Mapping the binding pocket of a novel, high-affinity, slow dissociating tachykinin NK3 receptor antagonist: Biochemical and electrophysiological characterization
Keywords: RO5328673; Dual NK2/NK3 antagonist; Inositol phosphate accumulation; Firing frequency; Locomotor activity; NK3 modeling; SP; substance P; NKA; neurokinin A; NKB; neurokinin B; GPCRs; G-protein coupled receptors; IP; inositol phosphates; DA; dopamine; NA;