Modulation of signaling through GPCR-cAMP-PKA pathways by PDE4 depends on stimulus intensity: Possible implications for the pathogenesis of acrodysostosis without hormone resistance
Keywords: cAMP; PDE4D; Acrodysostosis; BRET; Inhibition; Hormonal response; ACRDYS1; acrodysostosis with hormone resistance; ACRDYS2; acrodysostosis without hormone resistance; BRET; bioluminescence resonance energy transfer; 8-Br-cAMP; 8-Bromoadenosine 3,5-cyclic