Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ACh, acetylcholine; AChE, acetylcholinesterase; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Aβ, amyloid beta; BChE, butyrylcholinesterase; DMPD, N,N-dimethyl-p-phenylendiamine; DMSO, dimethyl sulfoxide; DPPH, 2,2-diphenyl-1-picrylhydrazyl
مقالات ISI ALS، اسکلروز جانبی جانبی آمیوتروفی (ترجمه نشده)
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Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; α/β-SNAP, α/β soluble NSF attachment proteins; ALS, amyotrophic lateral sclerosis; BoNt-C1, Botulinum Neurotoxin C1; β-Tub III, β-Tubulin III; [Ca2 +]c, cytosolic calcium concentration; CaMK-II, Ca2 +/calmodulin-dependent protein kinase II; dl-TBOA, dl-th
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; Aβ, amyloid beta; AD, Alzheimer’s disease; Akt, protein kinase B; ALS, amyotrophic lateral sclerosis; AP-1, activator protein-1; BBB, blood brain barrier; BDNF, brain-derived neurotropic factor; CB, cannabinoid; CBF, cerebral blood flow; CSF, cerebrospina
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AD, Alzheimer’s disease; ALS, amyotrophic lateral sclerosis; APP, amyloid precursor protein; BBB, blood-brain barrier; BSB, blood-spinal cord barrier; C1-Inh/C1-INH, C1 complex inhibitor; CNS, central nervous system; CR1, complement receptor 1; CR2, compl
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; APP, amyloid precursor protein; AS, α-synuclein; ASD, Autism spectrum disorder; ADK, adenosine kinase; ATP, adenosine triphosphate; AxD, Alexander disease; CD81, Cluster of Differentiation 81; C
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AD, Alzheimer’s disease; ALS, amyotrophic lateral sclerosis; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid; AMPAR, AMPA receptor; ADEM, acute disseminated encephalomyelitis; APP, amyloid precursor protein; CBD, cortico-basal degeneration; DH
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; Depression; Neurotoxicity; Pain; Seizure; Stroke; Traumatic brain injuryAD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; AMPA, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; AP-1, activator protein 1; ASD, autism spectrum disorder;
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; 6-OHDA, 6-hydroxydopamine; ABP, actin binding protein; AD, Alzheimer’s disease; ALS, amyotrophic lateral sclerosis; APP, amyloid precursor protein; Aβ, amyloid-β; Cdk5, cyclin-dependent kinase 5; CMT, Charcot-Marie-Tooth disease; CMT2, Charcot-Marie-Tooth
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AMPK, 5′ adenosine monophosphate-activated protein kinase; AD, Alzheimer's disease; ALS, Amyotrophic lateral sclerosis; BDPP, Bioactive dietary polyphenol preparation; BAT, Brown adipose tissue; CaMKKβ, Ca2+/CaM-dependent protein kinase kinase β; CREB, cA
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; ANOVA, analysis of variance; CCA, cortical cerebellar atrophy; CNS, central nerve system; DSM-IV, diagnostic and statistical manual of mental disorders, 4th edition; eZIS, easy Z-score imaging s
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; Brain-computer interfaces; RehabilitationAAC, augmentative and alternative communication; ALS, amyotrophic lateral sclerosis; BCI, brain-computer interface; CNS, central nervous system; EEG, electroencephalography; fMRI, functional magnetic resonance imag
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, amyotrophic lateral sclerosis; ALSFRS-R, ALS functional rating scale in its revised form; APB, abductor pollicis brevis muscle; BB, biceps brachii muscle; EI, echo intensity; EMG, electromyography; ER, extensor muscles of the forearm; MND, motor neur
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; Amyotrophic lateral sclerosis; Communication aids for disabled; Brain-computer interfaces; Language; Rehabilitation; Translational medical researchAAC, augmentative and alternative communication; ALS, amyotrophic lateral sclerosis; BCI, brain-computer int
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AFNI, analysis of functional neuroimages; ALS, amyotrophic lateral sclerosis; ALSFRS-R, amyotrophic lateral sclerosis rating scale; ANCOVA, analysis of covariance; BOLD, blood oxygen-level dependent; DTI, diffusion tensor imaging; Epi, echo planar imaging
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, amyotrophic lateral sclerosis; cAMP, cyclic adenosine monophosphate; dbcAMP, dibutyryl-cAMP; DMSO, dimethyl sulfoxide; hESCs, human embryonic stem cells; hPSCs, human pluripotent stem cell; HPRT1, hypoxanthine phosphoribosyltransferase 1; iPSCs, indu
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AD, Alzheimer׳s disease; Ala, alanine; ALS, amyotrophic lateral sclerosis; APP, amyloid precursor protein; APP/PS1, Aβ overexpressing mice APP (K670N/M671L) and PS1 (M146L) mutants; AppLon, London familial amyloid precursor protein mutation, APP (V717I);
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ACSF, artificial cerebrospinal fluid; ALS, amyotrophic lateral sclerosis; CH, cumene hydroperoxide; EGTA, ethyleneglycol-bis (2-aminoethylether)-N,N,N′,N′-tetra acetic acid; H2O2, hydrogen peroxide; HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic aci
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AANAT, aralkylamine N-acetyltransferase; Aβ, amyloid-β; AD, Alzheimer's disease; AFMK, N1-acetyl-N2-formyl-5-methoxykynuramine; AIM2, absent in melanoma 2; ALS, amyotrophic lateral sclerosis; AMK, N1-acetyl-5-methoxykynuramine; AMMC, 3-acetamidomethyl-6-m
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, amyotrophic lateral sclerosis; FALS, familial amyotrophic lateral sclerosis; SALS, sporadic amyotrophic lateral sclerosis; FTD, frontotemporal dementia; GWAS, genome-wide association study; SNP, single-nucleotide polymorphism; NGS, next generation se
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AAV, adeno-associated virus; ALS, amyotrophic lateral sclerosis; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ChAT, choline acetyltransferase; CHOP, C/EBP homologous protein; CMAP, compound muscle action potential; CNTF, ciliary neurotrophi
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, amyotrophic lateral sclerosis; CFP, complex fasciculation potential; fib-psw, fibrillation potential and positive sharp wave; FP, fasciculation potential; FVC, forced vital capacity; MUP, motor unit potential; PMA, progressive muscular atrophyAmyotro
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, amyotrophic lateral sclerosis; AMS, aggressive multiple sclerosis; AMSTC, allegheny multiple sclerosis treatment center; CI, conference interval; DMTs, disease modifying treatments; EDSS, Expanded Disability Status Scale; GA, glatiramer acetate; HR,
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; DA, dopaminergic; ER, endoplasmic reticulum; 4E-BP1, eukaryotic initiation factor 4E (eIF4E)-binding protein; HD, Huntington's disease; LRRK2, leucine-rich repeat kinase 2; MPTP, 1-methyl-4-phen
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; 2,4-D, 2,4-dichlorophenoxyacetic acid; 2,4,5-T, 2,4,5-trichlorophenoxyacetic acid; AD, Alzheimer disease; aOR, adjusted odds ratio; AhR, aryl hydrocarbon receptor; ALS, amyotrophic lateral sclerosis; BMI, body mass index; CI, confidence interval; CNS, cen
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AD, Alzheimer’s disease; ALS, amyotrophic lateral sclerosis; FTDP-17, frontotemporal degeneration with Parkinsonism linked to chromosome 17; HD, Huntington’s disease; MAP, microtubule-associated protein; MT, microtubules; MTOC, microtubule organizing cent
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, amyotrophic lateral sclerosis; FP, fasciculation potentials; HDsEMG, high density surface electromyography; MU, motor unit; PCA, principal component analysisAmyotrophic lateral sclerosis; Fasciculation potential; Feature extraction; Principal compone
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ABCA1, ATP-binding cassette transporter A1; ACAT, acyl-CoA:cholesterol acyltransferase; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; APOE, apolipoprotein E; BBB, blood–brain barrier; CEs, cholesterol esters; CJD, Creutzfeldt–Jakob disease;
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; Aβ, amyloid-β; ALS, amyotrophic lateral sclerosis; APP, amyloid precursor protein; BLG, Basso mouse scale/Ladder climb/Grid walk; BMS, Basso mouse scale; DAPT, N-[(3, 5-Difluorophenyl)acetyl]-l-alanyl-2-phenylglycine-1,1-dimethylethyl ester; DEA, diethyla
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AD, Alzheimer’s disease; ALS, amyotrophic lateral sclerosis; FBA, flux balance analysis; GABA, gamma-aminobutyric acid; HD, Huntington’s disease; KIV, ketoisovalerate; KLF, Krüppel-like factor; KMV, alpha-keto-beta-methylvalerate; MS, multiple sclerosis;
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AChE, acetylcholinesterase; ALS, amyotrophic lateral sclerosis; FG, Fluoro-Gold; GDNF, Glial-derived Neurotrophic Factor; MEPs, motor end platesMotor neurons; Motor end plates; Retrograde transport; Muscles; Fluoro-Gold; Mouse hindlimb
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; Arimoclomol; ALS; SOD1 mice; Heat shock response; Heat shock proteins; Neurodegeneration17-AAG, 17-N-Allylamino-17-demethoxygeldanamycin; ALS, Amyotrophic Lateral Sclerosis; ATF6, Activating transcription factor 6; BIP, Binding immunoglobulin protein; C9O
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; Alcohol; Microglia; Neuroinflammation; Behavior; Neurodegeneration; Animal modelsA(1)R, adenosine A(1) receptor; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; AP-1, activator protein-1; AQP4, aquaporin-4; ARG1, arginase 1; Aβ, β-amyloid; BD
Toward the validation of a new method (MUNIX) for motor unit number assessment
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ADM, abductor digiti minimi muscle; ALS, amyotrophic lateral sclerosis; CMAP, compound muscle action potential; IS-MUNE, incremental stimulation motor unit number estimation; MU, motor unit; MUAP, motor unit action potential; MUNE, motor unit number estim
Hydrogen peroxide-mediated induction of SOD1 gene transcription is independent from Nrf2 in a cellular model of neurodegeneration
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, Amyotrophic Lateral Sclerosis; ARE/EpRE, Antioxidant/Electrophile responsive Element; CEs, Composite Elements; fALS, familial Amyotrophic Lateral Sclerosis; NDs, Neurodegenerative Disorders; OS, Oxidative stress; PD, Parkinson's disease; PBMCs, Perip
Length-dependent axo-terminal degeneration at the neuromuscular synapses of type II muscle in SOD1 mice
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, amyotrophic lateral sclerosis; CMAP, compound muscle action potential; CMM, cutaneous maximus muscle; LTN, lateral thoracic nerve; NMJs, neuromuscular junctions; PBS, Phosphate-buffered saline; SOD1, superoxide dismutase 1; WT, wild type; YEP, Yellow
Exosomes and other extracellular vesicles in neural cells and neurodegenerative diseases
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; Aβ, amyloid β peptide; ALS, amyotrophic lateral sclerosis; APP, amyloid precursor protein; ARF6, ADP-ribosylation factor-6; AZ, active zone; CME, clathrin-mediated endocytosis; dMVB, multivesicular body involved in the degradation pathway; EE, early endos
Neuropathological characterization of spinal motor neuron degeneration processes induced by acute and chronic excitotoxic stimulus in vivo
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, amyotrophic lateral sclerosis; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazoleacetic acid; ccasp3, cleaved caspase 3; ChAT, choline acetyltransferase; GFAP, glial fibrillary acidic protein; MN, motor neuron; PB, phosphate buffer; PFA, paraformaldehyde;
Axonal degeneration, distal collateral branching and neuromuscular junction architecture alterations occur prior to symptom onset in the SOD1G93A mouse model of amyotrophic lateral sclerosis
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, amyotrophic lateral sclerosis; NMJ, neuromuscular junction; SOD1, superoxide dismutase 1 gene; SOD1G93A, transgenic mouse model of ALS; YFP, yellow fluorescent proteinNeuromuscular junction; SOD1G93A mouse; Amyotrophic lateral sclerosis; Distal 'dyin
Quercetin attenuates neuronal death against aluminum-induced neurodegeneration in the rat hippocampus
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AD, Alzheimer’s disease; ALS, Amyotrophic lateral sclerosis; CS, corpus striatum; cyt-c, cytochrome c; DCF, 2,7-dichlorofluorescein; EGTA, ethylene glycol tetraacetic acid; H&E, Hematoxylin and Eosin; HC, hippocampus; HEPES, 4-(2-hydroxyethyl)-1-piperazin
Oxysterol-binding protein ORP3 rescues the Amyotrophic Lateral Sclerosis-linked mutant VAPB phenotype
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, Amyotrophic Lateral Sclerosis; ER, endoplasmic reticulum; ERGIC, endoplasmic reticulum Golgi intermediate compartment; FFAT, two phenylalanines in an acidic tract; NE, Nuclear envelope; ORP, Oxysterol binding protein-related protein; PtdIns4KIII, Ptd
“Targeting astrocytes in CNS injury and disease: A translational research approach”
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AD, Alzheimer’s disease; AEG-1, astrocyte-elevated gene 1; ALS, amyotrophic lateral sclerosis; ApoE, apolipoprotein E; BBB, blood-brain barrier; BDNF, brain-derived neurotrophic factor; BLBP, brain lipid binding protein; BMP, bone morphogenetic protein; C
Secretory leukocyte protease inhibitor (SLPI), a multifunctional protein in the host defense response
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AHR, airway hyperresponsiveness; ALS, amyotrophic lateral sclerosis; CHIP, chromatin immunoprecipitation; CNS, central nervous system; COX, cyclooxygenase; HMG-1, high-mobility group 1; HSV, herpes simplex virus; ECM, extracellular matrix; IGFBP-3, insuli
ALS: A bucket of genes, environment, metabolism and unknown ingredients
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, amyotrophic lateral sclerosis; ALSFRS, ALS functional rating scale; BMAA, beta-N-methylamino-l-alanine; CNS, central nervous system; CNTF, ciliary neurotrophic factor; CSF, cerebrospinal fluid; CX3CR1, CX3C chemokine receptor 1; EAAT2, excitatory ami
Beneficial protective effect of pramipexole on light-induced retinal damage in mice
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; Age-related macular degeneration; Light-induced retinal damage; Apoptosis; Pramipexole; Antioxidant4-HNE, 4-hydroxynonenal; 8OHdG, 8-hydroxy-2-deoxyguanosine; ALS, amyotrophic lateral sclerosis; AMD, age-related macular degeneration; AREDS, age-related ey
Formation and characterisation of neuromuscular junctions between hiPSC derived motoneurons and myotubes
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; Ach, acetylcholine; AchR, acetylcholine receptor; ALS, amyotrophic lateral sclerosis; BDNF, brain derived neurotrophic factor; BT, bungarotoxin; EB, embryoid body; GDNF, glial derived neurotrophic factor; FGF, fibroblast growth factor; hiPSC, human induce
Sporadic lower motor neuron disease with a snake eyes appearance on the cervical anterior horns by MRI
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, amyotrophic lateral sclerosis; CMAP, compound muscle action potential; CSF, cerebrospinal fluid; DTR, deep tendon reflex; EMG, electromyogram; IVIG, intravenous immunoglobulin; LMND, lower motor neuron disease; MMN, multifocal motor neuropathy; MMT,
Human paraoxonase-1 (PON1): Gene structure and expression, promiscuous activities and multiple physiological roles
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; ALS, amyotrophic lateral sclerosis; CETP, cholesteryl-ester transfer protein; CHD, coronary heart disease; CPoxon, chlorpyrifos-oxon; DAMPs, damage associated molecular patterns; eNOS, endothelial nitric oxide synthase; GSH, reduced glutathione; GWS, Gulf
Comparative analysis of CsCu/ZnSOD defense role by molecular characterization: Gene expression-enzyme activity-protein level
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; Cu/ZnSOD, copper/zinc superoxide dismutase; ROS, reactive oxygen species; Cs, Channa striatus; FeSOD, iron SOD; NiSOD, nickel SOD; MnSOD, manganese SOD; EC SOD, extracellular Cu/ZnSOD; ALS, amyotrophic lateral sclerosis; EUS, epizootic ulcerative syndrome
Early activation of microglia and astrocytes in mouse models of spinocerebellar ataxia type 1
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; AD, Alzheimer’s disease; ALS, amyotrophic lateral sclerosis; ATXN1, ataxin-1; BG, Bergmann glia; DOX, doxycycline; GFAP, Glial Fibrilary Acidic Protein; HD, Parkinson’s disease; Iba1, ionized calcium-binding adapter molecule 1; IL6, Interleukin-6; SCA1, s
Curcumin binds to the pre-fibrillar aggregates of Cu/Zn superoxide dismutase (SOD1) and alters its amyloidogenic pathway resulting in reduced cytotoxicity
Keywords: ALS، اسکلروز جانبی جانبی آمیوتروفی; SOD1, Cu/Zn Superoxide Dismutase; ALS, Amyotrophic Lateral Sclerosis; fALS, familial amyotrpphic lateral sclerosis; sALS, sporadic amyotrophic lateral sclerosis, AAS, Atomic Absorption Spectroscopy; ATR-FTIR, Attenuated Total Reflectance Fourier Transform