Keywords: ایمنی قلب; iPSC-CM cardiomyocytes; Cardiac safety; Safety pharmacology; SPS; Education; Strategy; Health authorities; FDA; Non-clinical models; In silico; In vitro; In vivo;
مقالات ISI ایمنی قلب (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: ایمنی قلب; High-throughput; Compound screening; Cardiac safety; Open source; Action potential; Mathematical model;
Keywords: ایمنی قلب; AV; atrioventricular; AVB; atrioventricular block; ECG; electrocardiogram; FDA; US Food and Drug Administration; FDO; first-dose observation; FREEDOMS; FTY720 Research Evaluating Effects of Daily Oral Therapy in Multiple Sclerosis; GIRK; G-protein-gated i
Comparison of one- and three-lead ECG to measure cardiac intervals and differentiate drug-induced multi-channel block
Keywords: ایمنی قلب; Automated ECG analysis; Cardiac safety; CiPA; Electrocardiogram; HESI; Methods; Multichannel block; QT interval; QT subintervals; Spatial magnitude lead;
Assessment of extracellular field potential and Ca2 + transient signals for early QT/pro-arrhythmia detection using human induced pluripotent stem cell-derived cardiomyocytes
Keywords: ایمنی قلب; Human stem cell-derived cardiomyocytes; Extracellular field potential; Ca2Â + transient; QT prolongation; Pro-arrhythmia; Cardiac safety; Drug discovery and development;
An evaluation of multiple algorithms for the measurement of the heart rate corrected JTpeak interval
Keywords: ایمنی قلب; Electrocardiogram; Cardiac safety; QT; Long QT syndrome; CiPA; Torsade de pointes;
Evaluation of cardiac function in unrestrained dogs and monkeys using left ventricular dP/dt
Keywords: ایمنی قلب; Cardiac safety; Inotropy; Left ventricular dP/dt; Lusitropy; Nonclinical; Telemetry methods;
PKPD modelling of PR and QRS intervals in conscious dogs using standard safety pharmacology data
Keywords: ایمنی قلب; AIC; Akaike information criterion; BSV; between subject variability; BLQ; below the limit of quantification; CV; cardiovascular; ECG; electrocardiogram; hERG; human ether-a-go-go-related gene channel; hCav1.2; human cardiac calcium channel; hNav1.5; human
Elacytarabine in relapsed/refractory acute myeloid leukaemia: An evaluation of clinical efficacy, pharmacokinetics, cardiac safety and effects on lipid profile
Keywords: ایمنی قلب; Elacytarabine; AML; Cardiac safety; ECG; QT; Cholesterol; Lipoprotein
Nuestra experiencia con fingolimod
Keywords: ایمنی قلب; Bradicardia; Esclerosis múltiple remitente recurrente; Fingolimod; Seguridad cardiológica; Bradycardia; Relapsing Remitting Multiple Sclerosis; Fingolimod; Cardiac safety;
Prediction of Thorough QT study results using action potential simulations based on ion channel screens
Keywords: ایمنی قلب; AP(D); action potential (duration); AZ; AstraZeneca; B&Q2; IonWorks Barracuda and second Quattro screening dataset; GLP; good laboratory practice; GSK; GlaxoSmithKline; IC50; concentration for 50% inhibition; ICaL; long-lasting-type calcium current; IKr;
A public-private consortium advances cardiac safety evaluation: Achievements of the HESI Cardiac Safety Technical Committee
Keywords: ایمنی قلب; ADRs; adverse drug reactions; CDER; Center for Drug Evaluation and Research; cTn; cardiac troponin; CV; cardiovascular; EMA; European Medicines Agency; EWG; Expert Working Group; ECG; electrocardiogram; HESI; Health and Environmental Sciences Institute; h
Evaluation of an in silico cardiac safety assay: Using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge
Keywords: ایمنی قلب; AP (D); Action Potential (Duration); ECG; electrocardiogram; ECVAM; European Centre for the Validation of Alternative Methods; FLIPR; FLuorescence Imaging Plate Reader; GSK; GlaxoSmithKline; hERG; human-Ether-a-go-go Related Gene; IC50; Concentration for
Quickly finding a needle in a haystack: A new automated cardiac arrhythmia detection software for preclinical studies
Keywords: ایمنی قلب; ECG, electrocardiograms; LVP, left ventricular pressure; AV-block II, type 2 atrio-ventricular blocksAutomated analysis; Arrhythmia; Cardiac safety; ECG; Methods; Software
The Telemetric and Holter ECG Warehouse (THEW): The first three years of development and research
Keywords: ایمنی قلب; Database; ECG/EKG; Electrocardiogram; Cardiac safety; QT; Long QT syndrome; Acute myocardial infarction; Coronary syndrome; Acute myocardial infarction; Thorough QT studies; Healthy normal; Torsades de pointes; Clinical trials
A unique digital electrocardiographic repository for the development of quantitative electrocardiography and cardiac safety: the Telemetric and Holter ECG Warehouse (THEW)
Keywords: ایمنی قلب; Database; ECG; Electrocardiogram; Cardiac safety; QT; Long QT syndrome; Acute myocardial infarction; Coronary syndrome; Acute myocardial infarction; Thorough QT studies; Healthy normal; Torsades de pointes
Cardiac safety of formoterol 12 μg twice daily in patients with chronic obstructive pulmonary disease
Keywords: ایمنی قلب; COPD; Formoterol; Cardiac safety
Understanding proarrhythmic potential in therapeutic drug development: alternate strategies for measuring and tracking repolarization
Keywords: ایمنی قلب; Repolarization; Cardiac safety; RMS ECG;
Docetaxel and trastuzumab in the adjuvant setting: Translating SABCS into clinical practice
Keywords: ایمنی قلب; Docetaxel; Trastuzumab; Disease-free survival; Cardiac safety;
ILSI-HESI cardiovascular safety subcommittee initiative: Evaluation of three non-clinical models of QT prolongation
Keywords: ایمنی قلب; APD; Arrhythmia; Cardiac repolarization; Cardiac safety; Cardiovascular dog; HERG; Preclinical; Purkinje fiber; QT; Risk assessment; Sudden death; Torsades
Estimation of potency of HERG channel blockers: Impact of voltage protocol and temperature
Keywords: ایمنی قلب; HERG; Patch clamp; HEK293 cell line; Cardiac safety; Methods; HERG channel blockers; Potency estimation;
A Randomized Trial Comparing the Cardiac Rhythm Safety of Moxifloxacin vs Levofloxacin in Elderly Patients Hospitalized With Community-Acquired Pneumonia
Keywords: ایمنی قلب; ambulatory ECG monitoring; cardiac repolarization; cardiac safety; community-acquired pneumonia; elderly; levofloxacin; moxifloxacin; QTc intervalATS = American Thoracic Society; CAP = community-acquired pneumonia; CI = confidence interval; H-12 = 12-lead
Automated electrophysiology in the preclinical evaluation of drugs for potential QT prolongation
Keywords: ایمنی قلب; Cardiac safety; CHO cells; hERG; Methods; PatchXpress 7000A; QT prolongation;