دانلود مقالات ISI درباره بتا آمیلوئید + ترجمه فارسی

Una revisión de los avances en la terapéutica de la enfermedad de Alzheimer: estrategia frente a la proteína β-amiloide

Keywords: بتا آمیلوئید; Alzheimer; Beta-amiloide; Beta-secretasa; Gamma-secretasa; Hipótesis amiloidea; Alzheimer disease; Beta-amyloid; Beta-secretase; Gamma-secretase; Amyloid hypotheses;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of safflower yellow on beta-amyloid deposition and activation of astrocytes in the brain of APP/PS1 transgenic mice

Keywords: بتا آمیلوئید; Alzheimer's disease; Safflower yellow; Beta-amyloid; Astrocytes;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

The Protective Effects of IGF-I against β-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A

Keywords: بتا آمیلوئید; AC; adenylyl cyclase; AD; Alzheimer's disease; Akt; protein kinase B; Aβ; beta-amyloid; BDNF; brain-derived neurotrophic factor; CCK; cholecystokinin, CRE, cyclic AMP response element; CREB; CRE-binding protein; GABA; γ-aminobutyric acid; GFAF; glial

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer's agents: Structure-activity relationship study of Arg-mimetic region

Keywords: بتا آمیلوئید; Glutaminyl cyclase inhibitor; Alzheimer's disease; Beta-amyloid;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

β-amyloid deposition is associated with gait variability in usual aging

Keywords: بتا آمیلوئید; Beta-amyloid; Usual aging; Gait variability; Gait characteristics;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and biological evaluation of 3-piperazinecarboxylate sarsasapogenin derivatives as potential multifunctional anti-Alzheimer agents

Keywords: بتا آمیلوئید; Sarsasapogenin derivatives; Alzheimer's disease; Antioxidation; Antiinflammation; Structure-activity relationship; Beta-amyloid;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibitive Effect of Resveratrol on the Inflammation in Cultured Astrocytes and Microglia Induced by Aβ1-42

Keywords: بتا آمیلوئید; AD; Alzheimer's disease; Aβ; beta-amyloid; APC; antigen-presenting cell; BACE1; β-site APP cleaving enzyme 1; BBB; blood-brain barrier; CCK; cell-counting kit; CD40; cluster of differentiation 40; CNS; central nervous system; DAPI; 4′,6-diamidino-

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Increasing beta-amyloid deposition in cognitively healthy aging predicts nonlinear change in BOLD modulation to difficulty

Keywords: بتا آمیلوئید; Aging; Beta-amyloid; fMRI; Preclinical Alzheimer's disease; Nonlinear BOLD activation; Cognition; N-Back;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Simultaneous quantitative susceptibility mapping and Flutemetamol-PET suggests local correlation of iron and β-amyloid as an indicator of cognitive performance at high age

Keywords: بتا آمیلوئید; PET; MRI; Beta-amyloid; Iron; QSM; Aging;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Aβ propagation and strains: Implications for the phenotypic diversity in Alzheimer's disease

Keywords: بتا آمیلوئید; Beta-amyloid; Prion propagation; Strains; Alzheimer's disease; Neurodegeneration; Protein aggregation;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Cyclometalated iridium(III) luminescent complexes in therapy and phototherapy

Keywords: بتا آمیلوئید; A2058; human metastatic melanoma cell; A2780; human ovarian carcinoma cell; A2780cisR; cisplatin-resistant A2780; A375; human melanoma cell; A549; human lung adenocarcinoma epithelial cell; A549R; cisplatin-resistant A549 cell; Aβ; beta-amyloid; acac; ac

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Membrane-lipid homeostasis in a prodromal rat model of Alzheimer's disease: Characteristic profiles in ganglioside distributions during aging detected using MALDI imaging mass spectrometry

Keywords: بتا آمیلوئید; AD; Alzheimer's Disease; Aβ; Beta-amyloid; GSL; Glycosphingolipids; IMS; Imaging Mass Spectrometry; MALDI; Matrix-Assisted Laser Desorption Ionization; Tg; Transgenic; Wt; Wild type; Gangliosides; MALDI imaging mass spectrometry; Aging brain; Transgenic

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of NPY-Y2 receptors ameliorates disease pathology in the R6/2 mouse and PC12 cell models of Huntington's disease

Keywords: بتا آمیلوئید; Aβ; beta-amyloid; ABC; avidin-biotin complex; BBB; blood brain barrier; BDNF; brain derived neurotrophic factor; BSA; bovine serum albumin; CREB; cAMP response element binding protein; cDNA; complementary deoxyribonucleic acid; DAB, 3; 3-diaminobenzidine

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

CSF biomarkers β-amyloid, tau proteins and a-synuclein in the differential diagnosis of Parkinson-plus syndromes

Keywords: بتا آمیلوئید; Aβ42; beta-amyloid; AD; Alzheimer's disease; ANCOVA; analysis of covariance; ANOVA; analysis of variance; a-syn; a-synuclein; CBD; Corticobasal degeneration; CBS; corticobasal syndrome; CBS-AD; corticobasal syndrome with underlying AD pathology; CBS-non-

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Research articleGalantamine alleviates senescence of U87 cells induced by beta-amyloid through decreasing ROS production

Keywords: بتا آمیلوئید; Alzheimer's disease; Beta-amyloid; U87 cell line; Galantamine; ROS; p53;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Role of the adhesion molecule F3/Contactin in synaptic plasticity and memory

Keywords: بتا آمیلوئید; Cell adhesion molecules; F3/Contactin; Synaptic plasticity; Long-term potentiation; Memory; CREB; Aging; Beta-amyloid; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease

Keywords: بتا آمیلوئید; Microglia; Neuroinflammation; Beta-amyloid; Neurodegeneration; Early-onset Alzheimer's disease; Late-onset Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Amyloid and tau PET demonstrate region-specific associations in normal older people

Keywords: بتا آمیلوئید; AD; Alzheimer's disease; Aβ; beta-amyloid; BPM; biological parametric mapping; CT; computed tomography; DVR; distribution volume ratio; FDR; false discovery rate; GM; gray matter; LBNL; Lawrence Berkeley National Laboratory; MMSE; mini-mental state exami

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Correlation of florbetaben PET imaging and the amyloid peptide Aß42 in cerebrospinal fluid

Keywords: بتا آمیلوئید; Alzheimer's disease; Biomarker; PET-tracer; Florbetaben; Beta-amyloid; Cerebrospinal fluid;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Research reportHippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models

Keywords: بتا آمیلوئید; AD; Alzheimer's disease; CFM; contextual fear memory; Ntg; non-transgenic; IPA; ingenuity pathway analysis; Aβ; beta-amyloid; Proteomics; Aging; Alzheimer's disease; Ion channels; Cognition;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Cyanidin-3-O-glucoside attenuates amyloid-beta (1-40)-induced oxidative stress and apoptosis in SH-SY5Y cells through a Nrf2 mechanism

Keywords: بتا آمیلوئید; Cyanidin-3-O-glucoside; SH-SY5Y cell; Aβ1-40; Oxidative stress; Apoptosis; NrF2/ARE activation; ARE; antioxidant response element; C3G; cyanidin-3-O-glucoside; Aβ; beta-amyloid; ROS; reactive oxygen species; GSH-Px; glutathione peroxidase; H2O2; hydroge

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Cannabidiol: State of the art and new challenges for therapeutic applications

Keywords: بتا آمیلوئید; (5-HT)1A; 5-hydroxytryptamine receptor;  ∆9-THC; delta-9-tetrahydrocannabinol; 2-AG; 2-arachidonoylglycerol; A2A; adenosine receptor; AEA; anandamide; ALI; acute lung injury; Aml-1; acute myeloid leukemia; APP; amyloid precursor protein; AR; androgen r

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Clinical validity of cerebrospinal fluid Aβ42, tau, and phospho-tau as biomarkers for Alzheimer's disease in the context of a structured 5-phase development framework

Keywords: بتا آمیلوئید; Cerebrospinal fluid; Beta-amyloid; Tau; Phosphorylated tau; Biomarker development; Early diagnosis; Biomarker-based diagnosis; Alzheimer's disease; 5-Phases;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Self-reported traumatic brain injury and in vivo measure of AD-vulnerable cortical thickness and AD-related biomarkers in the ADNI cohort

Keywords: بتا آمیلوئید; Traumatic brain injury; Alzheimer's disease; Cortical thickness; CSF biomarkers; Beta-amyloid; Tau;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Increased Levels of the Bullous Pemphigoid BP180 Autoantibody Are Associated with More Severe Dementia in Alzheimer's Disease

Keywords: بتا آمیلوئید; Aβ1-42; beta-amyloid; AD; Alzheimer's disease; BP; bullous pemphigoid; CSF; cerebrospinal fluid; IF; immunofluorescence; MMSE; mini-mental state examination; NC16A; noncollagenous 16A; p-tau181; hyperphosphorylated tau;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

PET Imaging for Early Detection of Alzheimer's Disease

Keywords: بتا آمیلوئید; Alzheimer's disease; PET imaging; Synaptic density; Beta-amyloid; Tau protein; Cholinergic; Inflammation; SV2A;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

Zinc transporter 3 (ZnT3) and vesicular zinc in central nervous system function

Keywords: بتا آمیلوئید; Zincergic; Gluzinergic; Synaptic plasticity; Experience-dependent plasticity; Synaptic zinc; SLC30A3, Zn2+; 2-AG; 2-arachidonolylglycerol; Aβ; beta-amyloid; AP-3; adaptor protein 3; BDNF; brain-derived neurotrophic factor; BNST; bed nucleus of the stria

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

Design and synthesis of new theranostic agents for near-infrared imaging of β-amyloid plaques and inhibition of β-amyloid aggregation in Alzheimer's disease

Keywords: بتا آمیلوئید; Alzheimer's disease; Beta-amyloid; Cytotoxicity; NIRF imaging; Inhibitors; Theranostic agents;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits

Keywords: بتا آمیلوئید; Neurotrophin; Plasminogen; Beta-amyloid; Tau hyperphosphorylation; Memory;

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2017 سفارش ترجمه

Neuroprotective effects of honokiol against beta-amyloid-induced neurotoxicity via GSK-3β and β-catenin signaling pathway in PC12 cells

Keywords: بتا آمیلوئید; Honokiol; Beta-amyloid; Apoptosis; Oxidative stress; GSK-3β; PC12 cells

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewThe UPR and synaptic dysfunction in neurodegeneration

Keywords: بتا آمیلوئید; ATF4; Activating Transcription Factor 4; ATF6; Activating Transcription Factor 6; Aβ; Beta-Amyloid; BiP; Binding immunoglobulin Protein; CHOP; C/EBP Homologous Protein; CREB; Cyclic AMP Response Element Binding Protein; eIF2; Eukaryotic Initiation Factor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Visual and fluorescent assays for selective detection of beta-amyloid oligomers based on the inner filter effect of gold nanoparticles on the fluorescence of CdTe quantum dots

Keywords: بتا آمیلوئید; Beta-amyloid; Inner filter effect; Fluorescent biosensor; Visual assay; Quantum dots; Gold nanoparticles;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportIcariin, a major constituent from Epimedium brevicornum, attenuates ibotenic acid-induced excitotoxicity in rat hippocampus

Keywords: بتا آمیلوئید; AD; Alzheimer's disease; IBO; ibotenic acid; NMDA; N-methyl-d-aspartate; Aβ; beta-amyloid; MAPK; mitogen-activated protein kinase; Erk; extracellular-regulated kinase; JNK; c-Jun N-terminal kinase; ICA; icariin; ICV; intracerebroventricular; ANOVA; one-w

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Clinical and MRI models predicting amyloid deposition in progressive aphasia and apraxia of speech

Keywords: بتا آمیلوئید; Beta-amyloid; Primary progressive aphasia; Apraxia of speech; Volumetric MRI

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

A theranostic agent for in vivo near-infrared imaging of β-amyloid species and inhibition of β-amyloid aggregation

Keywords: بتا آمیلوئید; Beta-amyloid; Alzheimer's disease; NIR imaging; Inhibitor; Theranostic agent

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Early effects of Aβ1-42 oligomers injection in mice: Involvement of PI3K/Akt/GSK3 and MAPK/ERK1/2 pathways

Keywords: بتا آمیلوئید; Beta-amyloid; Cognitive impairment; Oxidative stress; Akt; ERK1/2; GSK3

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Hydrogen sulfide ameliorates learning memory impairment in APP/PS1 transgenic mice: A novel mechanism mediated by the activation of Nrf2

Keywords: بتا آمیلوئید; AD; Alzheimer's disease; Aβ; beta-amyloid; APP; beta-amyloid precursor protein; ARE; antioxidant response element; BACE1; β-site APP-cleaving enzyme 1; CBS; cystathionine-β-synthase; DG; dentate gyrus; GST; glutathione S-transferase; HO-1; heme oxygena

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Data supporting beta-amyloid dimer structural transitions and protein–lipid interactions on asymmetric lipid bilayer surfaces using MD simulations on experimentally derived NMR protein structures

Keywords: بتا آمیلوئید; Asymmetric lipid membranes; Protein structure on surfaces; Protein–lipid interactions; Protein aggregation; Beta-Amyloid

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Expression, purification, and characterization of human cystatin C monomers and oligomers

Keywords: بتا آمیلوئید; Aβ; beta-amyloid; AD; Alzheimer's disease; ANS; 8-anilinonaphthalene-1-sulfonic acid; catB; cathepsin B; CD; circular dichroism; cysC; cystatin C; DLS; dynamic light scattering; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; MES; 2-(N-morp

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

APOE ε4 moderates amyloid-related memory decline in preclinical Alzheimer's disease

Keywords: بتا آمیلوئید; Beta-amyloid; Apolipoprotein E; Cognitive decline; Preclinical Alzheimer's disease; Memory;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Research ReportLentiviral-mediated overexpression of nerve growth factor (NGF) prevents beta-amyloid [25-35]-induced long term potentiation (LTP) decline in the rat hippocampus

Keywords: بتا آمیلوئید; Hippocampus; Plasticity; LTP; Beta-amyloid; NGF; Neurotrophins; Lentivirus;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Photo-induced inhibition of Alzheimer's β-amyloid aggregation in vitro by rose bengal

Keywords: بتا آمیلوئید; Peptide self-assembly; Beta-amyloid; Photosensitizers; Inhibitors; Rose bengal

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Posterior cingulate γ-aminobutyric acid and glutamate/glutamine are reduced in amnestic mild cognitive impairment and are unrelated to amyloid deposition and apolipoprotein E genotype

Keywords: بتا آمیلوئید; Mild cognitive impairment; Alzheimer; Dementia; Magnetic resonance spectroscopy; MRS; GABA; Glx; Glutamate; Beta-amyloid; PiB; Posterior cingulate cortex; APOE;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Illite improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer׳s disease through Akt/CREB and GSK-3β phosphorylation in the brain

Keywords: بتا آمیلوئید; Alzheimer׳s disease; Illite; Beta-amyloid; Lithium; CREB; Akt;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

ShcC proteins: Brain aging and beyond

Keywords: بتا آمیلوئید; ShcC adaptor proteins; Signaling; Aging; Brain ischemia; Brain tumors; Immunity; Aβ; beta-amyloid; AD; Alzheimer's disease; Akt; protein kinase B (PKB); ALK; anaplastic lymphoma kinase (receptor tyrosine kinase); APP; alpha-amyloid precursor protein; ARD

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Icariin, a major constituent of flavonoids from Epimedium brevicornum, protects against cognitive deficits induced by chronic brain hypoperfusion via its anti-amyloidogenic effect in rats

Keywords: بتا آمیلوئید; Icariin; Permanent occlusion of bilateral common carotid arteries; Chronic cerebral hypoperfusion; Beta-amyloid; Transforming growth factor-β1 signaling

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Co-morbid beta-amyloid toxicity and stroke produce impairments in an ambiguous context task in rats without any impairment in spatial working memory

Keywords: بتا آمیلوئید; Alzheimer's disease (AD); Stroke; Beta-amyloid; Discriminative fear-conditioning to context; Morris water task; Acetylcholine; Hippocampus; Cue ambiguity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Down syndrome and Alzheimer's disease: Common pathways, common goals

Keywords: بتا آمیلوئید; Down syndrome; Alzheimer's disease; Dementia; Animal models; Ts65Dn; Drug discovery; Neuroinflammation; Cognitive assessment; Amyloid precursor protein; Beta-amyloid; Tau; Clinical trials; Biomarkers; Trisomy 21; ADNI; DS-Connect; Neuroimaging; Workshop;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Research ReportPaeoniflorin attenuates Aβ1-42-induced inflammation and chemotaxis of microglia in vitro and inhibits NF-κB- and VEGF/Flt-1 signaling pathways

Keywords: بتا آمیلوئید; Aβ; beta-amyloid; AD; Alzheimer׳s disease; CNS; central nervous system; PF; paeoniflorin; TNF-α; tumor necrosis factor α; IL-1β; interleukin 1β; IL-6; interleukin 6; NF-κB p65; nuclear factor kappa B subunit p65; IκBα; NF-κB inhibitor alpha; CXC

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Identifying Aβ-specific pathogenic mechanisms using a nematode model of Alzheimer's disease

Keywords: بتا آمیلوئید; Alzheimer's disease; Neurodegenerative disorders; Neurodegeneration; Beta-amyloid; Dementia;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه