Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia
Keywords: عبیل کیناز; PDGFR kinase; Type II inhibitor; Kinase inhibitor; CEL; PDGFR; platelet-derived growth factor receptor; RTK; Receptor Tyrosine Kinases; ABL kinase; Abelson kinase; KIT kinase; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; RTK; receptor ty