Structural Basis of C-terminal β-Amyloid Peptide Binding by the Antibody Ponezumab for the Treatment of Alzheimer's Disease
Keywords: AD, Alzheimer's disease; Aβ, β-amyloid; APP, amyloid precursor protein; CNS, central nervous system; hAPP, human APP; CSF, cerebrospinal fluid; PDB, Protein Data Bank; CDR, complementarity-determining region; PBS, phosphate-buffered saline; BSA, bovine se