دانلود مقالات ISI درباره ADR، واکنش نامطلوب دارو + ترجمه فارسی

اثر اکسیدوئدون / نالوکسون طولانی مدت در مدیریت درد پس از عمل پس از جابجایی کامل زانو: یک مطالعه غیرمعمول در آینده

Effect of prolonged-released oxycodone/naloxone in postoperative pain management after total knee replacement: a nonrandomized prospective trial

Keywords: ADR، واکنش نامطلوب دارو; OXN, oxycodone/naloxone; TKR, total knee replacement; HSS score, Hospital for Special Surgery score; BFI, Bowel Function Index; BPI-SF, Brief Pain Inventory Short Form; ADR, adverse drug reaction; SADR, serious adverse drug reaction; SD, standard deviatio

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

مدولاسیون حمل و نقل توسط داروهای گیاهی چینی و متابولیسم داروهای خوراکی دارویی

Transporter modulation by Chinese herbal medicines and its mediated pharmacokinetic herb–drug interactions

Keywords: ADR، واکنش نامطلوب دارو; ADR, adverse drug reaction; ABC, ATP-binding cassette; AUC, area under plasma concentration versus time curve; BCRP, breast cancer resistance protein; CAR, constitutive androstane receptor; CE, capillary electrophoresis; CHM, Chinese herbal medicine; CL,

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

افزایش ظرفیت ایمنی واکسن در سطح جهانی: چشم انداز چرخه زندگی

Enhancing vaccine safety capacity globally: A lifecycle perspective

Keywords: ADR، واکنش نامطلوب دارو; ACIP, Advisory Committee on Immunization Practices; ADR, Adverse Drug Reaction; ADVANCE, Accelerated Development of VAccine beNefit-risk Collaboration in Europe; AEFI, adverse events following immunizations; aP, acellular pertussis; AVAREF, African Vaccin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The value of integrating pre-clinical data to predict nausea and vomiting risk in humans as illustrated by AZD3514, a novel androgen receptor modulator

Keywords: ADR، واکنش نامطلوب دارو; ADR, adverse drug reaction; AE, adverse effect; AR, androgen receptor; AUC, area under the curve; DRF, dose range finding; FITH, first in time in human; GI, gastrointestinal; MTD, maximum tolerated doseNausea; Vomiting; Pre-clinical animal models; Transla

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Cytochrome P450 expression system for high-throughput real-time detection of genotoxicity: Application to the study of human CYP1A2 variants

Keywords: ADR، واکنش نامطلوب دارو; 1AP, 1-aminopyrene; 2AA, 2-aminoanthracene; ADMET, absorption, distribution, metabolism, excretion and toxicity; ADR, adverse drug reaction; CPR, cytochrome P450 oxidoreductase; δ-Ala, δ-aminolevulinic acid; DMEs, drug metabolizing enzymes; FI, Induction

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

CYP2C9, VKORC1, CYP4F2, ABCB1 and F5 variants: Influence on quality of long-term anticoagulation

Keywords: ADR، واکنش نامطلوب دارو; OAC, oral anticoagulant; ADR, adverse drug reaction; BMI, body mass index; SD, standard deviation; CI, confidence interval; BSA, body surface area; INR, international normalized ratio; AOD, arterial occlusive disease; CAD, coronary artery disease; AVR, ao

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Identification and quantification of drug–albumin adducts in serum samples from a drug exposure study in mice

Keywords: ADR، واکنش نامطلوب دارو; ACN, acetonitrile; ADR, adverse drug reaction; ALAT, alanine aminotransferase; APAP, acetaminophen; ASAT, aspartate aminotransferase; BSA, bovine serum albumin; cys34, cysteine on position 34; cys579, cysteine on position 579; DTT, dithiothreitol; EIC, ex

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Reconstitution of the interplay between cytochrome P450 and human glutathione S-transferases in clozapine metabolism in yeast

Keywords: ADR، واکنش نامطلوب دارو; ADR, adverse drug reaction; CYP, cytochrome P450; hGST, human glutathione S-transferase; GSH, glutathione; BM3 M11, cytochrome P450 BM3 M11 mutant; mETC, mitochondrial electron transport chain; ROS, reactive oxygen species; CDNB, 1-chloro-2,4-dinitrobenze

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Drug-induced severe adverse reaction enhanced by human herpes virus-6 reactivation

Keywords: ADR، واکنش نامطلوب دارو; ADR, adverse drug reaction; DIHS, drug-induced hypersensitivity syndrome; DILI, drug-induced liver injury; DRESS, drug reaction with eosinophilia and systemic symptoms; HCMV, human cytomegalovirus; HHV, human herpes virus; HSR, hypersensitivity reactions;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

A critical reappraisal of the current data on drug-induced linear immunoglobulin A bullous dermatosis: A real and separate nosological entity?

Keywords: ADR، واکنش نامطلوب دارو; ADR, adverse drug reaction; CDR, challenge-dechallenge-rechallenge; CI, confidence interval; DIF, direct immunofluorescence; LABD, linear IgA bullous dermatosis; LAD, linear IgA disease; OR, odds ratio; VILAD, vancomycin-induced linear IgA disease

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

State of the art in benefit–risk analysis: Medicines

Keywords: ADR، واکنش نامطلوب دارو; ADR, adverse drug reaction; BR, benefit–risk; CHMP, Committee for Medicinal Products for Human use; EC, European Commission; EMA, European Medicines Agency; EU, European Union; EudraVigilance, European Union Drug Regulating Authorities Pharmacovigilance;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Genetic and immune predictors for hypersensitivity syndrome to antiepileptic drugs

Keywords: ADR، واکنش نامطلوب دارو; ADR, adverse drug reaction; AED, antiepileptic drug; CBZ, carbamazepine; DIHS, drug-induced hypersensitivity syndrome; DILI, drug-induced liver injury; DRESS, drug rash with eosinophilia and systemic symptoms; Fas, CD95, APO-I; HLA, human leukocyte antige

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Emerging real-time technologies in molecular medicine and the evolution of integrated ‘pharmacomics’ approaches to personalized medicine and drug discovery

Keywords: ADR، واکنش نامطلوب دارو; ADR, adverse drug reaction; cDNA, complementary DNA; ChIP, chromatin immunoprecipitation; PCR, polymerase chain reaction; SMRT, single molecule real-time; SNP, single nucleotide polymorphismReal-time sequencing; Next generation sequencing; Pharmacomics; M

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

An Update on Drug-induced Liver Injury

Keywords: ADR، واکنش نامطلوب دارو; hepatotoxicity; liver injury; DILI; causality; drug-inducedDILI, idiosyncratic drug-induced liver injury; NRH, nodular regenerative hyperplasia; ADR, adverse drug reaction; RUCAM, Roussel Uclaf Causality Assessment Method; INH, isoniazid; RIF, rifampicin;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Abrogation of nimesulide induced oxidative stress and mitochondria mediated apoptosis by Fumaria parviflora Lam. extract

Keywords: ADR، واکنش نامطلوب دارو; Ψm, mitochondrial membrane potential; ADR, adverse drug reaction; AIF, apoptosis inducing factor; ApoAF-1, apoptosis activating factor-1; BHA, butylated hydroxyanisole; BHT, butylated hydroxytoluene; CAD, caspases activated DNase; CMF, chloromethylfluores

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Clinical course and outcomes of drug-induced liver injury: Nimesulide as the first implicated medication

Keywords: ADR، واکنش نامطلوب دارو; ADR, adverse drug reaction; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; DILI, drug-induced liver injury; NAFLD, non-alcoholic fatty liver disease; NSAIDs, non-steroidal anti-inflammatory drugs; OLT, orthotopi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

The validation of an invitro colonic motility assay as a biomarker for gastrointestinal adverse drug reactions

Keywords: ADR، واکنش نامطلوب دارو; ADR, adverse drug reaction; AUC, area under curve; CPMCs, colonic peristaltic motor complexes; EFTPCmax, maximal effective free therapeutic plasma concentration; FP, false positive; GADRs, gastrointestinal adverse drug reactions; l-NAME, N-omega-nitro-l-a

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Ibuprofen-induced hypersensitivity syndrome

Keywords: ADR، واکنش نامطلوب دارو; ADR, adverse drug reaction; AUC, area under the concentration-time curve; Cmax, maximum plasma concentration; CoA, coenzyme A; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; CYP, cytochrome P450; HSRs, hypersensitivity reactions; NSAID, nonsteroidal an

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2010 سفارش ترجمه

TaqMan real-time PCR quantification strategy of CYP2D6 gene copy number for the LightCycler 2.0

Keywords: ADR، واکنش نامطلوب دارو; CYP, Cytochrome P450; ADR, Adverse drug reaction; GCN, Gene copy number; PPV, Positive predictive value; NPV, Negative predictive value; FAM, Fluorescein; HEX, HexachlorofluoresceinCYP2D6; Gene copy number; TaqMan real-time PCR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Prevalence of drug–drug interactions at hospital entry and during hospital stay of patients in internal medicine

Keywords: ADR، واکنش نامطلوب دارو; ACE, Angiotensin-converting enzyme; ADR, Adverse drug reaction; ATC, Anatomical therapeutical chemical; CYP, Cytochrome P450 isozyme; (p)DDI, (Potential) drug–drug interaction; ICD-10, International classification of diseases, 10th revision; MAO, Monoamin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

The ITPA c.94C > A and g.IVS2 + 21A > C sequence variants contribute to missplicing of the ITPA gene

Keywords: ADR، واکنش نامطلوب دارو; ITPA; ITPase, Inosine triphosphate pyrophosphatase; Azathioprine; ADR, Adverse drug reaction; Pharmacogenetic; Cryptic 5′ splice site; Missplicing

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Effect of zolpidem on sleep architecture and its next-morning residual effect in insomniac patients: A randomized crossover comparative study with brotizolam

Keywords: ADR، واکنش نامطلوب دارو; ADR, adverse drug reaction; ANOVA, analysis of variance; BTM, brotizolam; BZD, benzodiazepine; ICSD, International Classification of Sleep Disorders; NBZD, non-benzodiazepine; PPI, psychophysiological insomnia; PSG, polysomnography; SL, sleep latency; SLT

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه