Keywords: آلدو کتو ردوکتاز; AKR; aldo-keto reductase; CBZ-E; carbamazepine 10,11-epoxide; Cmax; mean maximum level; CLint; internal clearance; DHD; 10,11-dihydro-10,11-dihydroxy-carbamazepine; MHD; 10,11-dihydro-10-hydroxy-carbamazepine; SDR; short-chain dehydrogenase/reductase; O
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Identification of a determinant for strict NADP(H)-specificity and high sensitivity to mixed-type steroid inhibitor of rabbit aldo-keto reductase 1C33 by site-directed mutagenesis
Keywords: آلدو کتو ردوکتاز; 5αAD; 5α-androstane-3α,17β-diol; AKR; aldo-keto reductase; DOC; deoxycorticosterone; HSD; hydroxysteroid dehydrogenase; P3A; pyridine-3-aldehyde; Aldo-keto reductase; Bile acid synthesis; Coenzyme specificity determinant; Conformational change; De
1-Heteroaryl-3-phenoxypropan-2-ones as inhibitors of cytosolic phospholipase A2α and fatty acid amide hydrolase: Effect of the replacement of the ether oxygen with sulfur and nitrogen moieties on enzyme inhibition and metabolic stability
Keywords: آلدو کتو ردوکتاز; Cytosolic phospholipase A2α; Fatty acid amide hydrolase; Indole-5-carboxylic acid; Benzotriazole; Inhibitors; Metabolic stability; Cytochrome P450; Carbonyl reductase; Short chain dehydrogenase/reductase; Aldo-keto reductase;
Aldo-keto reductase 7A5 (AKR7A5) attenuates oxidative stress and reactive aldehyde toxicity in V79-4 cells
Keywords: آلدو کتو ردوکتاز; AKR; aldo-keto reductase; ROS; reactive oxygen species; DCFH/DA; 2â²7â²-dichlorodihydrofluorescein diacetate; AFB1; aflatoxin B1; CDNB; 1-chloro-2,4-dintrobenzene; MTT; 3-(4,5-dimethylthiazoyl-2-yl)-2,5-diphenyltetrazolium bromide; H2O2; hydrogen pero
Two types of alcohol dehydrogenase from Perilla can form citral and perillaldehyde
Keywords: آلدو کتو ردوکتاز; Perilla; Labiatae; Aldo-keto reductase; Geraniol dehydrogenase; Geraniol; Citral; Sequential enzymatic reaction; Biosynthetic pathway; Essential oil;
Characterization and identification of three novel aldo-keto reductases from Lodderomyces elongisporus for reducing ethyl 4-chloroacetoacetate
Keywords: آلدو کتو ردوکتاز; Lodderomyces elongisporus; Aldo-keto reductase; Characterization; Identification; Ethyl 4-chloroacetoacetate;
Identification, characterization, and crystal structure of an aldo-keto reductase (AKR2E4) from the silkworm Bombyx mori
Keywords: آلدو کتو ردوکتاز; Crystal structure; Enzyme specificity; NADH; NADPH; Lepidoptera; 3DE; 3-dehydroecdysone; AKR; aldo-keto reductase; DLG; dl-glyceraldehyde; GST; glutathione transferase; PCR; polymerase chain reaction; RT-PCR; reverse transcriptase PCR; SDS-PAGE; sodiu
Characterization of rabbit morphine 6-dehydrogenase and two NAD+-dependent 3α(17β)-hydroxysteroid dehydrogenases
Keywords: آلدو کتو ردوکتاز; Aldo-keto reductase; Morphine 6-dehydrogenase; 3α/17β-hydroxysteroid dehydrogenase; Flavonoids; Substrate recognition;
Human aldo-keto reductase AKR7A2 protects against the cytotoxicity and mutagenicity of reactive aldehydes and lowers intracellular reactive oxygen species in hamster V79-4 cells
Keywords: آلدو کتو ردوکتاز; AKR; aldo-keto reductase; SSA; succinic semialdehyde; CBA; carboxybenzaldehyde; IC50; inhibitory concentration of 50% the cells; HNE; 4-hydroxynonenal; MTT; 3-(4,5-dimethylthiazoyl-2-yl)-2,5-diphenyltetrazolium bromide; NQ; naphthoquinone; HGPRT; hypoxa
Stereospecific reduction of a potent kinesin spindle protein (KSP) inhibitor in human tissues
Keywords: آلدو کتو ردوکتاز; AKRs; aldo-keto reductases; HSD; hydroxysteroid dehydrogenase; I.S.; an internal standard; KSP; kinesin spindle protein; NADPH_R; NADPH regeneration system; SDRs; short-chain dehydrogenases/reductases; Ketone reduction; Stereospecificity; Cofactor depen
Liquid chromatography-mass spectrometry (LC-MS) of steroid hormone metabolites and its applications
Keywords: آلدو کتو ردوکتاز; 3α-Diol-17G; 3α-hydroxy-5α-androstane-17β-glucuronide; 3β-Diol-17G; 3β-hydroxy-5α-androstane-17β-glucuronide; 3α-Diol-17S; 3α-hydroxy-5α-androstane-17β-sulfate; 3β-Diol-17S; 3β-hydroxy-5α-androstane-17β-sulfate; DHT; dihydrotestosterone; D
Role of human aldo-keto-reductase AKR1B10 in the protection against toxic aldehydes
Keywords: آلدو کتو ردوکتاز; DEPT; distortionless enhancement by polarization transfer; 4-HNE; (2E)-4-hydroxynon-2-enal; HPLC; high-pressure liquid chromatography; 4-MP; 4-methylpentanal; 4-ONE; (2E)-4-oxonon-2-enal; TLC; thin layer chromatography; TMS; tetramethylsilane; Aldo-keto
The structure of Apo R268A human aldose reductase: Hinges and latches that control the kinetic mechanism
Keywords: آلدو کتو ردوکتاز; NADP+; nicotinamide adenosine diphosphate 2â²-phosphate (oxidized); NADPH; nicotinamide adenosine diphosphate 2â²-phosphate (reduced); AKR; aldo-keto reductase; Aldose reductase; Apo structure; Loop movement; X-ray structure; Enzyme kinetics;