G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 status
Keywords: اپی ژنتیک سرطان; Cancer epigenetics; Chemical probes; UNC0638; Chemotherapeutics; Non-homologous end joining; DSB; double strand break; NHEJ; non-homologous end joining; SGC; Structural Genomics Consortium; DDR; DNA damage response; IC50; inhibitory concentration 50%; WT;