Pharmacology of smac mimetics; chemotype differentiation based on physical association with caspase regulators and cellular transport
Keywords: SM, smac mimetic; IAP, inhibitor of apoptosis protein; BIR, baculoviral IAP repeat; PCD, programmed cell death; TNF, tumor necrosis factor; TRAIL, tumor necrosis factor-related apoptosis-inducing ligand; Cyt c, cytochrome c; Smac/DIABLO, second mitochondr