
Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells
Keywords: AGEs, advanced glycation-end products; ARE, anti-oxidant response element; BSA, bovine serum albumin; DN, diabetic nephropathy; ECM, extracellular matrix; EMSA, electrophoretic mobility shift assay; FN, fibronectin; GMCs, glomerular mesangial cells; HG, h