Compositional perspectives on human brain aging
Keywords: پیری مغزی; Base composition; Brain aging; Expression pattern; GC level; GC3
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Plasma β-amyloid peptides in canine aging and cognitive dysfunction as a model of Alzheimer's disease
Keywords: پیری مغزی; Amyloid-beta protein; Plasma; Alzheimer's disease; Animal behavior; Canine; ELISA; Neurodegeneration; Brain aging
Psychopatologia chorób układu nerwowego w wieku podeszłym
Keywords: پیری مغزی; objawy psychopatologiczne; choroby zwyrodnieniowe układu nerwowego; starzenie mózgu; otępieniepsychopathological symptoms; neurodegenerative diseases; brain aging; dementia
Effects of Cistanche deserticola on behavior and signs of cataract and retinopathy in senescence-accelerated OXYS rats
Keywords: پیری مغزی; Behavior; Brain aging; Cistanche deserticola; Senescence-accelerated OXYS rats;
Physiological and biochemical effects of 17β estradiol in aging female rat brain
Keywords: پیری مغزی; E2; 17β-estradiol; 4-HNE; 4-hydroxynonenal; AD; Alzheimer's disease; CNS; Central nervous system; GLUT4; Glucose transporter-4; HRT; Hormone replacement therapy; MDA; Malondialdehyde; MAO; Monoamine oxidase; ROS; Reactive oxygen species; Brain aging; End
Changes with aging in the dopaminergic and noradrenergic innervation of rat neocortex
Keywords: پیری مغزی; Brain aging; Monoaminergic; Cognitive impairment; Morris water maze
Imaging of a glucose analog, calcium and NADH in neurons and astrocytes: Dynamic responses to depolarization and sensitivity to pioglitazone
Keywords: پیری مغزی; Glycolysis imaging; Calcium signaling; Brain aging; Metabolic dysregulation; Thiazolidinedione
Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer's pathology and APOE genotype
Keywords: پیری مغزی; Astrocytes; Microarray analysis; Astrocyte transcriptome; Brain aging; Alzheimer's disease; APOE;
A genome-wide association study of aging
Keywords: پیری مغزی; Genome-wide association analysis; Mortality; Disease-free survival; Longevity; Aging; Brain aging;
Persistent increase of d-aspartate in d-aspartate oxidase mutant mice induces a precocious hippocampal age-dependent synaptic plasticity and spatial memory decay
Keywords: پیری مغزی; d-Aspartate; NMDA receptors; Synaptic plasticity; Reference memory; Hippocampus; Brain aging;
Increased d-aspartate brain content rescues hippocampal age-related synaptic plasticity deterioration of mice
Keywords: پیری مغزی; d-Aspartate; NMDA receptors; Synaptic plasticity; Reference memory; Hippocampus; Brain aging
Magnetic resonance imaging of cerebral involutional changes in dogs as markers of aging: An innovative tool adapted from a human visual rating scale
Keywords: پیری مغزی; Brain aging; Canine cerebral atrophy; Hippocampus; Magnetic resonance imaging; Visual rating scale
Increased intrinsic neuronal vulnerability and decreased beneficial reaction of macrophages on axonal regeneration in aged rats
Keywords: پیری مغزی; Neuronal survival and axonal regeneration; Brain aging; Neural damage; Macrophages;
Association of matrix metalloproteinases with MRI indices of brain ischemia and aging
Keywords: پیری مغزی; MMPs; Brain MRI; Framingham; Brain aging
Stress-induced senescence in human and rodent astrocytes
Keywords: پیری مغزی; Aging; Astrocyte senescence; Brain aging; Cellular senescence
Multivariable network associated with cognitive decline and dementia
Keywords: پیری مغزی; Brain aging; Dementia; Data base analysis; Connectivity map; Predictive factors
Featured ArticleOutcome over seven years of healthy adults with and without subjective cognitive impairment
Keywords: پیری مغزی; Subjective cognitive impairment; Subjective cognitive complaints; Brain aging; Cognition; Mild cognitive impairment; Outcome studies; Longitudinal studies; Dementia; Risk factors for dementia; Neuropsychological testing;
Age-associated changes in synaptic lipid raft proteins revealed by two-dimensional fluorescence difference gel electrophoresis
Keywords: پیری مغزی; 2D DIGE; Brain aging; Energy metabolism; Lipid rafts; Synaptic dysfunction
Microglia-aging: Roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging
Keywords: پیری مغزی; Autophagy; Brain aging; Lipofuscin; Lysosomal storage; Microglia aging; Mitochondrial transcription factor A; Reactive oxygen species
Activation of c-Jun-N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging
Keywords: پیری مغزی; Brain aging; Mitochondria; Pyruvate dehydrogenase; JNK; Neurodegeneration
Screening of innate immune receptors in neurodegenerative diseases: A similar pattern
Keywords: پیری مغزی; Innate immunity; Toll-like receptors; CD14; Brain aging; Neurodegenerative diseases; Alzheimer's disease; Parkinson's disease; Lewy bodies dementia; Amyotrophic lateral sclerosis
Variations in excitatory and inhibitory postsynaptic protein content in rat cerebral cortex with respect to aging and cognitive status
Keywords: پیری مغزی; brain aging; excitatory; inhibitory; postsynaptic proteins; cognitive impairmentAI, aged cognitively impaired; AU, aged cognitively unimpaired; GABAA, GABA type A; GluR2, glutamate receptor 2; HRP, horseradish peroxidase; LTD, long-term depression; LTP, l
Brain aging: The zinc connection
Keywords: پیری مغزی; Synaptic plasticity; Synaptic pathology; Brain aging; Zinc homeostasis; Mitochondrial metabolic competence; Mitochondrial dysfunction
Impairments of astrocytes are involved in the d-galactose-induced brain aging
Keywords: پیری مغزی; d-galactose; Astrocytes; Nitric oxide; Brain aging; Rats
Cognitive and functional status in the extreme longevity
Keywords: پیری مغزی; Extreme longevity; Brain aging; Cognitive decline in centenarians; Functional status of centenarians
Insights on eukaryotic translation initiation factor 5A (eIF5A) in the brain and aging
Keywords: پیری مغزی; eIF5A; eIF-5A; Dendritic translation; Varicosity; Brain aging; Long-term memory;
Mitochondrial nitric oxide synthase, mitochondrial brain dysfunction in aging, and mitochondria-targeted antioxidants
Keywords: پیری مغزی; mtNOS; NOS cellular distribution; Mitochondrial dysfunction; Brain aging; Vitamin E as antioxidant; Mitochondria-targeted antioxidants
Phosphatidylserine (PS) as a potential nutraceutical for canine brain aging: A review
Keywords: پیری مغزی; phosphatidylserine; brain aging; cognitive dysfunction; dogs; neuroprotection
The pre-mild cognitive impairment, subjective cognitive impairment stage of Alzheimer's disease
Keywords: پیری مغزی; Subjective cognitive impairment; Cognitive complaints; Brain aging; Mild cognitive impairment; Dementia; Alzheimer's disease;
Brain aging modulates the neuroprotective effects of estrogen on selective aspects of cognition in women: A critical review
Keywords: پیری مغزی; Estrogen; Cognitive functioning; Postmenopausal women; Brain aging; Progestins
Depolarization and cardiolipin depletion in aged rat brain mitochondria: Relationship with oxidative stress and electron transport chain activity
Keywords: پیری مغزی; Mitochondria; Mitochondrial membrane potential; Cardiolipin; Electron transport chain; Lipid peroxidation; Brain aging
Changes in hippocampal synapses and learning-memory abilities in age-increasing rats and effects of tetrahydroxystilbene glucoside in aged rats
Keywords: پیری مغزی; memory; synapses; synaptophysin; tetrahydroxystilbene glucoside; brain aging; Alzheimer diseaseAD, Alzheimer disease; ANOVA, analysis of variance; IOD, integrated optic density; SYP, synaptophysin; TSG, 2,3,5,4′-tetrahydroxystilbene-2-O-β-d-glucoside
Morphological substrates of cognitive decline in nonagenarians and centenarians: A new paradigm?
Keywords: پیری مغزی; Brain aging; Dementia; Lesions; Neuropathology; Oldest-old; Vascular
Domoic acid preconditioning and seizure induction in young and aged rats
Keywords: پیری مغزی; Brain aging; Domoic acid; Intrahippocampal; Seizures; Pharmacological preconditioning; Clearance
The role of insulin and neurotrophic factor signaling in brain aging and Alzheimer’s Disease
Keywords: پیری مغزی; Insulin resistance; TZDs (thiazolidinediones); Brain aging
Neuroprotective effects of estradiol in hippocampal neurons and glia of middle age mice
Keywords: پیری مغزی; Brain aging; Dentate gyrus; Neurogenesis; Estradiol; Neuroprotection; 5-bromo-2′-deoxyuridine (BrdU); Glial fibrillary acidic protein (GFAP); Hilar neurons; Lipofuscin; doublecortin; Ki67E2, 17β estradiol; BrdU, bromodeoxyuridine; DG, dentate gyrus; SGZ,
Complex mental activity and the aging brain: Molecular, cellular and cortical network mechanisms
Keywords: پیری مغزی; Brain aging; Dementia; Brain reserve; Neuroplasticity; Compensation; Mental activity
Increased levels of granular tau oligomers: An early sign of brain aging and Alzheimer's disease
Keywords: پیری مغزی; Alzheimer's disease (AD); Tau; Atomic force microscopy (AFM); Granular tau oligomer; Braak stage; Brain aging
Acupuncture regulates the aging-related changes in gene profile expression of the hippocampus in senescence-accelerated mouse (SAMP10)
Keywords: پیری مغزی; Brain aging; Acupuncture; cDNA microarray; Hippocampus; Points specificity
A neurocomputational model of stochastic resonance and aging
Keywords: پیری مغزی; Stochastic resonance; Neuromodulation; Brain aging; Neural network; Sensory detection
Cognitive impact of neuronal pathology in the entorhinal cortex and CA1 field in Alzheimer's disease
Keywords: پیری مغزی; Brain aging; Hippocampus; Neurodegeneration; Neuronal loss; Stereology
Immunization with fibrillar Aβ1–42 in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Aβ
Keywords: پیری مغزی; Alzheimer's disease; Alum; Beta-amyloid; Brain aging; Dog
Proteomics analysis provides insight into caloric restriction mediated oxidation and expression of brain proteins associated with age-related impaired cellular processes: Mitochondrial dysfunction, glutamate dysregulation and impaired protein synthesis
Keywords: پیری مغزی; Proteomics; Brain aging; Oxidative stress; Caloric restriction; Cellular dysfunction
Therapeutic agents for the treatment of cognitive dysfunction syndrome in senior dogs
Keywords: پیری مغزی; CDS; Cognitive dysfunction syndrome; DISHA; acronym for Disorientation, altered Interactions with people and other pets, Sleep-wake cycle alterations, Housesoiling and altered Activity Level; TGTA; Toronto General Test Apparatus; DHA; docosahexaenoic ac
Stereologic analysis of hippocampal Alzheimer's disease pathology in the oldest-old: Evidence for sparing of the entorhinal cortex and CA1 field
Keywords: پیری مغزی; Brain aging; Centenarians; Neuronal loss;
Humoral immunity in brain aging and Alzheimer's disease
Keywords: پیری مغزی; Disorders of the nervous system; Alzheimer's-miscellaneous; Brain aging; Cytoskeleton; Immunoglobulins; Microtubules; Neurodegeneration; Tau;