Distortion of frontal bones results from cell apoptosis by the mechanical force from the up-migrating eye during metamorphosis in Paralichthys olivaceus
Keywords: Flatfish; Frontal bones; Cell apoptosis; Mechanical force; Eye migration; MetamorphosisAEC, 3-amino-9-ethyl carbazole; Apaf-1, apoptosis protease activating factor-1; BAX, bcl-2 associated X protein; BMP-2, bone morphogenetic protein 2; BrdU, 5′-bromodeox