
Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors
Keywords: Marinopyrroles; Mcl-1 and Bcl-xL antagonists; Apoptosis; Protein–protein interactionBcl-2, B-cell lymphoma 2; Bcl-xL, B-cell lymphoma extra large; BH3, Bcl-2 homology domain 3; Mcl-1, myeloid cell leukemia 1; MDA-MB-468, breast cancer cell line; SAR, stru