
The crystal structure of an isopenicillin N synthase complex with an ethereal substrate analogue reveals water in the oxygen binding site
Keywords: AC-; δ-l-α-aminoadipoyl-l-cysteinyl-; ACaI; AC-d-allo-isoleucine; ACI; AC-d-isoleucine; ACmaT; AC-O-methyl-d-allo-threonine; ACmT; AC-O-methyl-d-threonine; ACtaI; AC-d-thio-allo-isoleucine; ACtI; AC-d-thioisoleucine; ACV; AC-d-valine; IPN; isopenicillin