دانلود مقالات ISI درباره Azd6244 + ترجمه فارسی

How to MEK the best of uveal melanoma: A systematic review on the efficacy and safety of MEK inhibitors in metastatic or unresectable uveal melanoma

Keywords: AZD6244; Binimetinib; MEK162; MEK inhibitor; Ocular melanoma; Selumetinib; Sotrastaurin; Trametinib; Uveal melanoma; Uveal neoplasms;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Study Design and Rationale for a Randomized, Placebo-Controlled, Double-Blind Study to Assess the Efficacy and Safety of Selumetinib in Combination With Docetaxel as Second-Line Treatment in Patients With KRAS-Mutant Advanced Non-Small Cell Lung Cancer (S

Keywords: Advanced NSCLC; AZD6244; MEK1/2; Metastatic disease; Phase III;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Simultaneous suppression of the MAP kinase and NF-κB pathways provides a robust therapeutic potential for thyroid cancer

Keywords: MAPK; NF-κB; Thyroid cancer; AZD6244; Bortezomib

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Dual blockade of PI3K/AKT/mTOR (NVP-BEZ235) and Ras/Raf/MEK (AZD6244) pathways synergistically inhibit growth of primary endometrioid endometrial carcinoma cultures, whereas NVP-BEZ235 reduces tumor growth in the corresponding xenograft models

Keywords: Endometrioid endometrial cancer; Primary cell culture; Targeted therapy; NVP-BEZ235; AZD6244;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Synergistic inhibition of thyroid cancer by suppressing MAPK/PI3K/AKT pathways

Keywords: Thyroid cancer; AZD6244; GDC0941; Synergism; MAPK; PI3K/AKT

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Selective inhibition of extracellular signal-regulated kinases 1/2 blocks nerve growth factor to brain-derived neurotrophic factor signaling and suppresses the development of and reverses already established pain behavior in rats

Keywords: AZD6244; neuropathic pain; drug therapy; MEK inhibitor; NGF-BDNF signalingBDNF, brain-derived neurotrophic factor; CA-MEK1, constitutively active-MEK1; CCI, chronic constriction injury; DRG, dorsal root ganglion; EDTA, ethylenediaminetetraacetic acid; ERK

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Targeting ERK1/2 activation and proliferation in human primary schwannoma cells with MEK1/2 inhibitor AZD6244

Keywords: Schwannoma; Merlin-deficient tumors; Targeted therapy; AZD6244;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

A Phase II, Open-Label, Randomized Study to Assess the Efficacy and Safety of AZD6244 (ARRY-142886) Versus Pemetrexed in Patients with Non-small Cell Lung Cancer Who Have Failed One or Two Prior Chemotherapeutic Regimens

Keywords: AZD6244; Non-small cell lung cancer; Phase II; Clinical trial; MEK inhibitor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه