Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones
Keywords: ERK5 inhibitor; Kinase selectivity; Benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-one; BMK1; big MAP kinase 1; DIEA; N,N-diisopropylethylamine; DCAMKL2; doublecortin and CaM kinase-like 2; DMA; N,N-dimethylacetamide; EGF; epidermal growth factor; ERK5; extrace