γ-secretase processing of APLP1 leads to the production of a p3-like peptide that does not aggregate and is not toxic to neurons
Keywords: APLP, Amyloid precursor-like protein; ALP-1, APLP1-derived peptide; Aβ, amyloid β-protein; CTFs, carboxy-terminal fragments; CM, conditioned mediaAlzheimer's disease; Amyloid precursor-like protein-1; Aggregation; Fibrillogenesis; Neurotoxicity; Amyloid β