CHEK again: Revisiting the development of CHK1 inhibitors for cancer therapy
Keywords: CHK1; Checkpoint kinase 1; DNA replication; WEE1; DNA damage responseATM, ataxia-telangiectasia mutated; ATR, ATM and Rad3 related; CHK1, Checkpoint Kinase 1; CHK2, Checkpoint Kinase 2; CDKs, Cyclin-dependent kinases; DDK, DBF4/DRF1-dependent CDC7 kinase;