Self-pMHCII complexes are variably expressed in the thymus and periphery independent of mRNA expression but dependent on the activation state of the APCs
Keywords: APL، لیگاند پپتید تغییر یافته است; APL, altered peptide ligand; cTEC, cortical thymic epithelial cell; mTEC, medullary thymic epithelial cell; PTM, post translational modificationCD4+ T cell; Self-pMHCII; Positive selection; Negative selection