Keywords: مهار خودکار; Autoinhibition; H3 receptor; H1 receptor; Retrograde tracing; Aminergic neurons; Patch-clamp; Single cell RT-PCR;
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Keywords: مهار خودکار; SAXS, small-angle X-ray scattering; SIC, selected-ion chromatogramDNA methylation; DNMT1; epigenetics; allosteric regulation; autoinhibition
Keywords: مهار خودکار; RLK; receptor-like kinase; RTK; receptor tyrosine kinase; IRAK; interleukin-1 receptor-associated kinase; SYMRK; Symbiosis Receptor Kinase; WT; wild-type; Trx; thioredoxin; CD; circular dichroism; Gatekeeper tyrosine; Autophosphorylation; Autoinhibition;
Keywords: مهار خودکار; CaM; calmodulin; AID; autoinhibitory domain; CnB; calcineurin regulatory B subunit; can; calcineurin catalytic A subunit; Ca2Â +; calcium; BBH; CnB binding domain; CBD; CaM binding domain; SAXS; small angle X-ray scattering; Activation; Autoinhibition; Ca
Keywords: مهار خودکار; SMYD family; Autoinhibition; MD simulations; Energy correlation; Normal mode analysis
Structural conservation of the autoinhibitory domain in SUN proteins
Keywords: مهار خودکار; LINC complex; SUN proteins; SUN1; Autoinhibition;
Structure-based design of competitive ligands to target Spon2 in gastric cancer: An integration of molecular modeling and in vitro assay
Keywords: مهار خودکار; Spon2; Rational molecular design; Peptide ligand; Autoinhibition; Gastric cancer;
The ataxia related G1107D mutation of the plasma membrane Ca2Â + ATPase isoform 3 affects its interplay with calmodulin and the autoinhibition process
Keywords: مهار خودکار; Calcium signaling; Plasma membrane calcium ATPases; X-linked cerebellar ataxia; Calmodulin; Autoinhibition;
Structural and biochemical studies of the PDGFRA kinase domain
Keywords: مهار خودکار; PDGFRA; Crystal structure; Autoinhibition; D842V; Drug-resistance;
Cool-temperature-mediated activation of phospholipase C-γ2 in the human hereditary disease PLAID
Keywords: مهار خودکار; PLC; inositol-phospholipid-specific phospholipase C; SH2; Src homology domain 2; SH3; Src homology domain 3; PH; pleckstrin homology domain; spPH; split PH domain; PCI; phospholipase C inhibitor peptide; Rac; Ras-related C3 botulinum toxin substrate; BCR;
C-terminal truncation of Noxa1 greatly enhances its ability to activate Nox2 in a pure reconstitution system
Keywords: مهار خودکار; Noxa1; Noxo1; Truncation; NADPH oxidase; Nox; Superoxide; Autoinhibition;
Arf GTPase regulation through cascade mechanisms and positive feedback loops
Keywords: مهار خودکار; Arf GTPase; Rab GTPase; Guanine nucleotide exchange factor; Autoinhibition; Positive feedback loop;
Structure and function of a bacterial Fasciclin I Domain Protein elucidates function of related cell adhesion proteins such as TGFBIp and periostin
Keywords: مهار خودکار; NMR structure; Cell adhesion; Biofilm; Autoinhibition; Domain interfaceFAS, fasciclin; Fdp, Fasciclin I Domain Protein
Basic NeuroscienceMicrodialysis probes alter presynaptic regulation of dopamine terminals in rat striatum
Keywords: مهار خودکار; Dopamine; Autoinhibition; Microdialysis probe; Voltammetry; Hypersensitivity; Injury;
Extensions of PSD-95/discs large/ZO-1 (PDZ) domains influence lipid binding and membrane targeting of syntenin-1
Keywords: مهار خودکار; PDZ; Phospholipids; Electrostatic interactions; Autoinhibition; Membrane targeting; Surface plasmon resonance
5-HT1B receptor regulation of serotonin (5-HT) release by endogenous 5-HT in the substantia nigra
Keywords: مهار خودکار; autoreceptor; basal ganglia; fast-scan cyclic voltammetry; autoinhibition; substantia nigra pars reticulata; synaptic transmission[5-HT]o, extracellular concentration of 5-HT; CFM, carbon-fibre microelectrode; DA, dopamine; DRN, dorsal raphé nucleus; FCV,
Gαq allosterically activates and relieves autoinhibition of p63RhoGEF
Keywords: مهار خودکار; AF; Alexa Fluor 532; Dbs; Dbl's big sister; DH; Dbl homology; FCPIA; Flow cytometry protein interaction assay; FP; Fluorescence polarization; GFP; Green fluorescent protein; GRK; G protein-coupled receptor kinase; GPCR; G protein-coupled receptor; MFI; Me
Structural insights into the inhibited states of the Mer receptor tyrosine kinase
Keywords: مهار خودکار; Mer; MerTK; Kinase; Structure; Autoinhibition; Screen; Chemical probe;
Ligand-induced ErbB receptor dimerization
Keywords: مهار خودکار; Epidermal growth factor receptor; Receptor tyrosine kinase; ErbB receptor; Cooperativity; Receptor dimerization; Crystal structure; Heterodimer; Autoinhibition; Ligand binding; Allostery
Assembly of the RFX complex on the MHCII promoter: Role of RFXAP and RFXB in relieving autoinhibition of RFX5
Keywords: مهار خودکار; RFX; Gene regulation; MHCII; DNA binding assay; Autoinhibition
New Insights into the Autoinhibition Mechanism of Glycogen Synthase Kinase-3β
Keywords: مهار خودکار; GSK-3, glycogen synthase kinase-3; CREB, cAMP response element binding protein; WT, wild typeGSK-3; pseudosubstrate; autoinhibition; docking analysis
Expression, purification, and characterization of a structurally disordered and functional C-terminal autoinhibitory domain (AID) of the 70Â kDa 40S ribosomal protein S6 kinase-1 (S6K1)
Keywords: مهار خودکار; Custom gene synthesis; Intrinsic disorder; Disordered proteins; Autoinhibition; Phosphoinositide-dependent protein kinase-1; PDK1; Proteolysis inhibition; Minimal media;
The carboxyl terminal tyrosine 417 residue of NOK has an autoinhibitory effect on NOK-mediated signaling transductions
Keywords: مهار خودکار; RPTK; NOK; RAS/MAPK; STATs; Autoinhibition
The Crystal Structures of Human Calpains 1 and 9 Imply Diverse Mechanisms of Action and Auto-inhibition
Keywords: مهار خودکار; β-ME, β-mercaptoethanol; sLY-AMC, succinyl-Leu-Tyr-(7-amino-4-methylcoumarin)cysteine protease; structure; peptidase; active site; autoinhibition
Mechanism of tail-mediated inhibition of kinesin activities studied using synthetic peptides
Keywords: مهار خودکار; Kinesin; Microtubule; Autoinhibition; Peptide; In vitro motility; ATPase
Role of the PH domain in regulating in vitro autophosphorylation events required for reconstitution of PDK1 catalytic activity
Keywords: مهار خودکار; Phosphoinositide-dependent protein kinase-1; Phosphoinositide signaling; Protein kinase; Autoinhibition; Autophosphorylation; Oligomerization; Phosphopeptide mapping; Sedimentation equilibrium; Agc kinases