دانلود مقالات ISI درباره Adme, Absorption, Distribution, Metabolism, Excretion + ترجمه فارسی

بازخرید یک داربست دارویی: شناسایی آنالوگهای جدید سیلورس ریمونوبانت به عنوان عوامل ضد تومورال قوی

Repurposing of a drug scaffold: Identification of novel sila analogues of rimonabant as potent antitubercular agents

Keywords: Drug repurposing; Tuberculosis; Rimonabant; BM212; Sila analogue; MmpL3 inhibitorMIC, Minimum Inhibitory Concentration; ADME, absorption, distribution, metabolism, excretion; CB1, Cannabinoid receptor Type 1; Mtb, Mycobacterium tuberculosis; CNS, Central

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

نقش گلوکورونیزاسیون در مقاومت دارویی

The role of glucuronidation in drug resistance

Keywords: UGT-dependent resistance; Glucuronidation; ABC transporters; Antitumor drug resistance; UGT-modulated pharmacokineticsABC, ATP-binding cassette; ADME, absorption, distribution, metabolism, excretion; AED, antiepileptic drug; AhR, aryl hydrocarbon receptor

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

دوز تکرار 28 روزه سمیت خوراکی مونیلیورفین در موش صحرایی

Repeated dose 28-day oral toxicity study of moniliformin in rats

Keywords: ADME, absorption, distribution, metabolism, excretion; b.w., body weight; CL, chemiluminescence; ESI, electrospray ionisation; GHS, Globally Harmonized System; GI, gastrointestinal tract; HPLC, high performance liquid chromatography; i.g., intragastric; L

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes

Keywords: ADME, absorption, distribution, metabolism, excretion; CAR, constitutive androstane receptor (NR1I3); CITCO, 6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime; CYP, cytochrome P450; DMET, drug metabolism and transpor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Ru(II) dyads derived from α-oligothiophenes: A new class of potent and versatile photosensitizers for PDT

Keywords: PDT, photodynamic therapy; PS, photosensitizer; PS*, excited state photosensitizer; ROS, reactive oxygen species; 1Δg, singlet oxygen; 1O2, singlet oxygen; O2, oxygen; ADME, absorption, distribution, metabolism, excretion; bpy, 2,2′-bipyridine; dppn, benz

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

A mass balance approach for calculation of recovery and binding enables the use of ultrafiltration as a rapid method for measurement of plasma protein binding for even highly lipophilic compounds

Keywords: ADME, absorption, distribution, metabolism, excretion; ED, equilibrium dialysis; EP, eppendorf; NSB, non-specific binding; PD, pharmacodynamics; PK, pharmacokinetics; PPB, plasma protein binding; RED, rapid equilibrium dialysis; UF, ultrafiltrationPlasma

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Role of iodine in the toxicity of diiodomethyl-p-tolylsulfone (DIMPTS) in rats: ADME

Keywords: AAALAC, Association for Assessment and Accreditation of Laboratory Animal Care; ADME, absorption, distribution, metabolism, excretion; AUC, area under the plasma concentration time curve; DIMPTS, diiodomethyl-p-toylsulfone; F-344, Fischer 344 rats; FCW, f

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Improvement of a capillary electrophoresis/frontal analysis (CE/FA) method for determining binding constants: Discussion on relevant parameters

Keywords: ACE, Affinity capillary electrophoresis (mobility shift assay); ADME, Absorption, distribution, metabolism, excretion; BGE, Background electrolyte; BSA, Bovine serum albumin; CE, Capillary electrophoresis; CE/FA, Capillary electrophoresis/frontal analysis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

The role of nuclear receptors in pharmacokinetic drug–drug interactions in oncology

Keywords: ABC, ATP-binding cassette; ADME, absorption, distribution, metabolism, excretion; APC, 7-ethyl-10-[4-N-(5-aminopentanoic acid)1-piperidino]carbonyloxycamptothecin; CAM, complementary alternative medicines; (h)CAR, (human) constitutive androstane receptor;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

The role of the human ABCG2 multidrug transporter and its variants in cancer therapy and toxicology

Keywords: aa, amino acid; ABC transporters, ATP binding cassette transporters; ABCP, placenta-specific ABC protein; ADME, absorption, distribution, metabolism, excretion; BCRP, breast cancer resistance protein; HSC, hematopoietic stem cell; MDR, human multidrug res

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه