
Long-term toxicity studies in dogs support the safety of the special extract ERr 731 from the roots of Rheum rhaponticum
Keywords: bw، وزن بدن; ANOVA, analysis of variance; bw, body weight; DES, diethylstilbestrol; DOR, desoxyrhapontigenin; E2, 17β-estradiol; ERr, extract Rheum rhaponticum; ER, estrogen receptor; GLP, Good Laboratory Practice; NOAEL, no-observed-adverse-effect-level; PIC, piceata