
Ethyl pyruvate-mediated Nrf2 activation and hemeoxygenase 1 induction in astrocytes confer protective effects via autocrine and paracrine mechanisms
Keywords: EP, ethyl pyruvate; Nrf2, nuclear factor E2-related factor 2; HO-1, hemeoxygenase 1; ARE, antioxidant response element; ZnPP, zinc protoporphyrin; GDNF, glial cell line-derived neurotrophic factor; GSH, glutathione; bZIP, basic-region leucine zipper; NQO1