دانلود مقالات ISI درباره AD، بیماری آلزایمر + ترجمه فارسی

Chronic hypoxia in the human neuroblastoma SH-SY5Y causes reduced expression of the putative α-secretases, ADAM10 and TACE, without altering their mRNA levels

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, amyloid-β-peptide; ADAM10, a disintegrin and metalloproteinase 10; ADAM17, a disintegrin and metalloproteinase 17; APP, amyloid precursor protein; BACE1, β-amyloid converting enzyme; CH, chronic hypoxia; sAPPα, soluble α-secre

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Altered levels of PP2A regulatory B/PR55 isoforms indicate role in neuronal differentiation

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; BDNF, brain-derived neurotrophic factor; OA, okadaic acid; PP2A, protein phosphatase 2A; RA, all-trans retinoic acidHEK293 cells; Neuronal; PR55 regulatory subunits; Protein phosphatase 2A; qRT-PCR; SH-SY5Y cells; Western blotting

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Active immunization trial in Aβ42-injected P301L tau transgenic mice

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; NFT, neurofibrillary tangle; Aβ, amyloid β-peptide; i.c., intracerebralAlzheimer's disease; Brain; Vaccination; Amyloid β-peptide; Tau; Transgenic; Neurofibrillary tangles

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

GAPDH as a sensor of NO stress

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; iNOS, inducible nitric oxide synthase; MAO-B, monoamine oxidase B; NLS, nuclear localization signal; NMDA, N-methyl-d-aspartate; nNOS, neuronal nitric oxide synthase; NO, nitric oxi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Protection of amyloid β protein (25–35)-induced neurotoxicity by methanol extract of Smilacis chinae rhizome in cultured rat cortical neurons

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, amyloid β protein; [Ca2+]c, cytosolic calcium concentration; DMSO, dimethylsulfoxide; H2DCF-DA, 2′,7′-dichlorodihydrofluorescin diacetate; MK-801, (5R,10S)-(+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine; MTT,

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Effects of statins beyond lipid lowering: Potential for clinical benefits

Keywords: AD، بیماری آلزایمر; Aβ, beta-amyloid; AD, Alzheimer's disease; AMD, age-related macular degeneration; APP, amyloid precursor protein; BNP, B-type (brain) natriuretic peptide; CGN, chronic glomerulonephritis; CHD, coronary heart disease; CHF, congestive (chronic) heart failur

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Comparative study of endoplasmic reticulum stress-induced neuronal death in rat cultured hippocampal and cerebellar granule neurons

Keywords: AD، بیماری آلزایمر; ABC, avidin–biotin–peroxidase complex; Aβ, amyloid β-peptide; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; ASK1, apoptosis signal-regulating kinase; CGN, cerebellar granule neurons; CHOP, C/EBP homologous protein; DAB, 3,3′-diaminobenzidin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Conformational diseases: An umbrella for various neurological disorders with an impaired ubiquitin–proteasome system

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid; CHIP, C-terminus of HSC-70-interacting protein; CREB, cyclic AMP-response element binding protein; DJ-1, mitogen dependent oncogene of 189 amino acids involved Ras-related

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Peripheral inflammatory mechanisms modulate microglial activation in response to mild impairment of oxidative metabolism

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; BSA, bovine serum albumin; CNS, central nervous system; DAB, 3,3′-diaminobenzidine; EAE, experimental autoimmune encephalomyelitis; EAN, experimental autoimmune neuritis; IFN-γ, Interferon-gamma; KPBS, potassium phosphate buffered

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

A genome wide analysis of ubiquitin ligases in APP processing identifies a novel regulator of BACE1 mRNA levels

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; APP, β-amyloid precursor protein; Aβ, amyloid β peptideAlzheimer's; BACE1 regulation; PPIL2; hCyp-60; siRNA screen

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Neuroinflammation and regeneration in the early stages of Alzheimer's disease pathology

Keywords: AD، بیماری آلزایمر; Amyloid β; Alzheimer's disease; Cell cycle; Microglia; Neuroinflammation; RegenerationAβ, amyloid β; ACT, α1-antichymotrypsin; AD, Alzheimer's disease; ApoE, apolipoprotein E; APP, amyloid precursor protein; CNS, central nervous system; COX-2, cyclooxygen

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

PEGylated phospholipid nanomicelles interact with β-amyloid(1–42) and mitigate its β-sheet formation, aggregation and neurotoxicity in vitro

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; APP, amyloid precursor protein; Aβ, beta-amyloid; CD, circular dichroism; CMC, critical micellar concentration; CR, Congo red; DSPE-PEG2000, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000); EM,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Characterization of human Enah gene

Keywords: AD، بیماری آلزایمر; Enah, enabled homolog; Mena, mammalian enabled; Ena, enabled; βAPP, amyloid precursor protein; AD, Alzheimer's Disease; VASP, enabled/vasodilator-stimulated phosphoprotein; EVL, Ena/VASP-like protein; EVH, Ena/VASP homology; SH3, Src homology 3; RACE, rap

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Unsafe rear-end collision avoidance in Alzheimer's disease

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; NVA, near visual acuity; FVA, far visual acuity; CS, contrast sensitivity; SFM, structure from motion; UFOV, useful field of view; JLO, judgment of line orientation; CFT, complex figure test; BVRT, Benton visual retention test; TM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Early melatonin supplementation alleviates oxidative stress in a transgenic mouse model of Alzheimer's disease

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; BBB, brain–blood barrier; CSF, cerebrospinal fluid; Aβ, β-amyloid; DTNB, 5′,5′-dithiobis-2-nitrobenzoic acid; TBARS, thiobarbituric acid-reactive substances; SOD, superoxide dismutase; PBS, phosphate-buffered saline; PUFA, polyuns

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Changes of the cortex proteome and Apolipoprotein E in transgenic mouse models of Alzheimer's Disease

Keywords: AD، بیماری آلزایمر; Aβ, amyloid β; APP, Amyloid Precursor Protein; AD, Alzheimer's disease; ApoE, Apolipoprotein E; CSF, cerebrospinal fluid; DRP-2, dihydropyrimidinase-related protein-2; 2DE, two-dimensional electrophoresis; MS, mass spectrometry; MS/MS, tandem mass spectro

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

TRPC1 protects human SH-SY5Y cells against salsolinol-induced cytotoxicity by inhibiting apoptosis

Keywords: AD، بیماری آلزایمر; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson's disease; MAOB, Monoamine oxidase B; AD, Alzheimer's disease; SOCE, Store-operated calcium entry; Cch, carbachol; Tg, thapsigarginSalsolinol; Carbachol; Thapsigargin; Apoptosis; Neuroprote

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity

Keywords: AD، بیماری آلزایمر; Aβ, amyloid-beta peptide; PrP, prion peptide; AD, Alzheimer's disease; ER, endoplasmic reticulum; GRP78, glucose-regulated protein 78; Indo-1/AM, Indo-1 acetoxymethyl ester; IP3R, inositol 1,4,5-triphosphate receptor; PrD, Prion disorders; ROS, reactive o

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Cellular mechanism of U18666A-mediated apoptosis in cultured murine cortical neurons: Bridging Niemann–Pick disease type C and Alzheimer's disease

Keywords: AD، بیماری آلزایمر; Aβ, β-amyloid; AD, Alzheimer's disease; APP, amyloid precursor protein; CHO, Chinese hamster ovary; CoA, coenzyme A; ER, endoplasmic reticulum; HMG-CoA, 3-hydroxy-3-methylglutaryl coenzyme A; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Differentially expressed cortical genes contribute to perivascular deposition in transgenic mice with inducible neuron-specific expression of TGF-β1

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; A2m, α-2-macroglobulin; ApoE, apolipoprotein E; APP, amyloid precursor protein; CamKIIα, calcium/calmodulin kinase IIα; Cldn5, claudin 5; Ctla2, cytotoxic T lymphocyte-associated protein 2 alpha; Ctss, cathepsin S; CSF, cerebrospi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Mapping of Interaction Domains Mediating Binding between BACE1 and RTN/Nogo Proteins

Keywords: AD، بیماری آلزایمر; BACE1; RTN; Nogo; reticular; amyloid peptideAPP, amyloid precursor protein; AD, Alzheimer's disease; RHD, reticulon homology domain; TM, transmembrane; co-IP, co-immunoprecipitate(ion); ER, endoplasmic reticulum

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms

Keywords: AD، بیماری آلزایمر; Aβ, amyloid-β; AD, Alzheimer's disease; APP, β-amyloid precursor protein; BACE, β-site APP cleaving enzyme; COX, cycloxigenase; iNOS, inducible nitric oxide synthase; MEF, mouse embryonic fibroblasts; NSAIDs, Non-steroidal antiiflammatory drugs; PPAR-γ, p

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Aβ42 is More Rigid than Aβ40 at the C Terminus: Implications for Aβ Aggregation and Toxicity

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, amyloid β; NOE, nuclear Overhauser enhancement; HSQC, heteronuclear single quantum coherence; CSI, chemical shift indexAlzheimer's disease; NMR; Aβ toxicity; dynamics; Aβ aggregation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Four subgroups of Alzheimer's disease based on patterns of atrophy using VBM and a unique pattern for early onset disease

Keywords: AD، بیماری آلزایمر; NFTs, neurofibrillary tangles; AD, Alzheimer's disease; MRI, magnetic resonance imaging; VBM, voxel-based morphometry; PCC, posterior cingulate cortex; PrCC, precuneal cortex; MMSE, Mini-Mental State Examination; MCI, mild cognitive impairment; NINCDS, Na

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Amyloid β peptide (25–35) activates protein kinase C leading to cyclooxygenase-2 induction and prostaglandin E2 release in primary midbrain astrocytes

Keywords: AD، بیماری آلزایمر; Aβ, amyloid β; AD, Alzheimer's disease; APP, amyloid precursor protein; COX, cyclooxygenase; NSAIDs, non-steroidal anti-inflammatory drugs; PG, prostaglandin; PKC, protein kinase CAlzheimer's disease; Aβ25–35; Astroglia; CNS; Non-steroidal anti-inflammato

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Decreased phosphatidylethanolamine binding protein expression correlates with Aβ accumulation in the Tg2576 mouse model of Alzheimer's disease

Keywords: AD، بیماری آلزایمر; Aβ, amyloid β peptide; AD, Alzheimer's disease; APP, amyloid protein precursor; BCIP, 5-bromo-4-chloro-3-indolyl-phosphate; CT, C-terminal; DAB, diaminobenzidine; HCNP, hippocampal cholinergic neurostimulating peptide; NBT, nitroblue tetrazolium chloride;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Anti-Parkinsonian agents have anti-amyloidogenic activity for Alzheimer's β-amyloid fibrils in vitro

Keywords: AD، بیماری آلزایمر; Aβ, amyloid β-peptide; AD, Alzheimer's disease; Bro, bromocriptine; Cat, catechin; Cur, curcumin; DMSO, dimethyl sulfoxide; EC50, effective concentrations at 50% value; epi-Cat, epicatechin; fAβ, β-amyloid fibrils; Kmp, kaempferol; l-Dopa, levodopa; MAO-B

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Solution 1H NMR investigation of Zn2+ and Cd2+ binding to amyloid-beta peptide (Aβ) of Alzheimer's disease

Keywords: AD، بیماری آلزایمر; Aβ, amyloid-β peptide; AD, Alzheimer's disease; CD, circular dichroism; CSF, cerebrospinal fluid; NMR, Nuclear Magnetic ResonanceZinc; Spectroscopy; Structure; CD; Aggregation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Structural Differences in Aβ Amyloid Protofibrils and Fibrils Mapped by Hydrogen Exchange – Mass Spectrometry with On-line Proteolytic Fragmentation

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; APP, amyloid precursor protein; HX-MS, hydrogen-deuterium exchange-mass spectrometry; D, deuterium; CLC, calmidazolium chloride; ESI, electrospray ionization; LCamyloid fibrils; protofibrils; hydrogen-deuterium exchange; mass spec

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

The plasma membrane redox system in aging

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; ARE, antioxidant response element; CoQ, coenzyme Q; CR, calorie restriction; ETS, electron transport system; GSH, glutathione; HNE, 4-hydroxy-2,3-trans-nonenal; NIDDM, non-insulin-dependent diab

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

U18666A-mediated apoptosis in cultured murine cortical neurons: Role of caspases, calpains and kinases

Keywords: AD، بیماری آلزایمر; Aβ, β-amyloid; AD, Alzheimer's disease; AFC, aminotrifluoromethylcoumarin; ANOVA, analysis of variance; DAVID, Database for Annotation, Visualization, and Integrated Discovery; ER, endoplasmic reticulum; GSK3, glycogen synthase kinase 3; MAPK, mitogen-act

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Soluble oligomers of amyloid-β peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway

Keywords: AD، بیماری آلزایمر; Aβ, amyloid-β peptide; AD, Alzheimer's disease; AA, arachidonic acid; A-SMase, acidic sphingomyelinase; cPLA2, cytosolic calcium-dependent phospholipase A2; DAPI, 4,6-diamidino-2-phenylindole; DMEM, Dulbecco's modified Eagle's medium; MAFP, methyl arachid

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Oxidative modification of proteins in the frontal cortex of Alzheimer's disease brain

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; AAT, aspartate aminotransferase; βA, beta-amyloid; CA, carbonic anhydrase; 2D, two-dimensional; 2-DE, two-dimensional gel electrophoresis; DNP, dinitrophenyl; DNPH, 2,4-dinitrophenyl hydrazine; NFT, neurofibrillary tangle; GDH, gl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; FAD, familial form of Alzheimer's disease; Aβ, amyloid β-peptide; APP, amyloid precursor protein; PS, presenilin; ER, endoplasmic reticulum; IP3, inositol 1,4,5-trisphosphate; Bk, bradykinin; Hist, histamine; Cch, carbachol; Tg, t

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Cholesterol dysfunction in neurodegenerative diseases: Is Huntington's disease in the list?

Keywords: AD، بیماری آلزایمر; CNS, central nervous system; HD, Huntington's disease; 24-OH-Chol, 24S-hydroxycholesterol; ApoE, apolipoprotein E; SLOS, Smith–Lemli–Opitz syndrome; AD, Alzheimer's disease; Aβ, beta-amyloid; NPC, Niemann–Pick disease; HIP14, huntingtin interacting protei

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Dysregulation of tau phosphorylation is a hypothesized point of convergence in the pathogenesis of alzheimer's disease, frontotemporal dementia and schizophrenia with therapeutic implications

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; apoE, apolipoprotein E; apoER2, apolipoprotein E type 2 receptors; APP, amyloid precursor protein; CDK-5, cyclin-dependent protein kinase-5; CHO, Chinese hamster ovary cells; CNR1, cadherin-related neuronal receptor protein; CpG,

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Increase in apoptosis with neural differentiation and shortening of the lifespan of P19 cells overexpressing tau

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; DTT, dithiothreitol; LTD, long-term depression; LTP, long-term potentiation; NPM, nucleophosmin; P19wt, P19 wild-type cells; P19tau, P19 cells overexpressing human tau441; PHFs, paired helical filaments; RA, retinoic acid; RAR, re

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Amyloid-β Peptide Disruption of Lipid Membranes and the Effect of Metal Ions

Keywords: AD، بیماری آلزایمر; amyloid Aβ; peptide–Lipid interactions; membranes; solid-state NMR; structureAβ, β-amyloid peptide; AD, Alzheimer's disease; APP, amyloid precursor protein; CD, circular dichroism spectroscopy; CSA, chemical shift anisotropy; CuGly2, copper glycine; DPH,

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Linker Histone H1 Binds to Disease Associated Amyloid-like Fibrils

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; PD, Parkinson's disease; Aβ, amyloid-β; PICUP, photo-induced cross-linking of unmodified proteins; EM, electron microscopy; TOSYL, p-toluenesulfonate; SPR, surface plasmon resonance; NFTs, intraneuronal neurofibrillary tanglesamyl

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Amino-terminal Domain Stability Mediates Apolipoprotein E Aggregation into Neurotoxic Fibrils

Keywords: AD، بیماری آلزایمر; AB, 100 mM NH4HCO3 (pH 7.8); apo, apolipoprotein; AD, Alzheimer's disease; APP, amyloid precursor protein; CSF, cerebrospinal fluid; GFAP, glial fibrillary acidic protein; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PBS, 135 mM NaCl

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade

Keywords: AD، بیماری آلزایمر; Acetylcholinesterase; Alzheimer's disease; Cortical culture; Glutamate; Nicotinic acetylcholine receptor; NeurotoxicityAChE, acetylcholinesterase; AD, Alzheimer's disease; Aβ, amyloid β protein; CNS, central nervous system; DHβE, dihydro-β-erythroidine; d

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Microglia induce neural cell death via a proximity-dependent mechanism involving nitric oxide

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; COX, Cyclooxygenase; FBS, fetal bovine serum; IFN, Interferon; ICC, Immunocytochemistry; iNOS, inducible nitric oxide synthase; LPS, Lipopolysaccharide; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NaNO2, nit

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2006 سفارش ترجمه

“The seven sins” of the Hebbian synapse: Can the hypothesis of synaptic plasticity explain long-term memory consolidation?

Keywords: AD، بیماری آلزایمر; αCaMKII, α-calcium-calmodulin kinase II; AD, Alzheimer's disease; CPEB, cytoplasmic polyadenelation element binding protein; CRE, cAMP-response element; CREB, cAMP response element-binding protein; EST, electroshock therapy; LTP, long-term potentiation; M

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2006 سفارش ترجمه

Nerve growth factor in treatment and pathogenesis of Alzheimer's disease

Keywords: AD، بیماری آلزایمر; NGF, nerve growth factor; AChE, acetyl choline esterase; ChAT, choline acetyl transferase; BFCNs, basal forebrain cholinergic neurons; AD, Alzheimer's disease; CNS, central nervous system; MMSE, minimental state examination; MCI, mild cognitive impairment

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2006 سفارش ترجمه

Modulating apoptosis as a target for effective therapy

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; DR, death receptor; HD, Huntington's disease; IAPs, inhibitor of apoptosis proteins; IDDM, insulin-dependent diabetes mellitus; ND, neurodegenerative diseases; NODm, non-obese diabetic mice; PD,

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2006 سفارش ترجمه

Pattern of cerebral hypoperfusion in Alzheimer's disease and mild cognitive impairment measured with arterial spin-labeling MR imaging: Initial experience

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; CN, cognitively normal; FDG, fluorodeoxyglucose; HMPAO, hexamethylpropyleneamine oxime; MCI, mild cognitive impairment; PVE, partial volume effect

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2006 سفارش ترجمه

The cell cycle as a therapeutic target for Alzheimer's disease

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; APP, amyloid precursor protein; APP-BP1, APP binding protein 1; cdk, cyclin-dependent kinase; CSN, Cop9 signalosome; FAD, familial AD; JNK3, c-Jun N-terminal kinase 3; NSAID, nonsteroidal anti-inflammatory drug; PAK3, p21-activate

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2006 سفارش ترجمه

Citrullination: A posttranslational modification in health and disease

Keywords: AD، بیماری آلزایمر; ACPA, anti-citrullinated protein/peptide antibody; AD, Alzheimer's disease; AKA, anti-keratin antibody; AFA, anti-filaggrin antibody; APF, anti-perinuclear factor; cAMP, cyclic adenosine monophosphate; CIA, collagen induced arthritis; CNS, central nervous

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

Mechanisms of action of green tea catechins, with a focus on ischemia-induced neurodegeneration

Keywords: AD، بیماری آلزایمر; 3-HK, 3-hydroxykynurenine; 6-OHDA, 6-hydroxydopamine; AA, arachidonic acid; AAPH, 2,2′-azobis (2-amidinopropane) hydrochloride; AD, Alzheimer's disease; ALT, alanine aminotransferase; ARE, antioxidant response element; BBB, blood–brain barrier; C, (+)-cat

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

Zinc and copper: Pharmacological probes and endogenous modulators of neuronal excitability

Keywords: AD، بیماری آلزایمر; Zinc; Copper; Voltage-gated-like ion channels; Neuronal excitability; Epilepsy; Alzheimer's diseaseAβ, amyloid-β protein; AD, Alzheimer's disease; AMPA, (S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; Ca2+, calcium; CNS, central nervous sys

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2006 سفارش ترجمه