
Role of cytochrome P450-mediated metabolism and identification of novel thiol-conjugated metabolites in mice with phenytoin-induced liver injury
Keywords: ABT; 1-aminobenzotriazole; ALT; alanine aminotransferase; BSO; l-buthionine-(S,R)-sulfoximine; Cys; cysteine; DPH; phenytoin; γ-GCS; γ-glutamilcysteine synthetase; 4â²-HPPH; 5-(4â²-hydroxyphenyl)-5-phenylhydantoin; MDZ; midazolam; NAC; N-acetylcystein