دانلود مقالات ISI درباره مقاومت به دست آورد + ترجمه فارسی

BE-POSITIVE: Beyond progression after tyrosine kinase inhibitor in EGFR- positive non small cell lung cancer patients

Keywords: مقاومت به دست آورد; ESMO; European Society for Medical Oncology; ASCO; American Society of Clinical Oncology; ECOG; Eastern Cooperative Oncology Group; Non small cell lung cancer; EGFR mutation; EGFR tyrosine kinase inhibitors; First line; Second line; Acquired resistance;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

High MET amplification level as a resistance mechanism to osimertinib (AZD9291) in a patient that symptomatically responded to crizotinib treatment post-osimertinib progression

Keywords: مقاومت به دست آورد; Osimertinib; METamplification; Third-generation EGFR TKI; Acquired resistance; Non-small-cell lung cancer;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The ERK cascade inhibitors: Towards overcoming resistance

Keywords: مقاومت به دست آورد; MAPK; Cancer; Intrinsic resistance; Acquired resistance; BRAF-mutated melanoma; ERK translocation;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Strategies to Improve Outcomes of Patients with EGFR-Mutant Non–Small Cell Lung Cancer: Review of the Literature

Keywords: مقاومت به دست آورد; Non–small cell lung cancer; Epidermal growth factor receptor tyrosine kinase inhibitor; Acquired resistance; Combination strategy

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Anaplastic Lymphoma Kinase (ALK) Kinase Domain Mutation Following ALK Inhibitor(s) Failure in Advanced ALK Positive Non-Small-Cell Lung Cancer: Analysis and Literature Review

Keywords: مقاومت به دست آورد; Acquired resistance; Alectinib; ALK inhibitor resistance; Ceritinib; Crizotinib;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Mechanisms of allergy and clinical immunologyIgE antibodies, FcεRIα, and IgE-mediated local anaphylaxis can limit snake venom toxicity

Keywords: مقاومت به دست آورد; Acquired resistance; allergy; Daboia russelii; Russell viper; FcεRIα; honeybee; IgE; toxin hypothesis; venom; mast cells; type 2 immunity; BMCMC; Bone marrow-derived cultured mast cell; BV; Honeybee venom; bvPLA2; Honeybee venom phospholipase A2; DNP;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Transformation to large cell neuroendocrine carcinoma as acquired resistance mechanism of EGFR tyrosine kinase inhibitor

Keywords: مقاومت به دست آورد; Acquired resistance; Epidermal growth factor receptor; Large-cell neuroendocrine carcinoma; Transformation; Tyrosine kinase inhibitor;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Prospective Assessment of Pemetrexed or Pemetrexed Plus Platinum in Combination With Gefitinib or Erlotinib in Patients With Acquired Resistance to Gefitinib or Erlotinib: A Phase II Exploratory and Preliminary Study

Keywords: مقاومت به دست آورد; Acquired resistance; Non-small-cell lung cancer; Pemetrexed; Platinum; Progression-free survival;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Spatiotemporal T790M Heterogeneity in Individual Patients with EGFR-Mutant Non–Small-Cell Lung Cancer after Acquired Resistance to EGFR-TKI

Keywords: مقاومت به دست آورد; Epidermal growth factor receptor mutation; T790M; Epidermal growth factor receptor-tyrosine kinase inhibitor; Acquired resistance; Rebiopsy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanisms of Acquired Resistance to AZD9291 : A Mutation-Selective, Irreversible EGFR Inhibitor

Keywords: مقاومت به دست آورد; Acquired resistance; AZD9291; Epidermal growth factor receptor T790M mutation; Non–small-cell lung cancer

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Acquired resistance to the 16-membered macrolides tylosin and tilmicosin by Mycoplasma bovis

Keywords: مقاومت به دست آورد; Mycoplasma bovis; Acquired resistance; Tylosin; Tilmicosin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Update on antifungal resistance in Aspergillus and Candida

Keywords: مقاومت به دست آورد; Acquired resistance; Aspergillus; azoles; Candida; echinocandins; intrinsic resistance; susceptibility testing

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

MiR-21 overexpression is associated with acquired resistance of EGFR-TKI in non-small cell lung cancer

Keywords: مقاومت به دست آورد; Non-small cell lung cancer; miR-21; EGFR-TKI; Acquired resistance; PTEN; PDCD4; PI3K/Akt;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer: A new era begins

Keywords: مقاومت به دست آورد; Non-small cell lung cancer; Acquired resistance; Tyrosine kinase inhibitors; EGFR-mutant tumors;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Original StudyActivity of the EGFR-HER2 Dual Inhibitor Afatinib in EGFR-Mutant Lung Cancer Patients With Acquired Resistance to Reversible EGFR Tyrosine Kinase Inhibitors

Keywords: مقاومت به دست آورد; Acquired resistance; Afatinib; Erlotinib; Gefitinib; NSCLC;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Acquired resistance to EGFR-targeted therapies in colorectal cancer

Keywords: مقاومت به دست آورد; Anti-EGFR therapy; Cetuximab; Panitumumab; Colorectal cancer; Acquired resistance; RAS; MET

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Differential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanoma

Keywords: مقاومت به دست آورد; ERK inhibitors; BRAF inhibitors; MEK inhibitors; Melanoma; Acquired resistance;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

CRKL amplification is rare as a mechanism for acquired resistance to kinase inhibitors in lung cancers with epidermal growth factor receptor mutation

Keywords: مقاومت به دست آورد; Acquired resistance; Gefitinib; Erlotinib; Molecular target therapy; EGFR mutation; T790M mutation; MET gene amplification;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2014 سفارش ترجمه

Overcoming acquired resistance to kinase inhibition: The cases of EGFR, ALK and BRAF

Keywords: مقاومت به دست آورد; Kinase inhibition; Acquired resistance; Oncology;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Breakpoints for antifungal agents: An update from EUCAST focussing on echinocandins against Candida spp. and triazoles against Aspergillus spp.

Keywords: مقاومت به دست آورد; Echinocandins; Azoles; Acquired resistance; Susceptibility testing; Breakpoints; EUCAST; CLSI; MIC; Candida; Aspergillus;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Gene expression profiling for analysis acquired oxaliplatin resistant factors in human gastric carcinoma TSGH-S3 cells: The role of IL-6 signaling and Nrf2/AKR1C axis identification

Keywords: مقاومت به دست آورد; AKR1Cs; aldo-keto reductase family members (e.g. AKR1C1, AKR1C2, or AKR1C3); ARE; antioxidant response element; cisplatin; cis-diamminedichloroplatinum(II) (CDDP); ERCC-1; excision repair cross-complementing-1; ERK; extracellular signal-related kinase; FF

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Clinical perspective of afatinib in non-small cell lung cancer

Keywords: مقاومت به دست آورد; Non-small cell lung cancer; Afatinib; Epthelial growth factor receptor; Acquired resistance; Tyrosine kinase inhibitior

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Heterogeneity of Genetic Changes Associated with Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancer

Keywords: مقاومت به دست آورد; Anaplastic lymphoma kinase; Non–small-cell lung cancer; Crizotinib; Acquired resistance; ALK mutation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The anti-proliferative effect of heat shock protein 90 inhibitor, 17-DMAG, on non-small-cell lung cancers being resistant to EGFR tyrosine kinase inhibitor

Keywords: مقاومت به دست آورد; Hsp90; Hsp90 inhibitor; 17-DMAG; Gefitinib; EGFR mutation; EGFR-TKI; Acquired resistance

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

XL647—A Multitargeted Tyrosine Kinase Inhibitor: Results of a Phase II Study in Subjects with Non-small Cell Lung Cancer Who Have Progressed after Responding to Treatment with Either Gefitinib or Erlotinib

Keywords: مقاومت به دست آورد; EGFR-sensitizing mutation; EGFR-resistance mutation; Tyrosine kinase inhibitors; Acquired resistance; Molecular analysis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Conversion from the “oncogene addiction” to “drug addiction” by intensive inhibition of the EGFR and MET in lung cancer with activating EGFR mutation

Keywords: مقاومت به دست آورد; EGFR mutation; Acquired resistance; Tyrosine kinase inhibitors; Molecular target therapy; Irreversible EGFR inhibitor; PTEN;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

EGFR-Mutant Lung Adenocarcinomas Treated First-Line with the Novel EGFR Inhibitor, XL647, Can Subsequently Retain Moderate Sensitivity to Erlotinib

Keywords: مقاومت به دست آورد; Non-small cell lung cancer; EGFR mutations; XL647; EGFR tyrosine kinase inhibitors; Acquired resistance; Gefitinib; Erlotinib; Afatinib

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Phase II Study of the Multitargeted Tyrosine Kinase Inhibitor XL647 in Patients with Non–Small-Cell Lung Cancer

Keywords: مقاومت به دست آورد; EGFR-sensitizing mutation; EGFR-resistance mutation; Tyrosine kinase inhibitor; Acquired resistance; Molecular analysis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of Pharmacokinetic Processes and Varied Dosing Schedules on the Dynamics of Acquired Resistance to Erlotinib in EGFR-Mutant Lung Cancer

Keywords: مقاومت به دست آورد; EGFR-mutant lung cancer, Erlotinib; Evolutionary cancer modeling; Pharmacokinetic modeling; Acquired resistance; EGFR T790M mutation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Phase II Trial of Dasatinib for Patients with Acquired Resistance to Treatment with the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors Erlotinib or Gefitinib

Keywords: مقاومت به دست آورد; Acquired resistance; Lung adenocarcinoma; EGFR mutation; Targeted therapies; SRC kinase

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Expression of selected gene for acquired drug resistance to EGFR-TKI in lung adenocarcinoma

Keywords: مقاومت به دست آورد; EGFR; epidermal growth factor receptor; TKI; tyrosine kinase inhibitor; EMT; epithelial-mesenchymal transition; T790M; threonine-to-methionine mutation at codon 790 of EGFR; p-MET; phosphorylation of MET; p-Akt; phosphorylation of Akt; IHC; immunohistoc

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Epithelial to Mesenchymal Transition in an Epidermal Growth Factor Receptor-Mutant Lung Cancer Cell Line with Acquired Resistance to Erlotinib

Keywords: مقاومت به دست آورد; Acquired resistance; Erlotinib; Epithelial to mesenchymal transition; Epidermal growth factor receptor gene mutation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Acquired resistance to rechallenge injury in rats recovered from subclinical renal damage with uranyl acetate—Importance of proliferative activity of tubular cells

Keywords: مقاومت به دست آورد; Acquired resistance; Acute renal failure; Apoptosis; Divided cell; Proliferation; Uranyl acetate

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Quantifying the sensitivities of EGF receptor (EGFR) tyrosine kinase inhibitors in drug resistant non-small cell lung cancer (NSCLC) cells using hydrogel-based peptide array

Keywords: مقاومت به دست آورد; Peptide array; EGFR tyrosine kinase; Polyacrylamide; EGFR inhibitors; Acquired resistance

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Acquired resistance to cetuximab is mediated by increased PTEN instability and leads cross-resistance to gefitinib in HCC827 NSCLC cells

Keywords: مقاومت به دست آورد; Cetuximab; Gefitinib; Acquired resistance; PTEN; Akt

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Targeting epidermal growth factor receptor: Central signaling kinase in lung cancer

Keywords: مقاومت به دست آورد; Non-small cell lung cancer; Epidermal growth factor receptor tyrosine kinase inhibitors; Gefitinib; Erlotinib; Acquired resistance

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

EGFR T790M Mutation: A Double Role in Lung Cancer Cell Survival?

Keywords: مقاومت به دست آورد; Molecular target therapy; EGFR mutation; Acquired resistance; EGFR tyrosine kinase inhibitor

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Prospective phase II study of gefitinib in non-small cell lung cancer with epidermal growth factor receptor gene mutations

Keywords: مقاومت به دست آورد; EGFR; NSCLC; Adenocarcinoma; Prospective study; Acquired resistance; T790M

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

α-Toxin of Staphylococcus aureus overcomes acquired cisplatin-resistance in malignant mesothelioma cells

Keywords: مقاومت به دست آورد; Staphylococcal α-toxin; α-Hemolysin; Cisplatin; Acquired resistance; Apoptosis; α-Toxin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Acquired macrolide resistance in the human intestinal strain Lactobacillus rhamnosus E41 associated with a transition mutation in 23S rRNA genes

Keywords: مقاومت به دست آورد; Lactobacillus rhamnosus; Lactic acid bacteria; Erythromycin resistance; Acquired resistance; 23S rRNA genes

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Breast cancer resistance protein (BCRP) affected acquired resistance to gefitinib in a “never-smoked” female patient with advanced non-small cell lung cancer

Keywords: مقاومت به دست آورد; BCRP; Acquired resistance; EGFR; Gefitinib;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Persistence of host response against glochidia larvae in Micropterus salmoides

Keywords: مقاومت به دست آورد; Glochidia; Antibodies; Acquired resistance; Unionidae; Largemouth bass

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Interpretation of the results of antimicrobial susceptibility analysis of Escherichia coli isolates from bovine milk, meat and associated foodstuffs

Keywords: مقاومت به دست آورد; Clinical breakpoints; Microbiological breakpoints; Antimicrobial susceptibility; Escherichia coli; Acquired resistance;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Conservation of in vitro drug resistance patterns in epithelial ovarian carcinoma

Keywords: مقاومت به دست آورد; Chemoresistance assay; Acquired resistance; Tumor heterogeneity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه