Keywords: Amc، 7-amino-4-methylcoumarin; Colorado potato beetle; Peptidase; Cathepsin; Activity-based probe; Digestive system; Multienzyme networkABP, activity-based probe; Abz, 2-aminobenzoic acid; Ald, aldehyde; Amc, 7-amino-4-methylcoumarin; Bodipy, Bodipy TMR-X; BoFC, Bodipy-AAF-Cmk; BoRC, B
مقالات ISI Amc، 7-amino-4-methylcoumarin (ترجمه نشده)
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Cloning and characterization of a basic cysteine-like protease (cathepsin L1) expressed in the gut of larval Diaprepes abbreviatus L. (Coleoptera: Curculionidae)
Keywords: Amc، 7-amino-4-methylcoumarin; 3-D, three dimensional; AFC, 7-amino-4-trifluoromethylcoumarin; AMC, 7-amino-4-methylcoumarin; AeaTMOF, Aedes aegypti trypsin modulating oostatic factor; BME, β-mercaptoethanol; CA074, l-3-trans-(propylcarbamyl)oxirane-2-carbonyl)-l-isoleucyl-l-proline me
Desiccation tolerance of the resurrection plant Ramonda serbica is associated with dehydration-dependent changes in levels of proteolytic activities
Keywords: Amc، 7-amino-4-methylcoumarin; AMC, 7-amino-4-methylcoumarin; Bz, N-benzoyl; E-64, trans-epoxysuccinyl-l-leucylamido(4-guanidino)butane; PMSF, phenylmethylsulphonyl fluoride; pNA, p-nitroanilide; RWC, relative water content; Suc, N-succinyl; Z, N-α-benzyloxycarbonylAminopeptidase; Desi
Extracellular peptidases of imaginal discs of Drosophila melanogaster
Keywords: Amc، 7-amino-4-methylcoumarin; TFA, trifluoroacetic acid; RP-HPLC, reversed phase-high performance liquid chromatography; AMC, 7-amino-4-methylcoumarin; DPP IV, dipeptidyl peptidase IV; ACE, angiotensin-converting enzyme; Ance, Drosophila melanogaster angiotensin-converting enzyme; Ace
Design and synthesis of peptide-MCA substrates for a novel assay of histone methyltransferases and their inhibitors
Keywords: Amc، 7-amino-4-methylcoumarin; AcOH, acetic acid; Ac2O, acetic anhydride; AcOEt, ethyl acetate; AMC, 7-amino-4-methylcoumarin; DCM, dichloromethane; DCC, dicyclohexylcarbodiimide; DIEA, N,N-diisopropylethylamine; DMF, N,N-dimethylformamide; Fmoc, fluorenylmethyloxycarbonyl; HOBt·H2O, 1
Determining the impact of instrument variation and automated software algorithms on the TGT in hemophilia and normalized plasma
Keywords: Amc، 7-amino-4-methylcoumarin; TGT, thrombin generation test; CAT, calibrated automated thrombinography; AMC, 7-amino-4-methylcoumarin; NP, normalized plasma; HA, hemophilia A plasma; AUC, area under the curve; TPH, thrombin peak height; TTP, time to peak; LT, lagtime; α2MG, thrombin-α
A novel serine protease with caspase- and legumain-like activities from edible basidiomycete Flammulina velutipes
Keywords: Amc، 7-amino-4-methylcoumarin; Caspase-like activity; Edible basidiomycetes; Flammulina velutipes; Peptidase S41 family; Programmed cell death; Serine proteaseAc-YVAD-MCA, acetyl-Tyr-Val-Ala-Asp-4-methylcoumaryl-7-amide; PCD, programmed cell death; AMC, 7-amino-4-methylcoumarin; FvSerP
Analysis of Fasciola cathepsin L5 by S2 subsite substitutions and determination of the P1–P4 specificity reveals an unusual preference
Keywords: Amc، 7-amino-4-methylcoumarin; Cathepsin L; Protease; Fasciola hepatica; Liver fluke; S2 subsite; P2 substrate specificityaa69, amino acid residue 69; ACC, 7-amino-4-carbamoylmethylcoumarin; AMC, 7-amino-4-methylcoumarin; Boc, t-butyloxycarbonyl; Bz, N-benzoyl; E−64, transepoxysuccinyl
Recombinant expression and biochemical characterization of sugarcane legumain
Keywords: Amc، 7-amino-4-methylcoumarin; Vacuolar processing enzyme; Legumain; Sugarcane; Cystatin; Expression analysis; Sugarcane development; Phytohormone responseABA, abscisic acid; AMC, 7-amino-4-methylcoumarin; DAP, days after planting; E-64, trans-epoxysuccinyl-l-leucylamido(4-guanidino)bu
Cathepsins D and L reduce the toxicity of advanced glycation end products
Keywords: Amc، 7-amino-4-methylcoumarin; AGE, advanced glycation end product; AMC, 7-amino-4-methylcoumarin; BSA, bovine serum albumin; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; LAMP1, lysosomal-associated membrane protein 1; MOCA, (7-methoxycoumarin-4-yl) acetyl; MOCA-GKPILFFRLK (Dnp)-RN
Comparison of a fluorogenic anti-FXa assay with a central laboratory chromogenic anti-FXa assay for measuring LMWH activity in patient plasmas
Keywords: Amc، 7-amino-4-methylcoumarin; AMC, 7-amino-4-methylcoumarin; ACT, Activated clotting time; aPTT, Activated partial thromboplastin time; AT, Antithrombin; FXa, Factor Xa; Hepes, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; INR, International Normalized Ratio; LMWH, Low molecular
Comparison of the anticoagulant response of a novel fluorogenic anti-FXa assay with two commercial anti-FXa chromogenic assays
Keywords: Amc، 7-amino-4-methylcoumarin; AMC, 7-amino-4-methylcoumarin; ACT, Activated clotting time; aPTT, Activated partial thromboplastin time; AT, Antithrombin; AU, Arbitrary units; CV, Coefficient of variation; FXa, Factor Xa; Hepes, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; LMWH,
Quantification of unfractionated heparin in human plasma and whole blood by means of novel fluorogenic anti-FXa assays
Keywords: Amc، 7-amino-4-methylcoumarin; UFH, unfractionated heparin; FXa, factor Xa; APTT, activated partial thromboplastin time; ACT, activated clotting time; AMC, 7-amino-4-methylcoumarin; SN-7, Mes-D-LGR-ANSN (C2H5)2 fluorogenic substrate; ANSN, 6-amino-1-naphthalene-sulfonamide; DCU, Dublin
Development and characterisation of an assay for furin activity
Keywords: Amc، 7-amino-4-methylcoumarin; PC, proprotein convertase; TGF-β, transforming growth factor beta; MD, minimum detection limit; AMC, 7-amino-4-methylcoumarin; CV, coefficient of variation; HRP, horseradish peroxidaseFurin; Assay; Transforming growth factor beta
Anthracene-based inhibitors of dengue virus NS2B–NS3 protease
Keywords: Amc، 7-amino-4-methylcoumarin; DENV, dengue virus; DEN2V, dengue 2 virus; NS, nonstructural; NS2B–NS3pro, NS3 protease domain with NS2B cofactor; DHF, dengue hemorrhagic fever; DSS, dengue shock syndrome; GKR, glycine–lysine–arginine; AMC, 7-amino-4-methylcoumarin; SAR, structure activ
The accumulation of neurotoxic proteins, induced by proteasome inhibition, is reverted by trehalose, an enhancer of autophagy, in human neuroblastoma cells
Keywords: Amc، 7-amino-4-methylcoumarin; AD, Alzheimer's disease; ALP, autophagy-lysosomal pathway; AMC, 7-amino-4-methylcoumarin; BrdU, bromodeoxyuridine; ERK, extracellular-signal-regulated kinase; GSK-3, glycogen synthase kinase 3; GSH, glutathione; HSP, heat shock proteins; HD, Huntington's
Biochemical characterization of Plasmodium falciparum dipeptidyl aminopeptidase 1
Keywords: Amc، 7-amino-4-methylcoumarin; ACC, 7-amino-4-carbamoylcoumarin; AEBSF, 4-(2-aminoethyl)benzenesulfonyl fluoride; AMC, 7-amino-4-methylcoumarin; DPAP, dipeptidyl aminopeptidase; EDTA, ethylenediaminetetraacetic acid; IMAC, immobilized metal affinity chromatography; MBP, maltose binding
Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization
Keywords: Amc، 7-amino-4-methylcoumarin; AhR, aryl hydrocarbon receptor; AO, acridine orange; Ac-DEVD-AMC, acetyl-Asp-Glu-Val-Asp-7-amino-4-methylcoumarin; AMC, 7-amino-4-methylcoumarin; C11, C11-BODIPY581/591 or 4,4-difluoro-5-(4-phenyl-1,3,butadienyl)-4-bora-3a,4a-diaza-s-indacene-3-undecanoic
Long bone osteoclasts display an augmented osteoclast phenotype compared to calvarial osteoclasts
Keywords: Amc، 7-amino-4-methylcoumarin; TRAP, tartrate-resistant acid phosphatase; FPLC, fast protein liquid chromatography; AMC, 7-amino-4-methylcoumarin; CtsK, cathepsin KTartrate-resistant acid phosphatase; Purple acid phosphatase; Acp 5; Cysteine proteinase; Osteoclast
Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function: Possible links between diabetes and atherosclerosis
Keywords: Amc، 7-amino-4-methylcoumarin; AMC, 7-amino-4-methylcoumarin; BSA, bovine serum albumin; DTT, dithiothreitol; GA, glycolaldehyde; GO, glyoxal; MGO, methylglyoxal; PBS, phosphate-buffered salineDiabetes-associated atherosclerosis; Proteasome; Glycated proteins; Advanced glycation end pr
The cell-penetrating peptide octa-arginine is a potent inhibitor of proteasome activities
Keywords: Amc، 7-amino-4-methylcoumarin; Cell-penetrating peptides; Octa-arginine; Proteasome; Inhibitor; Ubiquitin-conjugated proteins; HeLa cellsArg, arginine; Bz-VGR, benzoyl-Val-Gly-Arg; CPP, cell-penetrating peptide; AMC, 7-amino-4-methylcoumarin; Suc-LLVY, succinyl-Leu-Leu-Val-Tyr; Z-LLE,
Characterization and cloning of cysteine protease that is induced in green leaves of barley
Keywords: Amc، 7-amino-4-methylcoumarin; AMC, 7-amino-4-methylcoumarin; HvCP, Horedeum vulgare cysteine protease; PCR, polymerase chain reaction; Suc-LLVY-MCA, N-succinyl-Leu-Leu-Val-Tyr-4-methyl-coumaryl-7-amideBarley; Cysteine protease; Cysteine protease inhibitor complex; Green leaves
Activation of oligopeptidase B from Streptomyces griseus by thiol-reacting reagents is independent of the single reactive cysteine residue
Keywords: Amc، 7-amino-4-methylcoumarin; Boc, t-butoxycarbonyl; Z, benzyloxycarbonyl; Pyr, l-pyroglutamyl; AMC, 7-amino-4-methylcoumarin; Tos, Tosyl; Cit, citrulline; Abz, 2-aminobenzoyl; pNA, p-nitroanilide; SGR-OpdB, Streptomyces griseus oligopeptidase B; DTT, dithiothreitol; GSH, reduced glut
Pro-oxidant and proapoptotic effects of cholesterol oxidation products on human colonic epithelial cells: A potential mechanism of inflammatory bowel disease progression
Keywords: Amc، 7-amino-4-methylcoumarin; Ac-DEVD-AMC, acetyl-Asp-Glu-Val-Asp-7-amino-4-methylcoumarin; ALP, alkaline phosphatase; AMC, 7-amino-4-methylcoumarin; DAPI, 4,4-diamidino-2-phenylindole dihydrochloride; DCF, 2′,7′-dichlorofluorescein; DCFH-DA, 2′,7′-dichlorofluorescin diacetate; DMEM,
Polyphyllin D induces mitochondrial fragmentation and acts directly on the mitochondria to induce apoptosis in drug-resistant HepG2 cells
Keywords: Amc، 7-amino-4-methylcoumarin; AIF, apoptosis-inducing factor; AMC, 7-amino-4-methylcoumarin; Dox, doxorubicin; Grp, glucose regulatory protein; JC-1, 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethyl-benzimidazolcarbocyanine iodide; MDR, multi-drug resistance; PARP, poly (ADP-ribose) polymer
One-chip sensing device (biomedical photonic LSI) enabled to assess hippocampal steep and gradual up-regulated proteolytic activities
Keywords: Amc، 7-amino-4-methylcoumarin; BpLSI, biomedical photonic LSI; LTP, long-term potentiation; NMDA, N-methyl-d-aspartate; E-LTP, early phase of LTP; CMOS, complementary metal-oxide semiconductor; LED, light-emitting diode; AMC, 7-amino-4-methylcoumarin; fEPSP, field excitatory post-synap
Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus
Keywords: Amc، 7-amino-4-methylcoumarin; SARS, severe acute respiratory syndrome; CoV, coronavirus; PLpro, papain-like proteinase 2; 3CLpro, 3-chymotrypsin-like protease; DUB, deubiquitination enzyme; AMC, 7-amino-4-methylcoumarin; FRET, fluorescence resonance energy transfer; 6MP, 6-mercaptopur
Implication of caspases and subcellular compartments in tert-butylhydroperoxide induced apoptosis
Keywords: Amc، 7-amino-4-methylcoumarin; AMC, 7-amino-4-methylcoumarin; AFC, 7-amino-4-trifluoromethylcoumarin; AIF, Apoptosis-inducing factor; DTT, Dithiothreitol; ER, Endoplasmic reticulum; FBS, Fetal bovine serum; IMS, Inter-membrane space; MEM, Minimal essential medium; PTP, Mitochondrial pe
Seprase: An overview of an important matrix serine protease
Keywords: Amc، 7-amino-4-methylcoumarin; AEBSF, 4-(2-aminoethyl)-benzenesulfonyl fluoride; AFC, 7-amino-4-trifluoromethylcoumarin; AMC, 7-amino-4-methylcoumarin; APSF, 4-amidino phenylsulfonyl fluoride; DABCYL, 4-(4-dimethylaminophenylazo)benzoyl; DFP, Diisopropyl fluorophosphates; DPPIV, Dipept
Solvent and thermal stability, and pH kinetics, of proline-specific dipeptidyl peptidase IV-like enzyme from bovine serum
Keywords: Amc، 7-amino-4-methylcoumarin; ACN, acetonitrile; ADAbp, adenosine deaminase binding protein; AMC, 7-amino-4-methylcoumarin; BCA, bicinchoninic acid; CD26, cluster of differentiation molecule 26; CHES, 2-(cyclohexylamino)ethanesulfonic acid; DMF, dimethylformamide; DMSO, dimethylsulfox
Metacaspase 2 of Trypanosoma brucei is a calcium-dependent cysteine peptidase active without processing
Keywords: Amc، 7-amino-4-methylcoumarin; MCA, metacaspase; PCD, programmed cell death; AMC, 7-amino-4-methylcoumarin; EF-Tu, elongation factor Tu; GST, glutathione S-transferase; TLCK, tosyl-lysyl-chloromethylketoneCaspase; Metacaspase; Cysteine protease; Calcium
Caspase-7 mediated cleavage of proteasome subunits during apoptosis
Keywords: Amc، 7-amino-4-methylcoumarin; AMC, 7-amino-4-methylcoumarin; z-DEVD-fmk, carbobenzoxy-Asp-Glu-Val-Asp-fluoromethylketone; ac-DEVD-pNA, N-acetyl-Asp-Glu-Val-Asp-p-nitroanilide; NDGA, nordihydroguaiaretic acidApoptosis; Caspase-7; 2-DE; Proteasome; Ubiquitination
Cloning and characterization of cathepsin L-like peptidases of Echinococcus multilocularis metacestodes
Keywords: Amc، 7-amino-4-methylcoumarin; AMC, 7-amino-4-methylcoumarin; CHAPS, 3-[(3-cholamidopropyl)dimethylammonia]-1-propanesulfonic acid; DTT, dithiothreitol; ES, excretory/secretory; E-64, trans-epoxysuccinyl-l-leucylamido(4-guanidino)butane; MCA, 4-methylcoumarin-7-amide; NTA, nitrilotriac
Sperm proteasomes are responsible for the acrosome reaction and sperm penetration of the vitelline envelope during fertilization of the sea urchin Pseudocentrotus depressus
Keywords: Amc، 7-amino-4-methylcoumarin; AMC, 7-amino-4-methylcoumarin; ASW, artificial seawater (460 mM NaCl, 10 mM CaCl2, 50 mM MgCl2, 10 mM KCl, 50 mM Tris/HCl (pH 8.0)); Boc, t-butyloxycarbonyl; BSA, bovine serum albumin; DMSO, dimethylsulfoxide; DTT, dithiothreitol; MCA, 4-methylcoumaryl-7-
Relationship between Propeptide pH Unfolding and Inhibitory Ability during ProDer p 1 Activation Mechanism
Keywords: Amc، 7-amino-4-methylcoumarin; AMC, 7-amino-4-methylcoumarin; ANS, 8-anilino-1-naphthalenesulfonic acid; Boc, N-t-butoxy-carbonyl; EDTA, ethylenediaminetetraacetic acid; PBS, phosphate buffered saline; ProDer p 1, protease Der p 1 zymogen; rDer p 1, recombinant Der p 1; SPR, surface pl
Interactive effects of fumonisin B1 and α-zearalenol on proliferation and cytokine expression in Jurkat T cells
Keywords: Amc، 7-amino-4-methylcoumarin; FB1, fumonisin B1; α-ZEA, α-zearalenol; IL-2, interleukin-2; IFN γ, interferon γ; FBS, foetal bovine serum; PCR, polymerase chain reaction; cpm, counts per minute; PMA, phorbol 12-myristate 13-acetate; AMC, 7-amino-4-methylcoumarin; Ac-DEVD-AMC, acetyl As
Kinetics, inhibition and oligomerization of Epstein-Barr virus protease
Keywords: Amc، 7-amino-4-methylcoumarin; Ac, acetyl; Aca, 6-aminocaproic acid; AMC, 7-amino-4-methylcoumarin; Boc, tert-butyloxycarbonyl; DLS, dynamic light scattering; DMF, dimethylformamide; DMSO, dimethylsulfoxide; EBV, Epstein-Barr virus; Fmoc, N-(9-fluorenyl)methoxycarbonyl; HBTU, N-[(1H-be
SIRT1 stimulation by polyphenols is affected by their stability and metabolism
Keywords: Amc، 7-amino-4-methylcoumarin; AMC, 7-amino-4-methylcoumarin; EC, (−)-epicatechin; ECg, (−)-epicatechin gallate; EGC, (−)-epigallocatechin; EGCg, (−)-epigallocatechin gallate; NAD, nicotinamide adenine dinucleotide; sir2, silent information regulator 2; SIRT1, silent information regula
c-Jun N-terminal kinase upregulation as a key event in the proapoptotic interaction between transforming growth factor-β1 and 4-hydroxynonenal in colon mucosa
Keywords: Amc، 7-amino-4-methylcoumarin; Ac-DEVD-AMC, N-acetyl-Asp-Glu-Val-Asp-AMC; AMC, 7-amino-4-methylcoumarin; AP-1, activator protein-1; Co-Smad4, common-partner Smad4; DMEM, Dulbecco's modified Eagle's medium; ERK, extracellular-signal-related kinases; FBS, fetal bovine serum; HNE, 4-hydro
Catalytic residues and substrate specificity of scytalidoglutamic peptidase, the first member of the eqolisin in family (G1) of peptidases
Keywords: Amc، 7-amino-4-methylcoumarin; FRETS, fluorescence resonance energy transfer substrate; MCA, peptidyl-4-methyl-coumaryl-7-amides; AMC, 7-amino-4-methylcoumarin; Bz, benzoyl; MeNHBz, 2-(N-methylamino)benzoyl; Dap, D-2,3-diamino propionic acid; Dnp, 2,4-dinitrophenyl; LC–MS, liquid chrom
Identification of the reactive cysteine residues in oligopeptidase B from Trypanosoma brucei
Keywords: Amc، 7-amino-4-methylcoumarin; AMC, 7-amino-4-methylcoumarin; Cbz, carbobenzyloxy; DTT, dithiothreitol; GSH, reduced glutathione; IAA, iodoacetic acid; IAN, iodoacetamide; kass, apparent second-order inhibition rate constant; NEM, N-ethylmaleimide; OpdB, oligopeptidase B; pCMB, para-ch