrate residues; Phosphorylation; Protein kinase A; PDE; phosphodiesterase; DAPI; 4â²,6-diamidino-2â²-phenylindole dihydrochloride; LdPDEA; L. donovani cAMP phosphodiesterase A; LdPDED; L. donovani cAMP phosphodie