The effect of chronic mild stress on tumor-bearing rats’ behavior and its mechanism
Keywords: Tumor; Depression; Chronic mild stress; Bcl-2; ERK1/2
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Molecular analysis and prognostic impact of the novel apoptotic gene BCL2L12 in gastric cancer
Keywords: BCL2L12; Real-time PCR; Biomarkers; Gastric cancer; BCL-2; Apoptosis;
microRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells
Keywords: microRNA; miR-195; Apoptosis; Bcl-2; Colorectal cancer
Hypoxia-induced Bcl-2 expression in endothelial cells via p38 MAPK pathway
Keywords: Hypoxia; Bcl-2; siRNA; Endothelial cells; Angiogenesis;
Thai Acanthamoeba isolate (T4) induced apoptotic death in neuroblastoma cells via the Bax-mediated pathway
Keywords: Acanthamoeba; T4 genotype; Apoptosis; Caspase; Bax; Bcl-2
Hydrogen peroxide induces apoptosis through the mitochondrial pathway in rat Schwann cells
Keywords: Schwann cells; Hydrogen peroxide; Apoptosis; Cytochrome c; Bax; Bcl-2
Expressions of the anti-apoptotic genes Bag-1 and Bcl-2 in colon cancer and their relationship
Keywords: Colorectal cancer; Bag-1; Bcl-2; Apoptosis
Non-Hodgkin lymphoma (NHL) subtypes defined by common translocations: Utility of fluorescence in situ hybridization (FISH) in a case–control study
Keywords: FISH; Translocation; Lymphoma; t(14 ;18); bcl-2
Non-receptor tyrosine kinase Etk is involved in the apoptosis of small cell lung cancer cells
Keywords: Small cell lung cancer; Etk; Apoptosis; Bcl-2; Bcl-XL; p53
Tissue microarray constructs to predict a response to chemoradiation in rectal cancer
Keywords: TMA, tissue microarray; IHC, immunohistochemistry; IR, ionizing radiation; NPV, negative predictive value; PPV, positive predictive value; pCR, pathological complete responseBAX; Bcl-2; MIB; Number of lymph nodes; Pathological complete response; p53
Pamidronate inhibits antiapoptotic bcl-2 expression through inhibition of the mevalonate pathway in prostate cancer PC-3 cells
Keywords: Bcl-2; Pamidronate; Bisphosphonate; Prostate cancer; Mevalonate pathway; Rap1
The selective progesterone receptor modulator CDB4124 inhibits proliferation and induces apoptosis in uterine leiomyoma cells
Keywords: Uterine leiomyoma; myometrium; antiprogestin; proliferation; apoptosis; PCNA; PARP; Bcl-2
Immunoexpression of Ki67, proliferative cell nuclear antigen, and Bcl-2 proteins in a case of ameloblastic fibrosarcoma
Keywords: Ameloblastic fibrosarcoma; Odontogenic tumors; Bcl-2; Ki67; PCNA
Apoptosis-related factors p53, bcl-2 and the defects of force transmission in dilated cardiomyopathy
Keywords: Desmin; N-cadherin; Bcl-2; p53; Dilated cardiomyopathy
Clinicopathologic correlation of beclin-1 and bcl-2 expression in human breast cancer
Keywords: Breast cancer; Beclin-1; Bcl-2
The prognostic role of Bcl-2 mRNA expression in curatively resected non-small cell lung cancer (NSCLC)
Keywords: Lung cancer; NSCLC; Prognostic; Biomarker; Bcl2; Bcl-2; Factors; Non-tumorous lung tissue; Non-small lung cancer
Targeting Bcl-2-Mediated Cell Death as a Novel Therapy in Pancreatic Cancer
Keywords: autophagy; Bcl-2; BH-3; apoptosis; pancreatic cancer; beclin 1
Ceramide channels and their role in mitochondria-mediated apoptosis
Keywords: MOM; mitochondrial outer membrane; Channel; Outer membrane; Mitochondrion; Bcl-2; Pore; Self-assembly;
Induction of cell cycle arrest and apoptosis by the ethyl acetate fraction of Kalopanax pictus leaves in human colon cancer cells
Keywords: Apoptosis; Bcl-2; Cell cycle; Kalopanax pictus leaf; Reactive oxygen species
2-(-2-benzofuranyl)-2-imidazoline induces Bcl-2 expression and provides neuroprotection against transient cerebral ischemia in rats
Keywords: 2-BFI; Bcl-2; Cell death; Rat; Cerebral ischemia; Stroke; Brain
Reduction of intersectin1-s induced apoptosis of human glioblastoma cells
Keywords: ITSN1-s; Apoptosis; Glioblastoma; Bcl-2; Akt;
Bcl-2 and Caspase 3 mRNA levels in the testes of gudgeon, Gobio gobio, exposed to ethinylestradiol (EE2)
Keywords: Bcl-2; Caspase 3; Ethinylestradiol; Early spermatogenesis
Goniothalamin-induced oxidative stress, DNA damage and apoptosis via caspase-2 independent and Bcl-2 independent pathways in Jurkat T-cells
Keywords: Goniothalamin; DNA damage; Oxidative stress; Caspase-2; Bcl-2;
Research ArticleThe let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma
Keywords: Liver; Mcl-1; Bcl-2; Tumour; Epigenetic; miRNA; microRNA; 3â²UTR; 3â²-untranslated region; mRNA; messenger RNA; HCC; hepatocellular carcinoma; CDK; cyclin-dependent kinase; DMEM; Dulbecco's modified Eagle medium; RT; reverse transcription; PCR; polyme
Prognostic Significance of BAD and AIF Apoptotic Pathways in Diffuse Large B-Cell Lymphoma
Keywords: BCL-2; CHOP; Clinical stages; Non-Hodgkin lymphoma; PP1α
The coffee diterpene kahweol sensitizes TRAIL-induced apoptosis in renal carcinoma Caki cells through down-regulation of Bcl-2 and c-FLIP
Keywords: Kahweol; TRAIL; Apoptosis; Caki; Bcl-2; c-FLIP
Panaxynol protects cortical neurons from ischemia-like injury by up-regulation of HIF-1α expression and inhibition of apoptotic cascade
Keywords: Panaxynol; Hypoxia; HIF-1α; Caspase-3; Bcl-2; Bax
Sulforaphane protects ischemic injury of hearts through antioxidant pathway and mitochondrial KATP channels
Keywords: Sulforaphane; Heart; Ischemia; Mitochondria; KATP channel; Atrial natriuretic peptide; Apoptosis; Bcl-2; Bax; Caspase-3; Catalase; Superoxide dismutase; Heme oxygenase-1
Effects of 17β-estradiol replacement on the apoptotic effects caused by ovariectomy in the rat hippocampus
Keywords: Bcl-2; Bax; Hippocampus; 17β-estradiol; Ovariectomy
The fourth isoform of the adenine nucleotide translocator inhibits mitochondrial apoptosis in cancer cells
Keywords: ADP/ATP carrier; Bcl-2; Cell death; Mitochondria
The protective effect of 17β-estradiol postconditioning against hypoxia/reoxygenation injury in human gastric epithelial cells
Keywords: 17β-estradiol; Human gastric epithelial cells; Hypoxia/reoxygenation; Pharmacological postconditioning; Apoptosis; Bcl-2; Bax
Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells
Keywords: EGCG; Tea polyphenols; miRNA; Bcl-2; Apoptosis
Circulating nucleic acids in type 1 diabetes may modulate the thymocyte turnover rate
Keywords: Type 1 diabetes; Circulating nucleic acids; PCNA; Bcl-2; Bax; NF-κB rat thymocytes
Expression of Bcl-2 predicts outcome in locally advanced non-small cell lung cancer patients treated with cisplatin-based concurrent chemoradiotherapy
Keywords: Non-small cell lung cancer (NSCLC); Bcl-2; Chemoradiotherapy; Prognosis
BCL2 gene polymorphism could predict the treatment outcomes in acute myeloid leukemia patients
Keywords: Bcl-2; Single nucleotide polymorphism; Acute myeloid leukemia
Bisphenol A and estradiol are equipotent in antagonizing cisplatin-induced cytotoxicity in breast cancer cells
Keywords: Breast cancer cells; Cisplatin; Bisphenol A; Estradiol; Estrogen receptors; Bcl-2
Single-prolonged stress induces apoptosis in the amygdala in a rat model of post-traumatic stress disorder
Keywords: Post-traumatic stress disorder; Amygdala; Apoptosis; Bax; Bcl-2; TUNEL; Flow cytometry
Delphinidin attenuates stress injury induced by oxidized low-density lipoprotein in human umbilical vein endothelial cells
Keywords: Atherosclerosis; Delphinidin; Oxidized low-density lipoprotein; Human vascular endothelial cells; Bcl-2; Bax;
Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death
Keywords: Neurodegeneration; Neuronal cell death; Glutamate; Oxidative stress; Mitochondria; Fission and fusion; Bid; Apoptosis inducing factor; Mitochodondrial fission; Mitochondrial membrane potential; Apoptosis; Bcl-2
Green tea averts age-dependent decline of hippocampal signaling systems related to antioxidant defenses and survival
Keywords: Aging; Green tea; Catechins; Glutathione; Antioxidant enzymes; CREB; BDNF; Bcl-2; Hippocampal formation; Rat; Free radicals
Opposing actions of the progesterone metabolites, 5α-dihydroprogesterone (5αP) and 3α-dihydroprogesterone (3αHP) on mitosis, apoptosis, and expression of Bcl-2, Bax and p21 in human breast cell lines
Keywords: Breast cancer; Apoptosis; Progesterone metabolites; Cell proliferation; Bcl-2; Bax; p21; MCF-7; MDA-MB231; MCF-10A; T47D
Influence of cholesterol and fish oil dietary intake on nitric oxide-induced apoptosis in vascular smooth muscle cells
Keywords: Apoptosis; Vascular smooth muscle cells; Atherosclerosis; Bcl-2; Bax; C-myc; P53; Nitric oxide
Noxa is necessary for hydrogen peroxide-induced caspase-dependent cell death
Keywords: RT-PCR, reverse transcription polymerase chain reaction; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; CRE, cAMP response element; ATF, activating transcription factor; CREB, cAMP response element-binding proteinHydrogen peroxide; Apoptosis; Bcl-2; Nox
Protein kinase A activators and the pan-PPAR agonist tetradecylthioacetic acid elicit synergistic anti-leukaemic effects in AML through CREB
Keywords: Protein kinase A; Cyclic AMP; Tetradecylthioacetic acid; Acute myelogenous leukaemia; Bcl-2; Inducible cAMP early repressor; Peroxisome proliferator-activated receptor; cAMP response element binding;
Mechanism of retinal ganglion cells death in secondary degeneration of the optic nerve
Keywords: glaucoma; bcl-2; apoptosis; secondary degeneration; optic nerve
AT-101, a Pan-Bcl-2 Inhibitor, Leads to Radiosensitization of Non-small Cell Lung Cancer
Keywords: Apoptosis; Bcl-2; Lung cancer; Radiotherapy
Levonorgestrel inhibits proliferation and induces apoptosis in uterine leiomyoma cells
Keywords: Uterine leiomyoma; Levonorgestrel (LNG); Cell proliferation and apoptosis; IGF-1; Bcl-2; Survivin; Caspase 3; p38 MAPK signal pathway
Cisplatin induces duplex 3′ overhangs and 5′ blunt ends in epididymal epithelium in a Bax-dependent manner without any protection from l-ascorbic acid
Keywords: Anticancer drug; Oxidative stress; In situ oligo ligation; DNA strand break; p53; Bax; Bcl-2; Reproductive toxicity
Ganoderma lucidum induced apoptosis in NB4 human leukemia cells: Involvement of Akt and Erk
Keywords: Apoptosis; Bax; Bcl-2; Ganoderma lucidum (Curtis) P. Karst.; Ganodermataceae Donk; Leukemia; p53
β2-Agonist modulates epithelial gene expression involved in the T- and B-cell chemotaxis and induces airway sensitization in human isolated bronchi
Keywords: AP1; activator protein 1; Bcl-2; B-cell lymphoma protein 2; CCL2/MCP-1; monocyte chemoattractant protein-1; CCL20/MIP-3α; macrophage inflammatory protein 3α; CCN4; connective tissue growth factor; c-fos; v-fos FBJ murine osteosarcoma viral oncogene homo