Keywords: ABC، کیت اتصال ATP; ABC, ATP Binding Cassette; ALK, activin receptor-like kinase; BBB, blood–brain barrier; BCRP, Breast Cancer Resistance Protein; CNS, central nervous system; GSH, glutathione; GSSG, glutathione disulfide; JAM, junctional adhesion molecule; MAGUK, membrane-
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Elevated nuclear sphingoid base-1-phosphates and decreased histone deacetylase activity after fumonisin B1 treatment in mouse embryonic fibroblasts
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; CerS, ceramide synthase; ELEM, equine leukoencephalomalacia; FB1, fumonisin B1; Gapdh, glyceraldehyde 3-phosphate dehydrogenase; GPCR, G protein-coupled receptor; HDAC, histone deacetylase; Lpp, lipid phosphate phosphatase; MEF,
An alternative reaction for heme degradation catalyzed by the Escherichia coli O157:H7 ChuS protein: Release of hematinic acid, tripyrrole and Fe(III)
Keywords: ABC، کیت اتصال ATP; ChuS, ChuS protein containing a N-terminal 6-histidine tag; apo-ChuS, heme-free ChuS; holo-ChuS, heme-bound ChuS; HO, heme oxygenase; HO-1, heme oxygenase-1; HO, heme oxygenase; ABC, ATP binding cassette; HRP, horseradish peroxidase; ms, millisecond; ADHP
Liposomal delivery systems for anti-cancer analogues of vitamin E
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; DCs, dendritic cells; DMSO, dimethylsulfoxide; DLPC, dilauroyl phosphatidylcholine; DOPE, dioleoyl phosphatidylethanolamine; EPC, egg phosphatidylcholine; EPR, enhanced permeability and retention; ETP, etoposide; FBS, fetal bovi
Mechanisms of resistance to EGFR tyrosine kinase inhibitors
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; ABCB1, ATP binding cassette, sub-family B, member 1; ABCC1, ATP binding cassette, sub-family C, member 1; ABCC10, ATP binding cassette, sub-family C, member 10; ABCG2, ATP binding cassette, sub-family G, member 2; AKT, protein k
Comparative genome analysis of five Pasteurella multocida strains to decipher the diversification in pathogenicity and host specialization
Keywords: ABC، کیت اتصال ATP; ABC, ATP Binding Cassette; BLAST, Basic Local Alignment Search Tool; LPS, lipopolysaccharide; Mb, mega base; MEGA, Molecular Evolutionary Genetics Analysis; NCBI, National Center for Biotechnology Information; OMP, outer membrane proteinMolecular pathogen
LXR antagonists induce ABCD2 expression
Keywords: ABC، کیت اتصال ATP; ACOX, Acyl-CoA oxidase; ABC, ATP binding cassette; DHA, docosahexaenoic acid (C22:6 n − 3); H2DCFDA, 2′,7′-dichlorodihydrofluorescein diacetate; HC, hydroxycholesterol; HFD, high fat diet; LXR, Liver X receptor; LXRE, LXR response element; MTE, multiple t
Combinatorial delivery of Crizotinib–Palbociclib–Sildenafil using TPGS-PLA micelles for improved cancer treatment
Keywords: ABC، کیت اتصال ATP; A549, human lung adenocarcinoma epithelial cell line; ABC, ATP binding cassette; ALK, anaplastic lymphoma kinase; ANOVA, analysis of variance; CI, combination index; CLSM, confocal laser scanning microscopy; C-M, crizotinib micelles; CMC, critical micella
Naphthalenyl derivatives for hitting P-gp/MRP1/BCRP transporters
Keywords: ABC، کیت اتصال ATP; MDR, MultiDrug Resistance; ABC, ATP Binding Cassette; P-gp, P-glycoprotein; BCRP, Breast Cancer Resistance Protein; MRP1, MultiDrug Resistance-associated Protein1; Papp, apparent permeability; Calcein-AM, Acetoxymethyl esters of calcein; MDCK, Madin-Darby
Neonatal exposure to zearalenone induces long term modulation of ABC transporter expression in testis
Keywords: ABC، کیت اتصال ATP; ABC, ATP Binding Cassette; ABCB1/Abcb1a-b, ATP Binding Cassette, subfamily B, member 1A-B; ABCC1-5/Abcc1-5, ATP Binding Cassette, subfamily C, member 1–5; ABCG2/Abcg2, ATP Binding Cassette, subfamily G, member 2; Actb, Actin, beta; BTB, blood testis barri
Alanine scanning of all cysteines and construction of a functional cysteine-less Cdr1p, a multidrug ABC transporter of Candida albicans
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; MFS, major facilitator superfamily; MDR, multidrug resistance; MIC, minimum inhibitory concentration; FLC, fluconazole; CYH, cycloheximide; ITR, itraconazole; KTC, ketoconazole; MIC, miconazole; ANI, anisomycin; DIC, differentia
Ycf1p attenuates basal level oxidative stress response in Saccharomyces cerevisiae
Keywords: ABC، کیت اتصال ATP; Ycf1p; Salt stress; Super oxide dismutase; Catalase; Glutathione; Glutathione peroxidaseYCF1, yeast cadmium factor 1; SOD, superoxide dismutase; GPx, glutathione peroxidase; CAT, catalase; ROS, reactive oxygen species; ABC, ATP binding cassette
Zearalenone exposure modulates the expression of ABC transporters and nuclear receptors in pregnant rats and fetal liver
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; Abcb1a–b, ATP binding cassette, subfamily B, member 1A–B; Abcc1–3, ATP binding cassette, subfamily C, member 1–3; Abcg2, ATP binding cassette, subfamily G, member 2; Actb, actin, beta; Cq, cycle of quantification; E2, 17 β estra
Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; AF, activation function; AhR, aryl hydrocarbon receptor; AHRE, AhR element; AIP, aryl hydrocarbon receptor-interacting protein; AKRs, aldo–keto reductases; ARE, antioxidant response element; ARNT, aryl hydrocarbon receptor nucle
Structural Basis of Substrate Binding Specificity Revealed by the Crystal Structures of Polyamine Receptors SpuD and SpuE from Pseudomonas aeruginosa
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; Mes, 4-morpholineethanesulfonic acid; ITC, isothermal titration calorimetry; MBP, maltodextrin binding protein; NTA, nitrilotriacetic acid; GST, glutathione S-transferase; RT-PCR, reverse transcription polymerase chain reaction;
Catalytic activity of MsbA reconstituted in nanodisc particles is modulated by remote interactions with the bilayer
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; NBD, nucleotide-binding domain; β-DDM, n-dodecyl-β-d-maltoside; DMPC, 1,2-dimyristoyl-sn-glycero-3-phosphocholine; DMPG, 1,2-dimyristoyl-sn-glycero-3-phospho-(1′-rac-glycerol); DLPC, 1,2-dilauroyl-sn-glycero-3-phosphocholine; DM
Long evolutionary conservation and considerable tissue specificity of several atypical solute carrier transporters
Keywords: ABC، کیت اتصال ATP; SLC, Solute Carriers; MFS, Major facilitator superfamily; ABC, ATP binding cassette; ATP, Adenosine triphosphate; AA, Aminoacid; TC, Transporter classification; RT-PCR, Real time polymerase chain reaction; CNS, Central nervous system; APC, Aminoacid, poly
A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells
Keywords: ABC، کیت اتصال ATP; LDL, low density lipoprotein; LDLR, low density lipoprotein receptor; Pgp, P-glycoprotein; MDR, multidrug resistance; ABC, ATP binding cassette; NO, nitric oxide; HMGCR, 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Lipodox, liposomal doxorubicin; apo-
Cholesterol metabolism in neurons and astrocytes
Keywords: ABC، کیت اتصال ATP; Neuroglia; Membrane lipids; Steroids; Apolipoproteins; Lipoproteins; Neurodegenerative diseases24OHC, 24S-hydroxycholesterol; ABC, ATP binding cassette; CSF, cerebrospinal fluid; CNS, central nervous system; DRG, dorsal root ganglion; ER, endoplasmic reti
Breast cancer chemoresistance: Emerging importance of cancer stem cells
Keywords: ABC، کیت اتصال ATP; Cancer stem cells; Breast cancer; ChemoresistanceCSCs, cancer stem cells; ABC, ATP binding cassette; SP, side population; ALDH1, aldehyde dehydrogenase-1; VEGF, vascular endothelial growth factor
Influence of SCARB1 polymorphisms on serum lipids of hypercholesterolemic individuals treated with atorvastatin
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; apoAI, apolipoprotein AI; apoB, apolipoprotein B; CAD, coronary artery disease; HC, hypercholesterolemic; HCb, hypercholesterolemic individuals at baseline; HCp10, hypercholesterolemic individuals after 10 mg/day/4 week atorvast
Role of basolateral efflux transporter MRP4 in the intestinal absorption of the antiviral drug adefovir dipivoxil
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; DMEM, Dulbecco's Modified Eagle Medium; EMEM, Eagle's minimum essential medium; FBS, Fetal bovine serum; HBSS, Hank's balanced salt solution; HEPES, N-hydroxyethylpiperazine-N′-2-ethanesulfonate; h, human; MDCKII, Madin–Darby Ca
Low-density lipoprotein and oxysterols suppress the transcription of CTP:Phosphoethanolamine cytidylyltransferase in vitro
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; CT, CTP:phosphocholine cytidylyltransferase; ET, CTP:phosphoethanolamine cytidylyltransferase; ER, endoplasmic reticulum; FBS, fetal bovine serum; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HMG-CoA, 3-hydroxy-3-methylgluta
The liver X receptor: Control of cellular lipid homeostasis and beyond: Implications for drug design
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; ACAT, acyl-CoA:cholesterol O-acyltransferase; ACTH, adrenocorticotropic hormone; Angptl3, angiopoietin-like protein 3; Apo, apolipoprotein; CA, co-activator; CE, cholesteryl-ester; CETP, cholesteryl-ester transfer protein; ChREB
Divergent signature motifs of nucleotide binding domains of ABC multidrug transporter, CaCdr1p of pathogenic Candida albicans, are functionally asymmetric and noninterchangeable
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; PDR, pleiotropic drug resistance; NBD, nucleotide binding domain; TMD, transmembrane domain; TMS, transmembrane segment; PM, plasma membrane; FLC, fluconazole; CYH, cycloheximide; ANI, anisomycin; R6G, rhodamine 6G; [125I] IAAP,
ATP Binding, ATP Hydrolysis, and Protein Dimerization Are Required for RecF to Catalyze an Early Step in the Processing and Recovery of Replication Forks Disrupted by DNA Damage
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; SSB, single-strand DNA binding proteinRecF; DNA binding; DNA replication; structural maintenance of chromosome (SMC) proteins; ATP binding cassette (ABC) ATPases
Conformational Changes and Ligand Recognition of Escherichia colid-Xylose Binding Protein Revealed
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; XBP, d-xylose binding protein; TtRBP, Thermoanaerobacter tengcongensis ribose binding protein; PDB, Protein Data Bank; RBP, ribose binding protein; ALBP, allose binding protein; ESRF, European Synchrotron Radiation Facilityprote
The role of multixenobiotic transporters in predatory marine molluscs as counter-defense mechanisms against dietary allelochemicals
Keywords: ABC، کیت اتصال ATP; ABC, ATP Binding Cassette; C-AM, Calcein-AM; MRP, Multidrug resistance-associated protein; P-gp, P-glycoproteinABC transporter; Allelochemical; Calcein-AM; Gorgonian; MK571; MRP; P-gp; Verapamil
Defective lipid transport and biosynthesis in recessive and dominant Stargardt macular degeneration
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; MD, macular degeneration; RP, retinitis pigmentosa; AMD, age-related macular degeneration; RPE, retinal pigment epithelial; ELOVL, elongation of very long-chain fatty acids; ERGs, electroretinograms; TMD, transmembrane domain; N
Increased NPC1L1 and ACAT2 expression in the jejunal mucosa from Chinese gallstone patients
Keywords: ABC، کیت اتصال ATP; ACAT, acyl-coenzyme A: cholesteryl acyltransferase; ABC, ATP binding cassette; apoA1, apolipoprotein A1; CYP7A1, cholesterol 7α-hydroxylase; DGAT, diacyl glycerol acyl transferase; HMGCR, 3-hydroxy-3-methylglutaryl coenzyme A reductase; LXR, liver X recep
Treatment of resistant human colon cancer xenografts by a fluoxetine–doxorubicin combination enhances therapeutic responses comparable to an aggressive bevacizumab regimen
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; BCRP, breast cancer resistance protein; BSA, bovine serum albumin; FBS, fetal bovine serum; HBS, hepes buffered saline; MDR, multiple drug resistance; MRP, multidrug resistance-associated protein; PBS, phosphate buffered saline;
Ins and outs of the ABCG2 multidrug transporter: An update on in vitro functional assays
Keywords: ABC، کیت اتصال ATP; ABC, ATP Binding Cassette; ABCP placenta-specific, ABC transporter; ADME-Tox, absorption, distribution, metabolism, excretion, and toxicology; BCRP, breast cancer resistance protein; MXR, mitoxantrone resistance protein; MDR, Multidrug Resistance; NBD, Nu
Emerging new paradigms for ABCG transporters
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; DKO, double knock-out; HDL, high-density lipoprotein; LDL, low-density lipoprotein; LXR, liver X receptor; TMD, transmembrane domainABC transporter; ABCG; Sterol transporter; Multidrug resistance; Sitosterolemia; Atherosclerosis
Lipoprotein MtsA of MtsABC in Streptococcus pyogenes primarily binds ferrous ion with bicarbonate as a synergistic anion
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; E. coli, Escherichia coli; ICP-MS, inductively coupled plasma mass spectroscopy; IPTG, isopropyl β-d-thiogalactoside; MALDI, matrix-assisted laser-desorption ionization; NMR, nuclear magnetic resonance; PMF, peptide-mass-fingerp
Expression and function of TETRAN, a new type of membrane transporter
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; COX, cyclooxygenase; MATE, multidrug and toxin extrusion; MFS, major facilitator super-family; MRP, multidrug resistance-associated protein; NPT, sodium-dependent inorganic phosphate transporter; NSAID, non-steroidal anti-inflam
Quercetin increases the bioavailability of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rats
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; BCRP, breast cancer resistance protein; CYP, cytochrome P450; MDCK, Madin–Darby Canine Kidney; MRP, multidrug resistance protein; P-gp, P-glycoprotein (MDR1); PhIP, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; SD, Sprague–Da
Structural stability of GlcV, the nucleotide binding domain of the glucose ABC transporter of Sulfolobus solfataricus
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; DSC, differential scanning calorimetry; GdnCl, Guandiniumchloride; NBD, nucleotide binding domain; wt, wild-type; AMP-PNP, adenosine-(β,γ-imido)triphosphateABC transporters; Nucleotide binding; Differential scanning calorimetry;
Functional characterization of the Saccharomyces cerevisiae ABC-transporter Yor1p overexpressed in plasma membranes
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; TMD, Transmembrane domain; NBD, Nucleotide binding domain; P-gp, P-glycoprotein; CFTR, Cystic fibrosis transmembrane conductance regulator; MRP, Multidrug resistance associated protein; p-CMPS, p-chloromercuriphenylsulfonate; DC
P-glycoprotein-like protein, a possible genetic marker for ivermectin resistance selection in Onchocerca volvulus
Keywords: ABC، کیت اتصال ATP; IVM, ivermectin; PLP, P-glycoprotein-like protein; OvPLP, Onchocerca volvulus P-glycoprotein-like-protein gene; ABC, ATP binding cassette; Pgp, P-glycoprotein; OvPgp, Onchocerca volvulus P-glycoprotein gene; hsp60, heat shock protein 60; SNP, single nucle
A novel catalytic mechanism for ATP hydrolysis employed by the N-terminal nucleotide-binding domain of Cdr1p, a multidrug ABC transporter of Candida albicans
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; MFS, Major Facilitator Superfamily; ATP, adenosine triphosphate; DTE, dithioerythritol; FRET, fluorescence resonance energy transfer; MIANS, 2′-(4′-maleimidylanilino)naphthalene-6-sulfonic acid; NBD, nucleotide-binding domain; T
The hydroxyl group of S685 in Walker A motif and the carboxyl group of D792 in Walker B motif of NBD1 play a crucial role for multidrug resistance protein folding and function
Keywords: ABC، کیت اتصال ATP; BHK, baby hamster kidney; Sf21, Spodoptera frugiperda 21; ABC, ATP binding cassette; MRP1, multidrug resistance protein 1; P-gp, P-glycoprotein; CFTR, cystic fibrosis trans-membrane conductance regulator; BSA, bovine serum albumin; NBD, nucleotide binding
Proteome of the Escherichia coli envelope and technological challenges in membrane proteome analysis
Keywords: ABC، کیت اتصال ATP; 2MEGA, dimethylation after lysine guanidination; ABC, ATP binding cassette; CNBr, cyanogen bromide; ESI, electrospray ionization; ICAT, isotope-coded affinity tag; IEF, isoelectric focusing; IMP, inner membrane protein; LC, liquid chromatography; MAAH, mi
Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP
Keywords: ABC، کیت اتصال ATP; Mdr1, multidrug resistance 1 gene; ABC, ATP binding cassette; TMD, transmembrane domain; NBD, nucleotide binding domain; AMP-PNP, adenosine-5′-(β,γ-imido)triphosphate; ADP, adenosine diphosphate; ATP, adenosine triphosphate; SDS–PAGE, sodium dodecyl sulfa
CFTR inhibition by glibenclamide requires a positive charge in cytoplasmic loop three
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; CFTR, cystic fibrosis transmembrane conductance regulator; MRP, multidrug resistance-associated protein; SUR, sulfonylurea receptor; CL, cytoplasmic loop; TMD, transmembrane domain; Fsk, forskolin; Glib, glibenclamide; HEK, huma
Sphingosine-1-phosphate in allergic responses, asthma and anaphylaxis
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; Ag, antigen; AHR, airway hyperresponsiveness; ASM, airway smooth muscle; BAL, bronchoalveolar lavage; BMMC, bone marrow-derived mast cells; COX, cyclooxygenase; ER, endoplasmic reticulum; ERK, extracellular signal regulated kina
Effect of acetaminophen administration to rats chronically exposed to depleted uranium
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; CYP, cytochrome P450; ALT, alanine amino-transferase; APAP, acetaminophen; AST, aspartate amino-transferase; DU, depleted uranium; GST, glutathione-S-transferase; HPRT, hypoxanthine–guanine phosphoribosyltransferase; MDR, multid
Modulation of GSH levels in ABCC1 expressing tumor cells triggers apoptosis through oxidative stress
Keywords: ABC، کیت اتصال ATP; MRP1 or ABCC1, multidrug resistance associated protein; ROS, reactive oxygen species; GSH, glutathione; ABC, ATP binding cassette; MDR, multidrug resistance; BSO, l-buthionine (S,R)-sulfoximine; API, apigenin; VRP, verapamil; MTT, 3-(4,5-dimethylthiazol-2
Hydrogen-bond formation of the residue in H-loop of the nucleotide binding domain 2 with the ATP in this site and/or other residues of multidrug resistance protein MRP1 plays a crucial role during ATP-dependent solute transport
Keywords: ABC، کیت اتصال ATP; BHK, baby hamster kidney; Sf21, Spodoptera frugiperda 21; ABC, ATP binding cassette; MRP1, multidrug resistance protein; P-gp, P-glycoprotein; NBD, nucleotide binding domain; LTC4, leukotriene C4; 8-N3ATP, 8-azidoadenosine 5′-triphosphate; EGTA, ethylene
Co-expression of human ABCG5 and ABCG8 in insect cells generates an androstan stimulated membrane ATPase activity
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; DHEA, dehydroepiandrosterone; GST, glutathione-S-transferase; SLA, 3-doxyl-17β-hydroxy-5α-androstane; RAMEB, random methylated β-cyclodextrinSitosterolemia; Steroid hormones; ATP binding cassette transporters
The structures of MsbA: Insight into ABC transporter-mediated multidrug efflux
Keywords: ABC، کیت اتصال ATP; ABC, ATP binding cassette; ICD, intercellular domain; LPS, lipopolysaccharide; MDR, multidrug resistance; NBD, nucleotide binding domain; P-gp, P-glycoprotein; TMD, transmembrane binding domain; EM, electron microscopyMultidrug resistance; ABC transporter