دانلود مقالات ISI درباره Ca-4, Combretastatin A-4 + ترجمه فارسی

A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells

Keywords: Combretastatin A-4 (PubChem CID:5351344); Colchicine (PubChem CID: 6167); Cisplatinum (PubChem CID: 441203); Taxol (PubChem CID: 36314); Vincristine (PubChem CID: 5978)BSA, bovine serum albumin; CDDP, cisplatinum; CA-4, combretastatin A-4; DCFH-DA, 2′,7′-

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The design and discovery of water soluble 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multitargeted receptor tyrosine kinase inhibitors and microtubule targeting antitumor agents

Keywords: CA-4, combretastatin A-4; VEGFR-2, vascular endothelial growth factor receptor-2; RTKs, receptor tyrosine kinases; 2ME2, 2-methoxyestradiol; PDGFR-β, platelet-derived growth factor receptor β; CAM, chorioallantoic membraneTyrosine kinase inhibitors; Singl

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

(4-Methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone inhibits tubulin polymerization, induces G2/M arrest, and triggers apoptosis in human leukemia HL-60 cells

Keywords: BrdU, 5-bromo-20-deoxyuridine; CA-4, combretastatin A-4; CA-4P, combretastatin-A4-phosphate; DI, damage index; MTT, 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide; PHT, (4-methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone; TNF-α, tumor nec

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis of N4-(substituted phenyl)-N4-alkyl/desalkyl-9H-pyrimido[4,5-b]indole-2,4-diamines and identification of new microtubule disrupting compounds that are effective against multidrug resistant cells

Keywords: CA-4, combretastatin A-4; MDR, multidrug resistance; Pgp, P-glycoprotein’; Rr, relative resistance; DAMA colchicine, N-deacetyl-N-(2-mercaptoacetyl)colchicinePyrimido[4,5-b]indole-2,4-diamines; Microtubules; Multidrug resistance

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis and biochemical activities of antiproliferative amino acid and phosphate derivatives of microtubule-disrupting β-lactam combretastatins

Keywords: Antiproliferative; Beta-lactam; Combretastatin A-4; Prodrug; Solubility; TubulinCA-1, combretastatin A-1; CA-4, combretastatin A-4; DIPEA, diisopropylethylamine; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NAC, N-acetylcolchicine; P

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Imidazolone–amide bridges and their effects on tubulin polymerization in cis-locked vinylogous combretastatin-A4 analogues: Synthesis and biological evaluation

Keywords: CSI, colchicine site inhibitor; CA-4, combretastatin A-4; CA-4P, CA-4 phosphate disodium; TMP, trimethoxyphenylImidazolone–amide; Tubulin polymerization inhibitor; Antitumor agent

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Enhanced anti-tumor activity by the combination of TRAIL/Apo-2L and combretastatin A-4 against human colon cancer cells via induction of apoptosis in vitro and in vivo

Keywords: TRAIL/Apo-2L, the tumor necrosis factor (TNF) α-related apoptosis-inducing ligand; CA-4, combretastatin A-4; PI, propidium iodide; PBS, phosphate buffer saline; CI, combination index; FLIP, FLICE-inhibitory protein; CA-4P, combretastatin A-4 phosphate; NF

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones

Keywords: CA-4, combretastatin A-4; CA-4P, combretastatin A-4 phosphate; DAMA-colchicine, N-deacetyl-N-(2-mercaptoacetyl)-colchicine; DCM, dichloromethane; GTP, guanidine triphosphate; HRMS, high resolution molecular ion determination; IR, infra red; LDA, lithium d

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2011 سفارش ترجمه

Chamaecypanone C, a novel skeleton microtubule inhibitor, with anticancer activity by trigger caspase 8-Fas/FasL dependent apoptotic pathway in human cancer cells

Keywords: CA-4, combretastatin A-4; CCD, charge-coupled device; DIC, differential interference contrast; DMSO, dimethyl sulfoxide; FITC, fluorescent isothiocyanate; GFP, green fluorescent protein; HRP, horseradish peroxidase; MAP, Microtubule-associated protein; MD

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه