Therapeutic polo-like kinase 1 inhibition results in mitotic arrest and subsequent cell death of blasts in the bone marrow of AML patients and has similar effects in non-neoplastic cell lines
Keywords: بیوپسی مغز استخوان; PLK1; Polo-like kinase 1; AML; acute myeloid leukemia; BMB; bone marrow biopsies; AML-MRC; AML with myelodysplasia related changes; CAE; chloroacetate esterase; HPF; high power field; HSCT; hematopoietic stem cell transplantation; AML; PLK1 inhibition; BI