Keywords: آزبست; NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; FC; free cholesterol; VLDL; very low density lipoprotein; LDL; low density lipoprotein; mTOR; mechanistic target of rapamycin signaling; AMPK; AMP-activated protein kinase; TG; t
مقالات ISI آزبست (ترجمه نشده)
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Keywords: آزبست; ABC; ATP-binding cassette; ASBT; apical sodium-dependent bile acid transporter; Bamet-UD2; cisplatin-ursodeoxycholic acid derivative; CCA; cholangiocarcinoma; DHMEQ; dehydroxymethyl epoxyquinomicin; EGFR; epidermal growth factor receptor; 5-FU; 5-fluorour
Keywords: آزبست; ABC; transporter; ATP; binding cassette transporter; AR; androgen receptor; ASBT; apical sodium-dependent bile acid transporter; BBB; blood-brain barrier; BCRP; breast cancer resistance protein; BT; Bblood-testis barrier; CS; cholesterol sulfate; DHEA; de
Keywords: آزبست; α-CGRP; alpha-calcitonin gene related peptide; Ang; angiopoietin; AE2; anion exchanger 2; ADP; adenosine diphosphate; ADPKD; autosomal dominant polycystic kidney disease; ATP; adenosine triphosphate; ASBT; sodium-dependent bile acid transporter; AQP; aqu
Keywords: آزبست; ASBT; apical sodium-dependent bile acid transporter; BMI; body mass index; CA; cholic acid; CA-D4; cholic acidâ2,2,4,4âD4; CARB; Carbohydrate and Related Biomarkers; CDCA; chenodeoxycholic acid; CRP; C-reactive protein; CV; coefficient of variation; D
Keywords: آزبست; ASBT; apical sodium-dependent bile acid transporter; ASDs; amorphous solid dispersions; BACS; bile acid-CoA synthase; BAT; bile acid-amino acid transferase; BCS; biopharmaceutics classification system; BSH; bile salt hydrolase; C4; 7α-hydroxy-4-cholesten
Keywords: آزبست; Asbt; apical sodium-dependent bile acids transporter; BAs; bile acids; Bsep; bile salt export pump; β-MCA; β-muricholic acid; CA; cholic acid; CDCA; chenodeoxycholic acid; Cyp3a11; cytochrome P450 3a11 (human CYP3A4); Cyp7a1; cholesterol 7α-hydroxylase
Keywords: آزبست; Bile Acids; FXR; TGR5; Meta-Inflammation; apo; apolipoprotein; ASBT; apical sodiumâdependent bile acid transporter; BA; bile acid; BAS; bile acid sequestrant; BAT; brown adipose tissue; BSH; bile salt hydrolase; CA; cholic acid; CCK; cholecystokinin; CD
Keywords: آزبست; ABCB; ATP-binding cassette sub-family B; Apo; apolipoprotein; ASBT; apical sodium dependent bile acid transporter; BDL; bile duct ligation; BSEP; bile salt export pump; CA; cholic acid; CDCA; chenodeoxycholic acid; C/EBP; CCAAT-enhancer-binding protein; C
Keywords: آزبست; ASBT; apical sodium dependent transporter; AKT; protein kinase B; BSEP; bile salt export protein (ABCB11); CA; cholic acid; CCA; cholangiocarcinoma; CDCA; chenodeoxycholic acid; CYP7A1; cholesterol 7α-hydroxylase; CYP7B1; oxysterol 7α-hydroxylase; CYP27
Keywords: آزبست; GC; glucocorticoid; BA; bile acid; GR; glucocorticoid receptor; FXR; farnesoid X receptor; SHP; short heterodimer partner; Asbt; Apical sodium-dependent bile acid transporter; CA; cholic acid; DCA; deoxycholic acid; α-MCA; α-muricholic acid; β-MCA; β-
Keywords: آزبست; AL; ad libitum; Asbt; apical sodium-dependent bile acid transporter; BA; bile acid; BAL; bile acid-CoA ligase; BAT; bile acid-CoA: amino acid N-acyltransferase; Bsep; bile salt export pump; CA; cholic acid; CDCA; chenodeoxycholic acid; CR; calorie restric
The ileum-liver Farnesoid X Receptor signaling axis mediates the compensatory mechanism of 17α-ethynylestradiol-induced cholestasis via increasing hepatic biosynthesis of chenodeoxycholic acids in rats
Keywords: آزبست; Asbt; apical sodium-dependent bile acids transporter; ALP; alkaline phosphatase; ALT; alanine transaminase; AST; aspartate transaminase; BAs; bile acids; Bsep/BSEP; bile salt export pump; β-MCA; β-muricholic acid; CA; cholic acid; CDCA; chenodeoxycholic
Intestinal Farnesoid X Receptor Activation by Pharmacologic Inhibition of the Organic Solute Transporter α-β
Keywords: آزبست; Fluorescence Resonance Energy Transfer (FRET); FXR; OSTα-OSTβ; Bile Acids; ASBT; apical sodium-dependent bile acid transporter; BAS; bile acid sensor; FACS; fluorescence-activated cell sorting; FDA; Food and Drug Administration; FGF15/19; fibroblast gro
ApoE is a major determinant of hepatic bile acid homeostasis in mice
Keywords: آزبست; ApoE; apolipoprotein E; BA; bile acid; HCHF; high-cholesterol/high-fat liver; Lrh; receptor homolog-1; Srebp1; sterol regulatory element-binding protein; Shp; small heterodimer partner; MCA; muricholic acid; CDCA; chenodeoxycholic acid; MRM; multiple reac
Genetic determinants of cholangiopathies: Molecular and systems genetics
Keywords: آزبست; AP; alkaline phosphatase; ASBT; apical sodium bile acid transporter; BRIC; benign recurrent intrahepatic cholestasis; CC; collaborative cross; DILI; drug-induced liver injury; É£-GT; É£-glutamyl transpeptidase; GRP; genetic reference populations; GWAS; ge
Human and rat precision-cut intestinal slices as ex vivo models to study bile acid uptake by the apical sodium-dependent bile acid transporter
Keywords: آزبست; ASBT; apical sodium-dependent bile acid transporter; DMSO; dimethyl sulfoxide; NTCP; Na+-taurocholate cotransporting polypeptide; OATP; organic anion transporting polypeptide; PBS; phosphate buffered saline; PCIS; precision-cut intestinal slices; PPPD; pa
Transhepatic bile acid kinetics in pigs and humans
Keywords: آزبست; Bile acids; TGR5; Porcine; Postprandial; Portal concentrations; BAs; bile acids; ASBT; apical sodium-dependent bile acid transporter; OST; organic solute transporter; NTCP; taurocholate cotransporting polypeptide; OATP; organic anion transporting polypept
Activation of PPARα decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion
Keywords: آزبست; Biliary excretion; PPARα; Bile acids; Gender difference; 1oBAs; Primary bile acids; 2oBAs; secondary bile acids; 12-OH; 12-hydroxylated bile acid; Asbt; apical sodium-dependent bile acid transporter; BA; bile acid; Baat; bile acid CoA:amino acid N-acyltr
Intake of stigmasterol and β-sitosterol alters lipid metabolism and alleviates NAFLD in mice fed a high-fat western-style diet
Keywords: آزبست; ABCA1; ATP binding cassette transporter A1; ABCG5; ATP binding cassette transporter 5; ALT; alanine aminotransferase; ASBT; ileal apical sodium-dependent bile acid transporter; BA; bile acid(s); BSEP; bile salt export pump; CD36; Cluster of Differentiatio
Aryl hydrocarbon receptor (AhR) mediated short-term effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on bile acid homeostasis in mice
Keywords: آزبست; Aryl hydrocarbon receptor; TCDD; Bile acids; Biliary excretion; Taurodeoxycholic acid; Cyp8b1; 1°BAs; Primary bile acids; 2°BAs; Secondary bile acids; 6-OH; 6-hydroxylated (6-OH); 12-OH; 12α-hydroxylated; Abc; ATP-binding cassette; AhR; Aryl hydrocarbo
Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR
Keywords: آزبست; Natural products; Nuclear receptors; Liver X receptor; Farnesoid X receptor; Retinoid X receptor; Metabolic syndrome; Precision medicine; 6-ECDCA; 6α-ethyl-chenodeoxycholic acid (obeticholic acid); AA; arachidonic acid; ABC; ATP-binding cassette transpor
An important intestinal transporter that regulates the enterohepatic circulation of bile acids and cholesterol homeostasis: The apical sodium-dependent bile acid transporter (SLC10A2/ASBT)
Keywords: آزبست; ASBT; apical sodium-dependent bile acid transporter; BAs; bile acids; PEPT1; peptide transporter 1; OCT1; organic cation transporter 1; OST alpha/beta; organic solute transporter alpha/beta; NTCP; Na+/taurocholate-cotransporting polypeptide; DDIs; drug-
Irinotecan-induced bile acid malabsorption is associated with down-regulation of ileal Asbt (Slc10a2) in mice
Keywords: آزبست; CPT-11; irinotecan; TBAs; total bile acids; BAM; bile acid malabsorption; ASBT; apical Na+-dependent bile salt transporter; EHC; enterohepatic circulation; IS; internal standard; NDCA; nor-desoxycholic acid; d4-CDCA; d4-chenodeoxycholic; CA; cholic acid;
Anti-hyperlipidemic effects of Rhizoma Coptidis alkaloids are achieved through modulation of the enterohepatic circulation of bile acids and cross-talk between the gut microbiota and the liver
Keywords: آزبست; ASBT; apical sodium-dependent bile salt transporter; BSEP; bile salt export pump; COX2; cyclooxygenase 2; CYP7A1; cholesterol 7α-hydroxylase; FXR; farnesoid X receptor; HFHC; high fat and high cholesterol; HMGCR; 3-hydroxy-3-methyl glutaryl coenzyme A re
The Farnesoid X Receptor: Good for BAD
Keywords: آزبست; Bile Acid Diarrhea; Enterohepatic Circulation; FGF-19; Chloride Secretion; Epithelium; ASBT; apical sodium-linked bile acid transporter; BAD; bile acid diarrhea; C4; 7α-hydroxy-4-cholesten-3-one; CA; cholic acid; CDCA; chenodeoxycholic acid; DCA; deoxych
Characterizing drug-metabolizing enzymes and transporters that are bona fide CAR-target genes in mouse intestine
Keywords: آزبست; Aldh; aldehyde dehydrogenase; Asbt; solute carrier family 10, member 2 (apical sodium/bile acid cotransporter); CAR; constitutive androstane receptor; cDNA; complementary DNA; CITCO; 6-(4-chlorophenyl)imidazo [2,1-b](1,3)thiazole-5-carbaldehyde O-(3,4-dic
Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes
Keywords: آزبست; ABC; ATP-binding cassette transporter; AGPAT2; 1-acylglycerol-3-phosphate O-acyltransferase; AhR; arylhydrocarbon receptor; AKR1C1; aldo-keto reductase 1C1; APO; apolipoprotein; ASBT; apical sodium dependent bile acid transporter; BAs; bile acids; BSEP; b
Restoration of enterohepatic bile acid pathways in pregnant mice following short term activation of Fxr by GW4064
Keywords: آزبست; Asbt; apical sodium-dependent bile acid transporter; Baat; bile acid CoA:amino acid N-acetyltransferase; Bal; bile acid CoA ligase; Bsep; bile salt export pump; Cyp; cytochrome P450; Fgf; fibroblast growth factor; Fxr; farnesoid X receptor; I-babp; ileal
HDL functionality in reverse cholesterol transport - Challenges in translating data emerging from mouse models to human disease
Keywords: آزبست; ABC; ATP-binding cassette transporter; Apo; apolipoprotein; apobec1; apoB mRNA editing enzyme; ASBT; apical sodium-dependent bile acid transporter; BA; bile acids; BAT; bile acid CoA:amino acid N-acyltransferase; BSEP; bile salt export pump; CEC; choleste
Research ArticleGut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4
Keywords: آزبست; BA; bile acid; Asbt; apical sodium-dependent bile acid transporter; KO; knock-out; iKO; intestinal-specific knock-out; WT; wildtype; CA; cholic acid; CDCA; chenodeoxycholic acid; MCA; muricholic acid; UDCA; urodeoxycholic acid; Gut microbiota; Intestinal
ReviewNew paradigms in the treatment of hepatic cholestasis: From UDCA to FXR, PXR and beyond
Keywords: آزبست; AE2; anion exchanger 2; ASBT; apical sodium bile salt transporter; BA; bile acid; CA; cholic acid; CDCA; chenodeoxycholic acid; CFALD; cystic fibrosis-associated liver disease; CFTR; cystic fibrosis transmembrane conductance regulator; DCA; deoxycholic ac
Vitamin D Receptor Activation Down-regulates the Small Heterodimer Partner and Increases CYP7A1 to Lower Cholesterol
Keywords: آزبست; Liver; Bile Acid; Farnesoid X Receptor; Transcriptional Regulation; Asbt; rodent apical sodium dependent bile acid transporter; CDCA; chenodeoxycholic acid; ChIP; chromatin immunoprecipitation; Cyp7a1/CYP7A1; rodent/human cholesterol 7α-hydroxylase; 1,25
Cholestatic effect of epigallocatechin gallate in rats is mediated via decreased expression of Mrp2
Keywords: آزبست; Epigallocatechin gallate; Bile formation; Cholestasis; Bile acids; Asbt; apical sodium-dependent bile salt transporter; ALT; alanine transaminase; AST; aspartate transaminase; Bsep; bile salt exporting pump; CDCA; chenodeoxycholic acid; Cyp7a1; cholestero
Ileal apical sodium-dependent bile acid transporter protein levels are down-regulated through ubiquitin-dependent protein degradation induced by bile acids
Keywords: آزبست; ASBT; Ubiquitination; Bile acid; Enterobacteria; Antibiotics; MG132;
Disruption of Stard10 gene alters the PPARα-mediated bile acid homeostasis
Keywords: آزبست; StAR; steroidogenic acute regulatory protein; START; StAR-related lipid transfer; STARD10/Stard10; START domain containing 10; WT; wild type; ASBT/Asbt; apical sodium dependent bile acid transporter; STARD2/Stard2; START domain containing 2; CA; cholic ac
The solute carrier family 10 (SLC10): Beyond bile acid transport
Keywords: آزبست; SLC10; Bile acid; ASBT; NTCP; SOAT; TGR5;
Methods for Diagnosis of Bile Acid Malabsorption in Clinical Practice
Keywords: آزبست; SeHCAT; C4; Glycocholate; Fecal; Diarrhea; ASBT; Na+-dependent bile salt transporter; BA; bile acid; BAM; bile acid malabsorption; CA; cholic acid; CDCA; chenodeoxycholic acid; CYP7A1; cholesterol 7α hydroxylase; C4; 7 α-hydroxy-4-cholesten-3-one; DCA;
Research ArticleMouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism
Keywords: آزبست; BA; bile acid(s); Asbt; apical sodium-dependent bile acid transporter; Ost; organic solute transporter; FXR; farnesoid X receptor; FGF15; fibroblast growth factor 15; Cyp7a1; cholesterol 7α-hydroxylase; FGFR4; fibroblast growth factor receptor 4; CA; cho
Research ArticleEffect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health
Keywords: آزبست; UDCA; ursodeoxycholic acid; PBC; primary biliary cirrhosis; ASBT; apical sodium-dependent bile acid transporter; FXR; farnesoid X receptor; PXR; pregnane X receptor; VDR; vitamin D receptor; CA; cholic acid; CDCA; chenodeoxycholic acid; DCA; deoxycholic a
Identification of Novel Nonsteroidal Compounds as Substrates or Inhibitors of hASBT
Keywords: آزبست; nonsteroidal; substrate; inhibitor; ASBT; prodrug; bile acid;
MALDI-TOF mass spectrometry screening of cholelithiasis risk markers in the gene of HNF1alpha
Keywords: آزبست; Gallstone; HNF1alpha; ASBT; Polymorphism; SNP; Male
Intestinal Epithelial Toll-Like Receptor 4 Regulates Goblet Cell Development and Is Required for Necrotizing Enterocolitis in Mice
Keywords: آزبست; Development; Mouse Model; Microbiota; Pediatric Gastrointestinal Disorder; ASBT; apical ileal sodium-dependent bile acid transporter; DAPI; 4â²,6-diamidino-2-phenylindole; DBZ; dibenzapine; GFP; green fluorescent protein; IL; interleukin; LPS; lipopolysa
Defects in Gallbladder Emptying and Bile Acid Homeostasis in Mice With Cystic Fibrosis Transmembrane Conductance Regulator Deficiencies
Keywords: آزبست; Enterohepatic Circulation; Cholehepatic Shunt; Bicarbonate Secretion; Bile Acid Transporters; Asbt; apical sodium-dependent bile salt transporter; BA; bile acid; cAMP; adenosine 3â²,5â²-cyclic monophosphate; Cck; cholecystokinin; CF; cystic fibrosis; CF
Getting the mOST from OST: Role of organic solute transporter, OSTα-OSTβ, in bile acid and steroid metabolism
Keywords: آزبست; ABC; ATP-binding cassette; ASBT; apical sodium-dependent bile acid transporter; DHEA; dehydroepiandrosterone; DHEAS; dehydroepiandrosterone-3-sulfate; ER; endoplasmic reticulum; Endo H; endoglycosidase H; FGF; fibroblast growth factor; FGFR; fibroblast gr
A New Mechanism for Bile Acid Diarrhea: Defective Feedback Inhibition of Bile Acid Biosynthesis
Keywords: آزبست; ASBT; apical sodium-dependent bile acid transporter; BA; bile acid; BAM; bile acid malabsorption; C4; 7α-hydroxy-4-cholesten-3-one; CYP7A1; cholesterol 7α hydroxylase; ELISA; enzyme-linked immunosorbent assay; FGFR4; fibroblast growth receptor 4; FGF15;
Altered bile composition after liver transplantation is associated with the development of nonanastomotic biliary strictures
Keywords: آزبست; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ASBT; apical sodium-dependent bile acid transporter; AUC; area under the curve; BS; bile salts; BSEP; bile salt export pump; CH; cholesterol; FI; fold induction; γ
GATA4 mediates gene repression in the mature mouse small intestine through interactions with friend of GATA (FOG) cofactors
Keywords: آزبست; GATA4; Friend of GATA; FOG; Intestinal differentiation; Apical sodium-dependent bile acid transporter; ASBT
Intestinal bile salt absorption in Atp8b1 deficient mice
Keywords: آزبست; Atp8b1; Bile salts; Asbt; Ussing chamber; Intestine
Inhibition of the intestinal absorption of bile acids using cationic derivatives: Mechanism and repercussions
Keywords: آزبست; ASBT; Enterohepatic circulation; Ileum; Intestine; Liver; Polyamine; TransportASBT, apical sodium-dependent bile acid transporter; BAPA, bile acid-polyamine derivative; BSEP, bile salt export pump; CDCA, chenodeoxycholic acid; GC, glycocholic acid; NTCP,