Ceramide signaling targets the PP2A-like protein phosphatase Sit4p to impair vacuolar function, vesicular trafficking and autophagy in Isc1p deficient cells
Keywords: CAPP, Ceramide-activated Protein Phosphatase; CLS, chronological lifespan; CPY, carboxypeptidase Y; Cvt, cytoplasm-to-vacuole targeting; DMSO, dimethyl sulfoxide; DTT, dithiothreitol; EDTA, ethylenediamine tetraacetic acid; ER, endoplasmic reticulum; FACS