
Cardiac voltage-gated ion channels in safety pharmacology: Review of the landscape leading to the CiPA initiative
Keywords: Action potential (AP); Action potential duration (APD); Cardiac voltage-gated ion channels; INa; Ito; IK1; hERG; IKs; In-vitro study; Cardiac action potential; Early afterdepolarization (EAD); Delayed afterdepolarization (DAD); Cardiac arrhythmias; QT pro