دانلود مقالات ISI درباره ATR، ATM و Rad3 مرتبط است + ترجمه فارسی

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Synthetic lethal approaches for assessing combinatorial efficacy of chemotherapeutic drugs

Keywords: ATR، ATM و Rad3 مرتبط است; Synthetic lethality; Epigenetics; High-throughput screening; Genomics; Signaling networksATM, ataxia telangiectasia, mutated; ATR, ATM and Rad3-related; ATRIP, ATR-interacting protein; BAF, Brg1-associated factor; BER, base excision repair; BRCA1, breast

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

A novel assay revealed that ribonucleotide reductase is functionally important for interstrand DNA crosslink repair

Keywords: ATR، ATM و Rad3 مرتبط است; ATM, Ataxia telangiectasia mutated; ATR, ATM and rad3-related; BCA, bicinchoninic acid; Chk1, checkpoint kinase 1; DDR, DNA damage response/repair; DMSO, dimethyl sulfoxide; EDTA, ethylenediaminetetraacetic acid; FBS, fetal bovine serum; HEPES, 2-[4-(2-hy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of p53/ATM-dependent DNA damage signaling pathway by shiga toxin in mammalian cells

Keywords: ATR، ATM و Rad3 مرتبط است; p53; ATM; Shiga toxin; Signaling; Mammalian cell; ApoptosisATM, Ataxia telangiectasia mutant; ATR, ATM and Rad3-related; STX, Shiga toxin; ShET, Shigella enterotoxin; CAD, Caspase activated DNase; PCR, Polymerase chain reaction; VTEC, Verotoxin producing

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Reversion of the ErbB malignant phenotype and the DNA damage response

Keywords: ATR، ATM و Rad3 مرتبط است; ARG, amphiregulin; ATM, ataxia telangiectasia mutated; ATR, ATM and Rad3-related; BRCA1/2, breast cancer type 1/2 susceptibility protein; DNA-PK, DNA dependent protein kinase; DSB, double strand break; EGF, epidermal growth factor; EGFR, epidermal growth

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibition of checkpoint kinase 1 sensitizes lung cancer brain metastases to radiotherapy

Keywords: ATR، ATM و Rad3 مرتبط است; Chk1; Chk1inhibitor; AZD7762; Radiosensitivity; DNA damage checkpointDSB, double-stranded DNA break; Chk1, checkpoint kinase 1; ATM, ataxia-telangiectasia mutated; ATR, ATM and Rad3-related; IR, ionizing radiation; MBT, metastatic brain tumor; shRNA, smal

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Valproic acid-induced DNA damage increases embryonic p27KIP1 and caspase-3 expression: A mechanism for valproic-acid induced neural tube defects

Keywords: ATR، ATM و Rad3 مرتبط است; ATM, ataxia telangiectasia mutated; ATR, ATM and RAD3-related; BSA, bovine serum albumin; DAB, 3,3-diaminobenzidine; DNAPKcs, DNA-protein kinase catalytic subunit; DSB, double strand break; GD, gestational day; NTD, neural tube defect; γH2AX, phosphorylat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells

Keywords: ATR، ATM و Rad3 مرتبط است; Mevalonate pathway; Small GTPases; Anticancer drugs; DNA damage response (DDR); Sarcoma cellsATM, ataxia telangiectasia mutated; ATR, ATM and Rad3-related; Chk, checkpoint kinase; DDR, DNA damage response; ERK, extracellular regulated kinase; H2AX, histon

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Cellular distribution and subcellular localization of spatacsin and spastizin, two proteins involved in hereditary spastic paraplegia

Keywords: ATR، ATM و Rad3 مرتبط است; AR, autosomal recessive; ATM, ataxia telangiectasia mutated; ATR, ATM and Rad3-related; CNS, central nervous system; EM, electron microscopy; HSP, hereditary spastic paraplegias; SPG, spastic paraplegia gene; TCC, thin corpus callosumSpastic paraplegia; S

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Inter-individual variation in DNA double-strand break repair in human fibroblasts before and after exposure to low doses of ionizing radiation

Keywords: ATR، ATM و Rad3 مرتبط است; A-T, ataxia-telangiectasia; ATM, ataxia-telangiectasia mutated; ATR, ATM and Rad3-related; LIG, ligase; DSB, double-strand break; FANC, Fanconi anemia; IR, ionizing radiation; NBN, nibrin; NBS, Nijmegen breakage syndrome; NHEJ, nonhomologous end joiningγ-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

MAPK regulate p53-dependent cell death induced by benzo[a]pyrene: Involvement of p53 phosphorylation and acetylation

Keywords: ATR، ATM و Rad3 مرتبط است; AhR, aryl hydrocarbon receptor; ANF, α-naphthoflavone; ATM, ataxia-telangiectasia mutated; ATR, ATM and Rad3-related; BaP, benzo[a]pyrene; BPDE-I, r-7,t-8-dihydrodiol-t-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene; CYP1A1, cytochrome P450 1A1; DNA-PK, DNA-d

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Bloom's Syndrome Helicase and Mus81 are Required to Induce Transient Double-strand DNA Breaks in Response to DNA Replication Stress

Keywords: ATR، ATM و Rad3 مرتبط است; APH, aphidicolin; ATM, ataxia telangiectasia mutated; ATR, ATM and Rad3-related; ATRkd, ATR kinase dead; BLM, Bloom; BS, Bloom's syndrome; BSA, bovine serum albumin; BrdU, bromodeoxyuridine; CldU, 5-chloro-2′-deoxyuridine; DMEM, Dulbecco's modified Eagle'

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Excess ribonucleotide reductase R2 subunits coordinate the S phase checkpoint to facilitate DNA damage repair and recovery from replication stress

Keywords: ATR، ATM و Rad3 مرتبط است; RNR, ribonucleotide reductase; ATM, ataxia telangiectasia-mutated; ATR, ATM and Rad3-related; DSBs, DNA double-stranded breaks; IR, ionizing radiation; chk1, checkpoint kinase 1; γ-H2Ax, phosphorylated-histone 2Ax; sh/siRNA, short hairpin/short interferen

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

p21Cip1/Waf1/Sdi1 protects against hyperoxia by maintaining expression of Bcl-XL

Keywords: ATR، ATM و Rad3 مرتبط است; ATM, ataxia–telangiectasia mutated; ATR, ATM and Rad3-related; PCNA, proliferating cell nuclear antigen; PUMA, p53 up-regulated modulator of apoptosis; ROS, reactive oxygen species; wt, wild typeFree radicals

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

UV-induced RPA phosphorylation is increased in the absence of DNA polymerase η and requires DNA-PK

Keywords: ATR، ATM و Rad3 مرتبط است; ATM, ataxia-telangiectasia mutated; ATR, ATM and Rad3-related; ATRIP, ATR-interacting protein; CPD, cyclobutane pyrimidine dimer; DNA-PK, DNA-dependent protein kinase; Polη, polymerase η; RPA, replication protein A; XPV, xeroderma pigmentosum variantPolη;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه