Directed Evolution to Low Nanomolar Affinity of a Tumor-Targeting Epidermal Growth Factor Receptor-Binding Affibody Molecule
Keywords: ABD, albumin binding domain (46 amino acid residues) derived from streptococcal protein G; EGFR, epidermal growth factor receptor; ECD, extracellular domain; RU, resonance units; scFv, single-chain Fv fragment; BIA, biospecific interaction analysis; CD, c