The role of Asn-212 in the catalytic mechanism of human endonuclease APE1: Stopped-flow kinetic study of incision activity on a natural AP site and a tetrahydrofuran analogue
Keywords: APE1, AP endonuclease1; WT, wild type; BER, base excision repair; AP, abasic site; F, 2-hydroxymethyl-3-hydroxy-tetrahydrofuran; 2-aPu, 2-aminopurine; ODN, oligodeoxyribonucleotide; MD, molecular dynamicsBase excision repair; APE1; Abasic site; Stopped-fl