Keywords: CPT-11; irinotecan, 7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin; SN-38; irinotecan metabolite, ethyl-10-hydroxy-camptothecin; DSC; Differential Scanning Calorimetry; P; partition coefficient; DSPC; l-α-Distearoyl-phospathidylcholin
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Mitochondria response to camptothecin and hydroxycamptothecine-induced apoptosis in Spodoptera exigua cells
Keywords: Mitochondrion; Camptothecins; Mitochondrial membrane potential; Ca2Â +; Â Spodoptera exigua;
Germ cell mutagenicity of topoisomerase I inhibitor topotecan detected in the male mouse-dominant lethal study
Keywords: Dominant lethality; Camptothecins; Topoisomerase I; DNA oxidative stress; N-acetylcysteine; Genomic alterations;
Experimental and theoretical spectroscopic and structural study of A-ring substituted camptothecins
Keywords: Camptothecins; Optical spectroscopy; Mass spectrometry; Quantum chemistry
Enhanced active liposomal loading of a poorly soluble ionizable drug using supersaturated drug solutions
Keywords: Liposome; Nanotechnology; Cyclodextrins; Supersaturation; Camptothecins; AR-67;
Mécanismes moléculaires et déterminants de la réponse aux inhibiteurs de topo-isomérases I
Keywords: ADN topo-isomérase I; inhibiteurs de topo-isomérases; camptothécines; lésions de l'ADN; apoptose; résistance; pharmacologie; agents anticancéreux; DNA topoisomerase I; topoisomerase inhibitors; camptothecins; DNA damage; apoptosis; resistance; pha
Clinical pharmacokinetics of the new oral camptothecin gimatecan: The inter-patient variability is related to α1-acid glycoprotein plasma levels
Keywords: Camptothecins; Pharmacokinetics; Inter-patient variability; α1-Acid glycoprotein; Statistical analysis;
Determination of intraliposomal pH and its effect on membrane partitioning and passive loading of a hydrophobic camptothecin, DB-67
Keywords: Liposomes; Nanoparticles; Intraliposomal pH; Membrane binding; Lipid bilayers; Camptothecins; Tumor drug delivery; Fluorescence; Drug encapsulation
Exploitation of drug-induced Bcl-2 overexpression for restoring normal apoptosis function: A promising new approach to the treatment of multidrug resistant cancer
Keywords: Multidrug resistance; Camptothecins; Acute lymphoblastic leukemia; Bcl-2; Bcl-2 inhibitor
Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series
Keywords: Camptothecins; DNA topoisomerase I; Antitumor activity; Cyotoxicity; BCRP; DNA cleavage
Sensitization to gimatecan-induced apoptosis by tumor necrosis factor-related apoptosis inducing ligand in prostate carcinoma cells
Keywords: TRAIL, TNF-related apoptosis inducing ligand; TPT, topotecan; ST1481 (gimatecan), 7-butoxyiminomethylcamptothecin; siRNA, small interfering RNAGimatecan; TRAIL; Prostate carcinoma; Apoptosis; Cell sensitivity; Camptothecins
Evaluation of the toxic potentials of a new camptothecin anticancer agent CKD-602 on fertility and early embryonic development in rats
Keywords: Camptothecins; CKD-602; Fertility and early embryonic development study; Rats
Inhibition of efflux transporter ABCG2/BCRP does not restore mitoxantrone sensitivity in irinotecan-selected human leukemia CPT-K5 cells: Evidence for multifactorial multidrug resistance
Keywords: Camptothecins; CPT-K5; Resistant ratio; BCRP; TransporterBCRP, breast cancer resistant protein (ABCG2); MX, mitoxantrone; NOV, novobiocin; MDR, multidrug resistance; Top2, topoisomerase II; CPTs, camptothecins; TPT, topotecan; CPT-11, irinotecan; AML, acu
Towards new camptothecins. Part 3: Synthesis of 5-methoxycarbonyl camptothecin
Keywords: Camptothecins; Mannich reaction; Bredereck's reagent;
Synergistic effects of protein tyrosine kinase inhibitor genistein with camptothecins against three cell lines in vitro
Keywords: Genistein; Camptothecins; Cell line; Synergism; Apoptosis; Cell cycle
Plants as a source of anti-cancer agents
Keywords: Camptothecins; Combretastatins; Flavopiridol; Podophyllotoxins; Taxanes; Vinca alkaloids; Cell cycle target inhibitors;
4-Week repeated intravenous dose toxicity study of a new camptothecin anticancer agent CKD-602 in dogs
Keywords: Camptothecins; Repeated intravenous dose; Subacute toxicity; Target organ, NOAEL; Dogs;
Cellular Basis of Antiproliferative and Antitumor Activity of the Novel Camptothecin Derivative, Gimatecan, in Bladder Carcinoma Models
Keywords: Bladder carcinoma; DNA topoisomerase I; gimatecan; camptothecins; antitumor activity;
The novel lipophilic camptothecin analogue gimatecan is very active in vitro in human neuroblastoma: A comparative study with SN38 and topotecan
Keywords: Gimatecan; Camptothecins; Topoisomerase I inhibitors; Neuroblastoma; Alkaline comet assay; DNA strand breaks;