
Design and synthesis of peptide-MCA substrates for a novel assay of histone methyltransferases and their inhibitors
Keywords: AcOH, acetic acid; Ac2O, acetic anhydride; AcOEt, ethyl acetate; AMC, 7-amino-4-methylcoumarin; DCM, dichloromethane; DCC, dicyclohexylcarbodiimide; DIEA, N,N-diisopropylethylamine; DMF, N,N-dimethylformamide; Fmoc, fluorenylmethyloxycarbonyl; HOBt·H2O, 1